环境与职业医学BackgroundMaternal exposure to bisphenol A (BPA) during pregnancy is closely related to adverse growth and development conditions such as preterm birth and low birth weight, but the relevant mechanisms are still unclear.
Peili WANG +7 more
doaj +1 more source
Clinical Proteomics, 2011 Enzymes are critically important in the transportation, metabolism, and clearance of most therapeutic drugs used in clinical practice today. Many of these enzymes have significant genetic polymorphisms that affect the enzyme's rate kinetics.
Wu Alan HB
doaj +1 more source
The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis. [PDF]
Clin Pharmacokinet, 2023 Duthaler U +6 more
europepmc +1 more source
Chemoprevention of aberrant crypt foci in the colon of rats by dietary onion [PDF]
, 2007 Onion intake might reduce the risk of colorectal cancer, according to epidemiology. However, Femia showed in 2003 that diets with a 20% onion intake increase carcinogenesis in rats. We speculated this dose was too high.
Corpet, Denis E. +2 more
core +4 more sources
Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences. [PDF]
Int J Mol Sci, 2023 Chen J +7 more
europepmc +1 more source
A mutation which disrupts the hydrophobic core of the signal peptide of bilirubin UDP‐glucuronosyltransferase, an endoplasmic reticulum membrane protein, causes Crigler‐Najjar type IIs [PDF]
, 1996 Jurgen Seppen +4 more
openalex +1 more source
Functional expression of uridine diphospho glucuronosyltransferases in fission yeast [PDF]
, 2011 Uridine diphospho (UDP) glucuronosyltransferases (UGTs) catalyze the transfer of a sugar moiety from UDP-sugar to endogenous or exogenous compounds. The water solubility of these substances is increased thereby and their excretion from the human body is ...
Buchheit, Daniela
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Molecules, 2011 Corydaline is a bioactive alkaloid with various antiacetylcholinesterase, antiallergic, and antinociceptive activities found in the medicinal herb Corydalis Tubers.
Hyun Joo Shim +6 more
doaj +1 more source
Oligomerization of the UDP-glucuronosyltransferase 1A Proteins [PDF]
, 2006 Theresa N. Operaña, Robert H. Tukey
openalex +1 more source
Gilbert Syndrome and the Development of Antiretroviral Therapy-Associated Hyperbilirubinemia [PDF]
, 2017 BackgroundUnconjugated hyperbilirubinemia results from Gilbert syndrome and from antiretroviral therapy (ART) containing protease inhibitors. An understanding of the interaction between genetic predisposition and ART may help to identify individuals at ...
Bernasconi, Enos +9 more
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