Results 21 to 30 of about 202,310 (299)

The Ubiquitination Machinery of the Ubiquitin System [PDF]

The Arabidopsis Book, 2014
The protein ubiquitin is a covalent modifier of proteins, including itself. The ubiquitin system encompasses the enzymes required for catalysing attachment of ubiquitin to substrates as well as proteins that bind to ubiquitinated proteins leading them to their final fate.
openaire   +4 more sources

Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity [PDF]

, 2011
Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation.
West, A., Ma, M.K-W., Adam G West, Heath, C., Carol Heath, Adam G. West, Meiji Kit-Wan Ma, Hair, A., Alan Hair   +8 more
core   +2 more sources

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells [PDF]

, 2011
Translesion DNA synthesis (TLS) is a DNA damage tolerance mechanism in which specialized low-fidelity DNA polymerases bypass replication-blocking lesions, and it is usually associated with mutagenesis.
Geacintov, Nicholas E., Tateishi, Satoshi, D'Andrea Alan, Jungmin Kim, Reißner Thomas, Goren, Zohar, Peter H L Krijger, Zvi Livneh, Hendel Ayal, Langerak, Petra, Alan D'Andrea, Kyungjae Myung, Petra Langerak, Nicholas E. Geacintov, Zohar Goren, Satoshi Tateishi, Myung Kyungjae, Goren Zohar, Kim, Jungmin, Jacobs, Heinz, Reißner, Thomas, Nicholas E Geacintov, Jacobs Heinz, Hendel, Ayal, Lee Kyoo-young, Livneh Zvi, Kyoo-young Lee, Diamant, Noam, Geacintov Nicholas E., Krijger, Peter H. L., Peter H. L. Krijger, Noam Diamant, Kim Jungmin, Carell Thomas, Heinz Jacobs, Carell, Thomas, D'Andrea, Alan, Ayal Hendel, Thomas Reissner, Tateishi Satoshi, Myung, Kyungjae, D'Andrea, Alan, Krijger Peter H. L., Lee, Kyoo-young, Thomas Carell, Diamant Noam, Livneh, Zvi, Langerak Petra   +47 more
core   +2 more sources

Global Screening of LUBAC and OTULIN Interacting Proteins by Human Proteome Microarray

Frontiers in Cell and Developmental Biology, 2021
Linear ubiquitination is a reversible posttranslational modification, which plays key roles in multiple biological processes. Linear ubiquitin chain assembly complex (LUBAC) catalyzes linear ubiquitination, while the deubiquitinase OTULIN (OTU ...
Lijie Zhou, Lijie Zhou, Yingwei Ge, Yesheng Fu, Bo Wu, Yong Zhang, Lei Li, Chun-Ping Cui, Siying Wang, Lingqiang Zhang   +9 more
doaj   +1 more source

In the family with ubiquitin [PDF]

The EMBO Reports, 2011
The Cold Spring Harbor meeting on 'The Ubiquitin Family', held in May 2011, brought together scientists from a wide range of fields under the umbrella of ubiquitin and ubiquitin-like protein structure, function and regulation.
Alexandru, Gabriela, Pariente, Nonia, Xirodimas, Dimitris   +2 more
openaire   +4 more sources

Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer

Cells, 2019
Histone ubiquitination is a critical epigenetic mechanism regulating DNA-driven processes such as gene transcription and DNA damage repair. Importantly, the cellular machinery regulating histone ubiquitination is frequently altered in cancers.
Lucile M-P Jeusset, Kirk J McManus
doaj   +1 more source

Quantitative Ubiquitylomic Analysis of the Dynamic Changes and Extensive Modulation of Ubiquitylation in Papaya During the Fruit Ripening Process

Frontiers in Plant Science, 2022
Lysine ubiquitination is a highly conserved post-translational modification with diverse biological functions. However, there is little available information on lysine ubiquitination of non-histone proteins in papaya (Carica papaya L.).
Yuxing Mo, Bian Jiang, Jingxin Huo, Jiayi Lu, Xiaoyue Zeng, Yan Zhou, Tao Zhang, Min Yang, Yuerong Wei, Kaidong Liu   +9 more
doaj   +1 more source

Generation and physiological roles of linear ubiquitin chains [PDF]

, 2012
Ubiquitination now ranks with phosphorylation as one of the best-studied post-translational modifications of proteins with broad regulatory roles across all of biology.
Iwai Kazuhiro, Walczak, H, Walczak, Henning, Kazuhiro Iwai, Walczak Henning, Đikić, Ivan, Ivan Dikic, Iwai, Kazuhiro, Iwai, K, Dikic, I, Dikic Ivan, Henning Walczak   +11 more
core   +1 more source

On the possibility that bond strain is the mechanism of RING E3 activation in the E2-catalyzed ubiquitination reaction [PDF]

, 2022
Ubiquitination is a type of post translational modification wherein the small protein ubiquitin (Ub) is covalently bound to a lysine on a target protein.
Isaiah, Sumner, Jay-Anne K., Johnson
core   +2 more sources

Regulation and effects of IRF-1 and p53 ubiquitination [PDF]

, 2013
Protein ubiquitination is a key regulator of both protein stability and activity, and is involved in the regulation of a vast variety of cellular pathways.
Landré, Vivien
core   +3 more sources