Results 81 to 90 of about 46,014 (199)

Structure of the UDP-Glucosyltransferase GtfB That Modifies the Heptapeptide Aglycone in the Biosynthesis of Vancomycin Group Antibiotics [PDF]

Structure, 2001
Members of the vancomycin group of glycopeptide antibiotics have an oxidatively crosslinked heptapeptide scaffold decorated at the hydroxyl groups of 4-OH-Phegly4 or beta-OH-Tyr6 with mono- (residue 6) or disaccharides (residue 4). The disaccharide in vancomycin itself is L-vancosamine-1,2-glucose, and in chloroeremomycin it is L-4-epi-vancosamine-1,2 ...
Mulichak, Anne M., Losey, Heather C., Walsh, Christopher T., Garavito, R.Michael   +3 more
openaire   +2 more sources

Biochemical and molecular characterization of a flavonoid 3-O-glycosyltransferase responsible for anthocyanins and flavonols biosynthesis in Freesia hybrida

Frontiers in Plant Science, 2016
The glycosylation of flavonoids increases their solubility and stability in plants. Flowers accumulate anthocyanidin and flavonol glycosides which are synthesized by UDP-sugar flavonoid glycosyltransferases (UFGTs).
Wei eSun, Wei eSun, Lingjie eLiang, Xiangyu eMeng, Yueqing eLi, Fengzhan eGao, Xingxue eLiu, Shucai eWang, Xiang eGao, Xiang eGao, Li eWang   +10 more
doaj   +1 more source

The Ecdysteroid UDP-Glucosyltransferase Gene Promoter from Autographa californica Multicapsid Nucleopolyhedrovirus

Zeitschrift für Naturforschung C, 2004
Abstract The ecdysteroid UDP-glucosyltransferase (egt) gene promoter fragments of different lengths were generated from the genomic DNA of the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) by PCR. After being purified and enzymatic digestion, they were cloned into the pGEM-3Z vector for construction of reporter ...
Xing-Jia, Shen, Yong-Zhu, Yi, Shun-Ming, Tang, Zhi-Fang, Zhang, Yi-Ren, Li, Jia-Lu, He   +5 more
openaire   +2 more sources

Transgenic Arabidopsis thaliana expressing a barley UDP-glucosyltransferase exhibit resistance to the mycotoxin deoxynivalenol [PDF]

Journal of Experimental Botany, 2012
Fusarium head blight (FHB), caused by Fusarium graminearum, is a devastating disease of small grain cereal crops. FHB causes yield reductions and contamination of grain with trichothecene mycotoxins such as deoxynivalenol (DON). DON inhibits protein synthesis in eukaryotic cells and acts as a virulence factor during fungal pathogenesis, therefore ...
Shin, Sanghyun, Torres-Acosta, Juan Antonio, Heinen, Shane J., McCormick, Susan, Lemmens, Marc, Paris, Maria Paula Kovalsky, Berthiller, Franz, Adam, Gerhard, Muehlbauer, Gary J.   +8 more
openaire   +2 more sources

UDP-glycosyltransferases alleviate the toxic effects of deoxynivalenol on the growth performance and gut damage of Kunming mice

Scientific Reports
The purpose of this study was to assess the effects of UDP-glycosyltransferases (UGTs) on alleviating the toxic effects of deoxynivalenol (DON) on Kunming mouse growth performance and gut damage.
Jiaxu Liu, Xue Ling, Zhaoquan Chen, Huajie Yang, Sitao Guo, Bingyang Zhou, Pengwei Zhu, Zheng Yang, Yongqiang Wang   +8 more
doaj   +1 more source

O-glucosyltransferases in wheat (triticum aeshvum) and the competing weed black-grass (alopecurus myosuroides) [PDF]

, 2003
The glucosylation of xenobiotics, catalysed by UDP-glucose dependent O-Glucosyltransferases (OGTs), is a major route of pesticide metabolism in wheat {Triticum aestivum L.).
Brazier, Melissa Catherine
core  

Effect of COMT and UGT1A Variants on Clinical Response to Opicapone in Parkinson's Disease

Movement Disorders Clinical Practice, Volume 13, Issue 10, Page 2517-2525, October 2026.
Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. Symptomatic treatment is based on dopaminergic replacement. With disease progression, the initial benefit of levodopa becomes inconsistent, and motor complications emerge.
Elena Ojeda‐Lepe, Sergio García‐Díaz, Laura Muñoz‐Delgado, Miguel Martín‐Bórnez, Silvia Jesús, Dolores Buiza‐Rueda, Marta Bonilla‐Toribio, Rafael Díaz‐Belloso, Daniel Macías‐García, Astrid Adarmes‐Gómez, Antonio Luque‐Ambrosiani, Rocío Pineda‐Sánchez, Lorena Clavijo‐Jiménez, Fátima Carrillo‐García, Pilar Gómez‐Garre, Pablo Mir   +15 more
wiley   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, Volume 49, Issue 10, Page 7558-7574, October 2026.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

Determinants and Expansion of Specificity in a Trichothecene UDP-Glucosyltransferase from Oryza sativa

Biochemistry, 2017
Family 1 UDP-glycosyltransferases (UGTs) in plants primarily form glucose conjugates of small molecules and, besides other functions, play a role in detoxification of xenobiotics. Indeed, overexpression of a barley UGT in wheat has been shown to control Fusarium head blight, which is a plant disease of global significance that leads to reduced crop ...
Karl M. Wetterhorn, Kaitlyn Gabardi, Herbert Michlmayr, Alexandra Malachova, Mark Busman, Susan P. McCormick, Franz Berthiller, Gerhard Adam, Ivan Rayment   +8 more
openaire   +3 more sources

Anthocyanins and betalains in evolution: Why mutual exclusion remains the best‐supported model

Plant Biology, Volume 28, Issue 6, Page 1763-1766, October 2026.
Anthocyanins and betalains are plant pigments produced through different biosynthetic pathways and are generally considered mutually exclusive. We examine claims of their co‐occurrence, arguing that methodological flaws and data misinterpretation have led to unsupported reports, and offer recommendations for more rigorous future research.
B. Pucker, M. I. Khan
wiley   +1 more source