Results 121 to 130 of about 57,370 (289)

Identification of UDP-Glucuronosyltransferase 2B15 (UGT2B15) as a Target for IGF1 and Insulin Action. [PDF]

Cells, 2022
Sarfstein R, Nagaraj K, Parikh S, Levy C, Laron Z, Benayahu D, Werner H.   +6 more
europepmc   +1 more source

Inhibition of UDP‐glucuronosyltransferase activity by possible transition‐state analogues in rat‐liver microsomes [PDF]

, 1990
Daan Noort, Michael W.H. Coughtrie, Brian Burchell, Gijs A. van der Marel, Jacques H. van Boom, Arne van der Gen, Gerard J. Mulder   +6 more
openalex   +1 more source

Establishment of the experimental procedure for prediction of conjugation capacity in mutant UGT1A1.

PLoS ONE, 2019
UDP-glucuronosyltransferase 1A1 (UGT1A1) is an enzyme that is found in the endoplasmic reticulum membrane and can reportedly have a large number of amino acid substitutions that result in the reduction of glucuronidation capacity.
Yutaka Takaoka, Atsuko Takeuchi, Aki Sugano, Kenji Miura, Mika Ohta, Takashi Suzuki, Daisuke Kobayashi, Takuji Kimura, Juichi Sato, Nobutaro Ban, Hisahide Nishio, Toshiyuki Sakaeda   +11 more
doaj   +1 more source

Intestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse Model. [PDF]

Drug Metab Dispos, 2022
Mennillo E, Yang X, Weber AA, Maruo Y, Verreault M, Barbier O, Chen S, Tukey RH.   +7 more
europepmc   +1 more source

The Survival and Physiological Response of Calliptamus abbreviatus Ikonn (Orthoptera: Acrididae) to Flavonoids Rutin and Quercetin

Insects
Insect-resistant substances from plants are important natural resources that human beings can potentially develop and use to control pests. In this study, we explored the adverse effects of rutin and quercetin on grasshopper (Calliptamus abbreviatus), as
Xunbing Huang, Li Zheng, Yueyue Wang
doaj   +1 more source

UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes [PDF]

, 2015
Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu, Zhongqiu Liu   +9 more
openalex   +1 more source

A hypothesis on the equilibrium between dopamine toxicity and detoxification: The roles of NQO2 and UDP-glucuronosyltransferases

, 2023
Jean A. Boutin, Gilles Ferry, Karine Reybier   +2 more
openalex   +1 more source

Stereoselective Covalent Adduct Formation of Acyl Glucuronide Metabolite of Nonsteroidal Anti-Inflammatory Drugs with UDP-Glucuronosyltransferase. [PDF]

Int J Mol Sci, 2022
Kawase A, Yamashita R, Yoshizato T, Yoshikawa M, Shimada H, Iwaki M.   +5 more
europepmc   +1 more source

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.

New England Journal of Medicine, 1995
P. Bosma, J. Chowdhury, C. Bakker, S. Gantla, A. Boer, B. Oostra, D. Lindhout, G. Tytgat, P. Jansen, R. P. Elferink, N. Chowdhury   +10 more
semanticscholar   +1 more source

Relationship of circulating total bilirubin, UDP-glucuronosyltransferases 1A1 and the development of non-alcoholic fatty liver disease: a cross-sectional study [PDF]

, 2022
Xuefeng Ma, Zheng Xu, Shousheng Liu, Likun Zhuang, Mengke Wang, Yifen Wang, Yongning Xin, Shiying Xuan   +7 more
openalex   +1 more source