Results 51 to 60 of about 35,038 (214)

Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum

Frontiers in Plant Science, 2021
Fenugreek (Trigonella foenum-graecum), a pharmacologically important herb, is widely known for its antidiabetic, hypolipidemic, and anticancer effects. The medicinal properties of this herb are accredited to the presence of bioactive steroidal saponins ...
Jianghong Gao, Yehan Xu, Congkun Hua, Changfu Li, Yansheng Zhang   +4 more
doaj   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Histidine 352 (His352) and tryptophan 355 (Trp355) are essential for flax UGT74S1 glucosylation activity toward secoisolariciresinol.

PLoS ONE, 2015
Flax secoisolariciresinol diglucoside (SDG) lignan is a natural phytoestrogen for which a positive role in metabolic diseases is emerging. Until recently however, much less was known about SDG and its monoglucoside (SMG) biosynthesis.
Kaushik Ghose, Jason McCallum, Marva Sweeney-Nixon, Bourlaye Fofana   +3 more
doaj   +1 more source

Apple scar skin viroid causes dapple and scar skin apple diseases by disrupting phenylpropanoid‐mediated metabolic pathways

New Plant Protection, EarlyView.
Dapple apple and scar skin apple diseases are closely associated with suppression of anthocyanin biosynthesis and enhancement of suberin biosynthesis. Apple scar skin viroid (ASSVd) infection represses anthocyanin biosynthesis in apple callus. Abstract Apple scar skin viroid (ASSVd) causes dapple and scar skin apple diseases, posing serious threats to ...
Lingzhu He, Huiyuan Xu, Tao Zhou, Naoi Takashi, Sano Teruo, Guojun Hu, Jipeng Xie, Xiuling Yang, Shifang Li, Zhixiang Zhang   +9 more
wiley   +1 more source

Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei [PDF]

, 2014
Trypanosoma brucei expresses a diverse repertoire of N-glycans, ranging from oligomannose and paucimannose structures to exceptionally large complex N-glycans.
Damerow, Manuela, Ferguson, Michael A. J.; id_orcid, Güther, M. Lucia S., Wu, Di, Mehlert, Angela, Rodrigues, Joao A.   +5 more
core   +1 more source

Exploring regulatory network of icariin synthesis in Herba Epimedii through integrated omics analysis

Frontiers in Plant Science
Herba Epimedii’s leaves are highly valued in traditional Chinese medicine for their substantial concentration of flavonoids, which play a crucial role in manifesting the plant’s therapeutic properties.
Xuedong Zhu, Shiqi Wen, Shiqi Wen, Hameed Gul, Pan Xu, Yang Yang, Yang Yang, Ximei Liao, Ximei Liao, Yunling Ye, Yunling Ye, Zijian Xu, Zijian Xu, Xiaofang Zhang, Lin Wu, Lin Wu, Lin Wu   +16 more
doaj   +1 more source

Exploring the significance of glycosylation in prostate cancer subtyping through single-cell analysis [PDF]

Journal of Men's Health
Prostate cancer impacts millions of men worldwide and causes significant disease burden. Glycosylation is the post-translational modification offering novel therapeutics for prostate cancer.
Shijun Tong, Wenhui Zhu, Jing Zhai, Guanxiong Ding   +3 more
doaj   +1 more source

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls

, 2007
Arabidopsis cell walls contain large amounts of pectins and hemicelluloses, which are predominantly synthesized via the common precursor UDP-glucuronic acid.
Tenhaken, Raimund, Klinghammer, Michaela
core   +1 more source

Safety of the proposed amendment of the specifications for steviol glycosides (E 960) as a food additive: Rebaudioside M produced via enzyme‐catalysed bioconversion of purified stevia leaf extract

EFSA Journal, 2019
The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of the proposed amendment of the specifications for steviol glycosides (E 960) as a food additive, in particular related to rebaudioside M produced via ...
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Karl‐Heinz Engel, Paul Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Rainer Gürtler, Ursula Gundert‐Remy, Trine Husøy, Wim Mennes, Peter Moldeus, Agneta Oskarsson, Romina Shah, Ine Waalkens‐Berendsen, Detlef Wölfle, Gisela Degen, David Gott, Jean‐Charles Leblanc, Lieve Herman, Jaime Aguilera, Alessandra Giarola, Ana M Rincon, Laurence Castle   +23 more
doaj   +1 more source