Results 81 to 90 of about 35,038 (214)

UDP-Glucose Analogues as Inhibitors and Mechanistic Probes of UDP-Glucose Dehydrogenase

, 2016
UDP-glucose dehydrogenase catalyzes the NAD+-dependent 2-fold oxidation of UDP-glucose to give UDP-glucuronic acid. The putative aldehyde intermediate is not released from the active site and is presumably tightly bound.
Martin E. Tanner (1443997), Robert E. Campbell (112695)   +1 more
core   +1 more source

Biochemical and molecular characterization of a flavonoid 3-O-glycosyltransferase responsible for anthocyanins and flavonols biosynthesis in Freesia hybrida

Frontiers in Plant Science, 2016
The glycosylation of flavonoids increases their solubility and stability in plants. Flowers accumulate anthocyanidin and flavonol glycosides which are synthesized by UDP-sugar flavonoid glycosyltransferases (UFGTs).
Wei eSun, Wei eSun, Lingjie eLiang, Xiangyu eMeng, Yueqing eLi, Fengzhan eGao, Xingxue eLiu, Shucai eWang, Xiang eGao, Xiang eGao, Li eWang   +10 more
doaj   +1 more source

Bioconversion of carotenoids into high‐value crocins using a marine sponge carotenoid cleavage dioxygenase

New Phytologist, Volume 250, Issue 5, Page 3230-3246, June 2026.
Summary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Elena Moreno‐Giménez, Lucía Morote, Alberto José López Jiménez, Eduardo Parreño, Jian You Wang, Matteo Nava, Carolina Aguado, Rafael Luján, Salim Al‐Babili, Gianfranco Diretto, Oussama Ahrazem, Lourdes Gómez‐Gómez   +11 more
wiley   +1 more source

Determinants and Expansion of Specificity in a Trichothecene UDP-Glucosyltransferase from Oryza sativa

Biochemistry, 2017
Family 1 UDP-glycosyltransferases (UGTs) in plants primarily form glucose conjugates of small molecules and, besides other functions, play a role in detoxification of xenobiotics. Indeed, overexpression of a barley UGT in wheat has been shown to control Fusarium head blight, which is a plant disease of global significance that leads to reduced crop ...
Karl M. Wetterhorn, Kaitlyn Gabardi, Herbert Michlmayr, Alexandra Malachova, Mark Busman, Susan P. McCormick, Franz Berthiller, Gerhard Adam, Ivan Rayment   +8 more
openaire   +3 more sources

Identification and Characterization of DcUSAGT1, a UDP-Glucose: Sinapic Acid Glucosyltransferase from Purple Carrot Taproots. [PDF]

PLoS ONE, 2016
Purple carrots accumulate abundant cyanidin-based anthocyanins in taproots. UDP-glucose: sinapic acid glucosyltransferase (USAGT) can transfer the glucose moiety to the carboxyl group of sinapic acid thereby forming the ester bond between the carboxyl-C ...
Yi-Yun Chen, Zhi-Sheng Xu, Ai-Sheng Xiong   +2 more
doaj   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

Advanced Science, Volume 13, Issue 29, 22 May 2026.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu, Wenna Duan, Weiwei Tang, Yucheng Zhao, Bin Li   +4 more
wiley   +1 more source

Validation of a Candidate Deoxynivalenol-Inactivating UDP-Glucosyltransferase from Barley by Heterologous Expression in Yeast [PDF]

Molecular Plant-Microbe Interactions®, 2010
Resistance to the virulence factor deoxynivalenol (DON) due to formation of DON-3-O-glucoside (D3G) is considered to be an important component of resistance against Fusarium spp. which produce this toxin. Multiple candidate UDP-glycosyltransferase (UGT) genes from different crop plants that are either induced by Fusarium spp.
Adam, Gerhard, Schweiger, Wolfgang, Boddu, Jayanand, Shin, Sanghyun, Poppenberger-Sieberer, Brigitte, Berthiller, Franz, Lemmens, Marc, Muehlbauer, Gary J.   +7 more
openaire   +4 more sources

UDP-glycosyltransferases alleviate the toxic effects of deoxynivalenol on the growth performance and gut damage of Kunming mice

Scientific Reports
The purpose of this study was to assess the effects of UDP-glycosyltransferases (UGTs) on alleviating the toxic effects of deoxynivalenol (DON) on Kunming mouse growth performance and gut damage.
Jiaxu Liu, Xue Ling, Zhaoquan Chen, Huajie Yang, Sitao Guo, Bingyang Zhou, Pengwei Zhu, Zheng Yang, Yongqiang Wang   +8 more
doaj   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

UDP-MurNAc-pentapeptide synthesis.

, 2018
(A) The principle of the reaction where the amine group of the lysine in UDP-MurNAc-pentapeptide was converted to azide through diazo transfer. (B) Structure of dansyl alkyne.
Yao Liu (173014), Stefan Scheidelaar (1875211), J. Antoinette Killian (469726), Michal Heger (3574472), Elisabete C. C. M. Moura (5931875), Eefjan Breukink (154126), Jonas M. Dörr (5931878), Maarten R. Egmond (2095573), Tamimount Mohammadi (80891)   +8 more
core   +1 more source