Degradation factor 1, Def1, regulates mRNA translation and decay through Ccr4-Not-dependent ubiquitylation of the ribosome. [PDF]
Akinniyi OT +4 more
europepmc +1 more source
K63-linked ubiquitylation of RMI1 by RNF8 is essential to its recruitment to stalled forks. [PDF]
Arun R +4 more
europepmc +1 more source
K63-linked ubiquitylation of S2P-RNAPII regulates transcription in a DNAPK inter-dependent manner in response to double-strand breaks. [PDF]
Pantazi V +11 more
europepmc +1 more source
The ubiquitin ligase CBL and Fas-associated factor 2 cooperate to regulate the innate immune response to M. tuberculosis. [PDF]
Truong T +6 more
europepmc +1 more source
Oxidative stress causes a reversible decrease of deubiquitylases activity in old vertebrate brains. [PDF]
Sahu AK +12 more
europepmc +1 more source
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity
Stability of proteins is largely controlled by post-translational covalent modifications. Among those, ubiquitylation plays a central role as it marks the proteins for proteasome-dependent degradation.
Bottrill, A +5 more
core
Proteasome dysfunction underlies HERC2-linked neurodevelopmental disorder with Angelman-like clinical features. [PDF]
Sala-Gaston J +13 more
europepmc +1 more source
Hierarchical mechanisms control the clearance of DNA lesion-stalled RNA polymerase II. [PDF]
van der Meer PJ +5 more
europepmc +1 more source
Proteasomal control of transcription factors: mechanisms, regulation and dysregulation. [PDF]
Larsen FB +4 more
europepmc +1 more source
A GA-independent, membrane-associated pathway regulates DELLA degradation during carbon/nitrogen stress. [PDF]
Chia JC.
europepmc +1 more source

