Results 71 to 80 of about 82,526 (233)

Exploring regulatory network of icariin synthesis in Herba Epimedii through integrated omics analysis

Frontiers in Plant Science
Herba Epimedii’s leaves are highly valued in traditional Chinese medicine for their substantial concentration of flavonoids, which play a crucial role in manifesting the plant’s therapeutic properties.
Xuedong Zhu, Shiqi Wen, Shiqi Wen, Hameed Gul, Pan Xu, Yang Yang, Yang Yang, Ximei Liao, Ximei Liao, Yunling Ye, Yunling Ye, Zijian Xu, Zijian Xu, Xiaofang Zhang, Lin Wu, Lin Wu, Lin Wu   +16 more
doaj   +1 more source

Safety of the proposed amendment of the specifications for steviol glycosides (E 960) as a food additive: Rebaudioside M produced via enzyme‐catalysed bioconversion of purified stevia leaf extract

EFSA Journal, 2019
The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of the proposed amendment of the specifications for steviol glycosides (E 960) as a food additive, in particular related to rebaudioside M produced via ...
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Karl‐Heinz Engel, Paul Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Rainer Gürtler, Ursula Gundert‐Remy, Trine Husøy, Wim Mennes, Peter Moldeus, Agneta Oskarsson, Romina Shah, Ine Waalkens‐Berendsen, Detlef Wölfle, Gisela Degen, David Gott, Jean‐Charles Leblanc, Lieve Herman, Jaime Aguilera, Alessandra Giarola, Ana M Rincon, Laurence Castle   +23 more
doaj   +1 more source

Exploring the significance of glycosylation in prostate cancer subtyping through single-cell analysis [PDF]

Journal of Men's Health
Prostate cancer impacts millions of men worldwide and causes significant disease burden. Glycosylation is the post-translational modification offering novel therapeutics for prostate cancer.
Shijun Tong, Wenhui Zhu, Jing Zhai, Guanxiong Ding   +3 more
doaj   +1 more source

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

UDP-N-Acetylglucosamine 4-Epimerase Activity Indicates the Presence of N-Acetylgalactosamine in Exopolysaccharides of Streptococcus thermophilus Strains [PDF]

, 2001
The monomer composition of the exopolysaccharides (EPS) produced by Streptococcus thermophilus LY03 and S. thermophilus Sfi20 were evaluated by high-pressure liquid chromatography with amperometric detection and nuclear magnetic resonance spectroscopy ...
Laws, Andrew P., Degeest, B., Vaningelgem, Frederik, De Vuyst, Luc   +3 more
core   +1 more source

MAPK Inhibitor‐Tolerant Persister Cells in Melanoma: Mechanisms and Therapeutic Vulnerabilities

Cancer Science, EarlyView.
Melanoma response to MAPK inhibition progresses from drug‐sensitive cells to drug‐tolerant persister states, which enable survival through adaptive signaling, metabolic rewiring, and phenotypic plasticity. These persister cells serve as an intermediate reservoir from which resistant tumors ultimately emerge. ABSTRACT Though major advancements have been
Bhoomi Shah, Mackenzie M. Mayhew, Jacob Sellers, Russell G. Witt   +3 more
wiley   +1 more source

O-glucosyltransferases in wheat (triticum aeshvum) and the competing weed black-grass (alopecurus myosuroides) [PDF]

, 2003
The glucosylation of xenobiotics, catalysed by UDP-glucose dependent O-Glucosyltransferases (OGTs), is a major route of pesticide metabolism in wheat {Triticum aestivum L.).
Brazier, Melissa Catherine
core  

Trypanosoma brucei UDP-glucose:glycoprotein glucosyltransferase has unusual substrate specificity and protects the parasite from stress [PDF]

, 2009
In this paper, we describe the range of N-linked glycan structures produced by wild-type and glucosidase II null mutant bloodstream form Trypanosoma brucei parasites and the creation and characterization of a bloodstream form Trypanosoma brucei UDP ...
Atrih, Abdel, Ferguson, Michael A. J.; id_orcid, Izquierdo, Luis, Jones, Deuan C., Rodrigues, Joao A.   +4 more
core   +1 more source

A nutrient-dependent division antagonist is regulated post-translationally by the Clp proteases in Bacillus subtilis

BMC Microbiology, 2018
Background Changes in nutrient availability have dramatic and well-defined impacts on both transcription and translation in bacterial cells. At the same time, the role of post-translational control in adaptation to nutrient-poor environments is poorly ...
Norbert S. Hill, Jason D. Zuke, P. J. Buske, An-Chun Chien, Petra Anne Levin   +4 more
doaj   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source