Results 121 to 130 of about 42,693 (202)

The whole-genome map of Astragalus mongholicus provides ideas for the synthesis of glutathione and flavonoid

open access: yesBMC Genomics
Background The legume Astragalus mongholicus (A. mongholicus) has a wide variety of medicinal properties. Based on the genome of A. mongholicus, this study intended to investigate the phylogenetic position of A.
Miaozhuo Yao   +5 more
doaj   +1 more source

TcdB glucosyltransferase mutants cause epithelial cell death.

open access: yes, 2012
A, TcdB and TcdB glucosyltransferase domain mutants (100 nM) were tested for their capacity to glucosylate purified Rac1 (2 uM) in the presence of 20 mM UDP-[14C]-glucose over the course of 1 h.
Jeffrey L. Franklin (114941)   +6 more
core   +1 more source

UDP-glucosyltransferase UGT84B1 regulates the levels of indole-3-acetic acid and phenylacetic acid in Arabidopsis. [PDF]

open access: yesBiochem Biophys Res Commun, 2020
Aoi Y   +9 more
europepmc   +1 more source

Omadacycline Pharmacokinetics: Characteristics, Contributing Factors, and Clinical Significance

open access: yesDrugs in R&D
Omadacycline is a novel tetracycline with a wide range of antibacterial activity. A comprehensive understanding of the factors influencing its metabolic processes is essential to optimize its therapeutic benefits and minimize any potential negative ...
Huan Sun   +5 more
doaj   +1 more source

Haplotype-resolved genome reveals haplotypic variation and the biosynthesis of medicinal ingredients in Areca catechu L.

open access: yesMolecular Horticulture
Areca catechu, as a traditional Chinese medicine, contains a high concentration of therapeutic compounds. However, the biosynthesis of these compounds is largely unexplored. We present a haplotype-resolved genome assembly and annotation for A.
Chao Wang   +13 more
doaj   +1 more source

Metabolism of conjugated sterols in eggplant. Part 1. UDP-glucose : sterol glucosyltransferase [PDF]

open access: yes, 2008
A membrane-bound UDP-glucose : sterol glucosyltransferase from Solanum melongena (eggplant) leaves was partially purified and its specificity as well as molecular and kinetic properties were defined. Among a wide spectrum of 3-OH steroids (i.e.
Zimowski, Jan, Potocka, Anna
core  

MOLECULAR CLONING AND CHARACTERIZATION OF STEVIA REBAUDIANA UDP-GLUCOSYLTRANSFERASE

open access: yes, 2003
本文对一种新的甜菊糖基转移酶进行了基因克隆和功能分析。获得的基因cDNA全长1419bp,编码473个氨基酸,蛋白质分子量约53.2K Da。与常见的糖基转移酶基因比较,相似性达44%以上,且具有糖基转移酶的保守序列。体外异源表达获得的融合蛋白,具有在花青素类和甜菊醇等糖基受体上转糖基的酶活性。在对一系列不同底物的酶活性进行比较后,推测这种糖基转移酶在体内参与了甜菊糖苷的合成。结果表明,具有广泛的底物活性的类黄酮类糖基转移酶,在甜菊体内不仅对类黄酮转糖基,而且在生成水溶性甜菊糖苷的过程中也扮演重要的角色。
陈睦传, 陈亮, 马凌波, 张大兵
core  

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