Results 151 to 160 of about 28,143 (190)

Design principles of a membrane-spanning ubiquitin ligase. [PDF]

Mol Cell
Williams C, Nocka LM, Hedger G, Parashara P, Pardon E, Latorraca NR, Pusapati GV, Sarkar P, Lartey D, Gao L, Milenkovic L, Chalk R, Steyaert J, Marqusee S, Carrique L, Bazan JF, Rouse SL, Kong JH, Siebold C, Rohatgi R.   +19 more
europepmc   +1 more source

The <i>Shigella flexneri</i> effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation. [PDF]

Elife
Saavedra-Sanchez L, Dickinson MS, Apte SS, Zhang Y, De Jong M, Skavicus S, Heaton NS, Alto NM, Coers J.   +8 more
europepmc   +1 more source

Poly-ubiquitylated transmembrane proteins outcompete other cargo for limited space inside clathrin-coated vesicles. [PDF]

Cell Rep
Liu HY, Sarkar S, Yuan F, Ashby G, Hayden CC, Huibregtse JM, Stachowiak JC.   +6 more
europepmc   +1 more source

FBXO11 suppression rewires an NPM1-centered interactome influencing the progression of myelodysplastic syndrome. [PDF]

J Clin Invest
Niederkorn M, Bezavada L, Cotton A, Palmer LE, Konada L, Hall T, Pagala VR, Zhai J, Yuan ZF, Fu Y, Steele JA, Narina S, Schild A, Wu C, Aminov S, Schieber M, McGovern E, Taylor AB, Gurbuxani S, Xu P, Ji P, Janke LJ, High AA, Kang G, Pruett-Miller SM, Weiss M, Verma A, Rampal RK, Crispino JD.   +28 more
europepmc   +1 more source

E2 variants for probing E3 ubiquitin ligase activities. [PDF]

Proc Natl Acad Sci U S A
Du J, Andree GA, Horn-Ghetko D, Stier L, Singh J, Kostrhon S, Kiss L, Mann M, Sidhu SS, Schulman BA.   +9 more
europepmc   +1 more source

FBXW7 Targets the SPT6-ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4-Nitroquinoline N-Oxide. [PDF]

MedComm (2020)
Zhang J, Yin L, You X, Xiong X, Sun Y.
europepmc   +1 more source

Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity. [PDF]

EMBO J
Arroyo-Gomez J, Murray MJ, Guérillon C, Wang J, Isaakova E, Reverón-Gómez N, Koutrouli M, Suryo Rahmanto A, Mitrofanov K, Ingham A, Schovsbo S, Weischenfeldt K, Coscia F, Typas D, Völker-Albert M, Solis V, Jensen LJ, Groth A, Mund A, Beli P, Shearer RF, Mailand N.   +21 more
europepmc   +1 more source

UBQLN2 is necessary for UBE3A-mediated proteasomal degradation of the domesticated retroelement PEG10. [PDF]

J Cell Sci
Roberts JE, Huynh PT, Carale LO, Whiteley AM.   +3 more
europepmc   +1 more source

Molecular mechanisms of CYP-13 function in C. elegans: insights into conserved P450 pathways. [PDF]

Arch Toxicol
Lim SYM.
europepmc   +1 more source

Oncogenic SOX9-TRAIP signaling drives gastric cancer progression by mediating the degradation of the CPEB3-mTORC1 tumor suppressor axis. [PDF]

World J Surg Oncol
Zhou Y, Zhu J, Ouyang C, Liu W, Huang L, Zou L, Liu B, Lu Z.   +7 more
europepmc   +1 more source