Results 141 to 150 of about 23,719 (175)

Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability. [PDF]

open access: yesNat Commun
Dürauer S   +18 more
europepmc   +1 more source

Integrative Omics Reveals Glutamine Catabolism-Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading. [PDF]

open access: yesAdv Sci (Weinh)
Ding Y   +14 more
europepmc   +1 more source

Boosting CAR T-cell efficacy by blocking proteasomal degradation of membrane antigens.

open access: yesBlood
Rieger L   +32 more
europepmc   +1 more source

Chemical chromatin ubiquitylation

Current Opinion in Chemical Biology, 2018
Histone modifications dynamically regulate chromatin structure and function, thereby mediating many processes that require access to DNA. Chemical protein synthesis has emerged as a powerful approach for generating homogeneously modified histone analogues in workable amounts for subsequent incorporation into nucleosome arrays for biochemical ...
Muhammad, Jbara   +3 more
openaire   +2 more sources

IAPs, RINGs and ubiquitylation

Nature Reviews Molecular Cell Biology, 2005
The inhibitor of apoptosis (IAP) proteins all contain one or more baculoviral IAP repeat motifs, through which they interact with various other proteins. Many IAPs also have another zinc-binding motif, the RING domain, which can recruit E2 ubiquitin-conjugating enzymes and catalyse the transfer of ubiquitin onto target proteins.
Vaux, David L., Silke, John.
openaire   +2 more sources

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