Results 141 to 150 of about 68,086 (202)

Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs

Drug Metabolism Reviews, 2022
The human UGT gene superfamily is divided into four subfamilies (UGT1, UGT2, UGT3 and UGT8) that encodes 22 functional enzymes. UGTs are critical for the metabolism and clearance of numerous endogenous and exogenous compounds, including steroid hormones,
Dong Gui Hu   +2 more
exaly   +4 more sources

Functional analysis of UDP-glycosyltransferase genes conferring indoxacarb resistance in Spodoptera litura

Pesticide Biochemistry and Physiology, 2023
UDP-glycosyltransferase (UGT) is the major detoxification enzymes of phase II involved in xenobiotics metabolism, which potentially mediates the formation of insect resistance.
Li Shi
exaly   +2 more sources

One-pot biosynthesis of gastrodin using UDP-glycosyltransferase itUGT2 with an in situ UDP-glucose recycling system

Enzyme and Microbial Technology, 2023
Gastrodin, the major effective ingredient in Tianma (Gastrodia elata), is a p-hydroxybenzoic acid derivative with various activities. Gastrodin has been widely investigated for food and medical applications. The last biosynthetic step for gastrodin is UDP-
Caixia Cui, Yongtao Liu
exaly   +2 more sources

Engineering of a UDP-Glycosyltransferase for the Efficient Whole-Cell Biosynthesis of Siamenoside I in Escherichia coli

Journal of Agricultural and Food Chemistry, 2022
The combination of the insufficient availability and the complex structure of siamenoside I (SI), the sweetest glucoside isolated from Siraitia grosvenorii to date, limited its use as a natural sweetener.
Shiqiang Liu, Chen Luo, Yijun Chen
exaly   +2 more sources

Salidroside production through cascade biocatalysis with a thermostability-enhanced UDP-glycosyltransferase.

International Journal of Biological Macromolecules
Salidroside is a phenylpropanoid glycoside with wide applications in the food, pharmaceutical, and cosmetic industries; however, the plant genus Rhodiola, the natural source of salidroside, has slow growth and limited distribution.
Guosi Li   +8 more
semanticscholar   +3 more sources

Comparative analysis of the UDP-glycosyltransferase multigene family in insects

Insect Biochemistry and Molecular Biology, 2012
UDP-glycosyltransferases (UGT) catalyze the conjugation of a range of diverse small lipophilic compounds with sugars to produce glycosides, playing an important role in the detoxification of xenobiotics and in the regulation of endobiotics in insects.
Seung-Joon Ahn   +2 more
exaly   +4 more sources

Over-expression of UDP-glycosyltransferase UGT353G2 confers resistance to neonicotinoids in whitefly (Bemisia tabaci).

Pesticide Biochemistry and Physiology, 2023
The whitefly, Bemisia tabaci, comes up high metabolic resistance to most neonicotinoids in long-term evolution, which is the key problem of pest control.
Tian-hua Du   +19 more
semanticscholar   +1 more source

Contribution of UDP-glycosyltransferases to chlorpyrifos resistance in Nilaparvata lugens

Pesticide Biochemistry and Physiology, 2023
As a multigene superfamily of Phase II detoxification enzymes, uridine diphosphate (UDP)-glycosyltransferases (UGTs) play important roles in the metabolism of xenobiotics including insecticides. In this study, 5-nitrouracil, an inhibitor of UGT enzyme activity, effectively increased the toxicity of chlorpyrifos to the chlorpyrifos-resistant strain of ...
Zhiming, Yang, Tianxiang, Xiao, Kai, Lu
openaire   +2 more sources

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