Results 91 to 100 of about 72,405 (234)

Expression, purification & characterization of rat UDP-glucuronosyltransferase 1A8 [PDF]

, 2006
Lau San Shing.Thesis (M.Phil.)--Chinese University of Hong Kong, 2006.Includes bibliographical references (leaves 113-120).Abstracts in English and Chinese.Title Page --- p.1List of Thesis Committee --- p.2Declaration Page --- p.3Acknowledgements ---

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The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence

, 1991
A nomenclature system for the UDP glucuronosyltransferase superfamily is proposed, based on divergent evolution of the genes. A total of 26 distinct cDNAs in five mammalian species have been sequenced to date.
Lancet, D., Chowdhury, J. R., Jansen, P. L., Nebert, D. W., Nelson, D. R., Mulder, G. J., Iyanagi, T., Bock, K. W., Burchell, B., Siest, G.   +9 more
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The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis. [PDF]

Clin Pharmacokinet, 2023
Duthaler U, Bachmann F, Ozbey AC, Umehara K, Parrott N, Fowler S, Krähenbühl S.   +6 more
europepmc   +1 more source

The chemical modification of human liver UDP-glucuronosyltransferase UGT1*6 reveals the involvement of a carboxyl group in catalysis

, 1994
The treatment of UDP-glucuronosyltransferase UGT1*6 stably expressed in V79 cells with three car☐yl-specific reagents, dicyclohexylcarbodiimide, 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide andN-ethyl-5-phenylisoxazolium-3′-sulfonate (Woodward's ...
Magdalou, Jacques, Herber, Re´gine, Battaglia, Eric, Fournel-Gigleux, Sylvie, Siest, Ge´rard, Senay, Claire   +5 more
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Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences. [PDF]

Int J Mol Sci, 2023
Chen J, Qin L, Wu X, Tan D, Lu Y, Du Y, Wu D, He Y.   +7 more
europepmc   +1 more source

CHARACTERIZATION OF AFLOQUALONE N-GLUCURONIDATION: SPECIES DIFFERENCES AND IDENTIFICATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE ISOFORM(S)

, 2020
: Afloqualone (AFQ) is one of the centrally acting muscle relaxants. AFQ N-glucuronide is the most abundant metabolite in human urine when administered orally, whereas it was not detected in the urine when administered to rats, dogs, and monkeys. Species
Toshiyuki Kume, Hidefumi Kaji
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Selective induction of bilirubin UDP-glucuronosyl-transferase by perfluorodecanoic acid

, 1991
Differential effects of perfluorodecanoic acid (PFDA) on rat liver UDP-glucuronosyltransferase isoenzymes have been observed after a single i.p. administration of the compound to young male Sprague-Dawley rats. (1) Bilirubin glucuronidation was induced 2-
Oesch, F, Burchell, B, Robertson, L W, Arand, Michael; https://orcid.org/, Coughtrie, Michael W H   +4 more
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Establishment of the experimental procedure for prediction of conjugation capacity in mutant UGT1A1.

PLoS ONE, 2019
UDP-glucuronosyltransferase 1A1 (UGT1A1) is an enzyme that is found in the endoplasmic reticulum membrane and can reportedly have a large number of amino acid substitutions that result in the reduction of glucuronidation capacity.
Yutaka Takaoka, Atsuko Takeuchi, Aki Sugano, Kenji Miura, Mika Ohta, Takashi Suzuki, Daisuke Kobayashi, Takuji Kimura, Juichi Sato, Nobutaro Ban, Hisahide Nishio, Toshiyuki Sakaeda   +11 more
doaj   +1 more source

The Survival and Physiological Response of Calliptamus abbreviatus Ikonn (Orthoptera: Acrididae) to Flavonoids Rutin and Quercetin

Insects
Insect-resistant substances from plants are important natural resources that human beings can potentially develop and use to control pests. In this study, we explored the adverse effects of rutin and quercetin on grasshopper (Calliptamus abbreviatus), as
Xunbing Huang, Li Zheng, Yueyue Wang
doaj   +1 more source

Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter Polymorphisms among distinct ethnic groups from Brazil

, 2015
A polymorphism in the promoter region of the UDP-glucuronosyltransferase 1 (UGT1A) gene is associated with Gilbert syndrome (GS), a benign form of mild unconjugated hyperbilirubinemia.
Goncalves, MS, Fertrin, KY, Saad, STO, Costa, FF   +3 more
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