Results 151 to 160 of about 68,086 (202)

Glycosylation of Secondary Metabolites: A Multifunctional UDP-Glycosyltransferase, CsUGT74Y1, Promotes the Growth of Plants.

Journal of Agricultural and Food Chemistry, 2023
Camellia sinensis contains numerous glycosylated secondary metabolites that provide various benefits to plants and humans. However, the genes that catalyze the glycosylation of multitype metabolites in tea plants remain unclear.
Changli Yang, Fengyun Tian, Jie Ma, Mei Chen, Xingxing Shi, Dingli Chen, Youshudi Xie, Xingrong Zhou, Zhi Zhou, Xinlong Dai, Tao Xia, Liping Gao   +11 more
semanticscholar   +1 more source

Identification and characterization of UDP-Glycosyltransferase genes and the potential role in response to insecticides exposure in Bactrocera dorsalis.

Pest Management Science, 2022
BACKGROUND The oriental fruit fly, Bactrocera dorsalis (Hendel) is a worldwide pest damaging a wide range of hosts. Due to the long-term indiscriminate use of insecticides, B. dorsalis has developed serious resistance to several insecticides.
Mengling Chen, Shu-Xia Zhang, P. Guo, Qing-Shi Qin, Li-Wei Meng, Guorui Yuan, Jinjun Wang   +6 more
semanticscholar   +1 more source

Inhibition of hepatocyte nuclear factor 4 confers imidacloprid resistance in Nilaparvata lugens via the activation of cytochrome P450 and UDP-glycosyltransferase genes.

Chemosphere, 2021
Increasing evidence indicates that insect resistance to synthesized insecticides is regulated by the nuclear receptors. However, the underlying mechanisms of this regulation are not clear. Here, we demonstrate that inhibition of hepatocyte nuclear factor
Yibei Cheng, Yimin Li, Wenru Li, Yuanyuan Song, R. Zeng, K. Lu   +5 more
semanticscholar   +1 more source

Triterpenoid-biosynthetic UDP-glycosyltransferases from plants

Biotechnology Advances, 2019
Triterpenoid saponins are naturally occurring structurally diverse glycosides of triterpenes that are widely distributed among plant species. Great interest has been expressed by pharmaceutical and agriculture industries for the glycosylation of triterpenes.
Shadi Rahimi, Jaewook Kim, Ivan Mijakovic, Ki-Hong Jung, Giltsu Choi, Sun-Chang Kim, Yu-Jin Kim   +6 more
openaire   +2 more sources

A Novel Function for UDP Glycosyltransferase 8: Galactosidation of Bile Acids

Molecular Pharmacology, 2015
The human UDP glycosyltransferase (UGT) superfamily comprises four families of enzymes that catalyze the addition of sugar residues to small lipophilic chemicals. The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conjugate xenobiotics, including drugs and endobiotics such as ...
Robyn Meech, Pramod C Nair, Dong Gui Hu
exaly   +3 more sources

Functional validation of key cytochrome P450 monooxygenase and UDP-glycosyltransferase genes conferring cyantraniliprole resistance in Aphis gossypii Glover.

Pesticide Biochemistry and Physiology, 2021
Cytochrome P450 monooxygenases (P450s) and UDP-glycosyltransferases (UGTs) are major detoxifying enzymes that metabolize plant toxins and insecticides.
Xiaochun Zeng, Yiou Pan, Fayi Tian, Jianyi Li, Hongfei Xu, Xuemei Liu, Xuewei Chen, Xiwu Gao, T. Peng, Rui Bi, Q. Shang   +10 more
semanticscholar   +1 more source

UGT3A: novel UDP-glycosyltransferases of the UGT superfamily

Drug Metabolism Reviews, 2009
Mammalian UDP-glycosyltransferases (UGTs) are divided into four families: UGT1, UGT2, UGT3, and UGT8. UGT3 is the last of the gene families to be identified, and until relatively recently, little was known about the function of these enzymes. In this article, we present new analyses of the UGT3 family genes, including the structure of the UGT3A locus ...
Mackenzie, Peter Ian, Meech, Robyn
openaire   +3 more sources

The UDP-glycosyltransferase UGT352A3 contributes to the detoxification of thiamethoxam and imidacloprid in resistant whitefly.

Pesticide Biochemistry and Physiology
Uridine diphosphate (UDP)-glycosyltransferases are essential phase-II detoxification enzymes that glycosylate lipophilic endogenous and xenobiotic compounds and they are thought to play a role in driving the evolution of insecticide resistance.
T. Du, Hu Xue, Xiaomao Zhou, Lianyou Gui, Natalia Belyakova, Youjun Zhang, Xin Yang   +6 more
semanticscholar   +1 more source

Structural, Functional, and Mutagenesis Studies of UDP-Glycosyltransferases

2012
The biosynthesis of the complex carbohydrates that govern many cellular functions requires the action of a diverse range of selective glycosyltransferases (GTs). Uridine diphosphate sugar-utilizing GTs (UGTs) account for the majority of characterized GTs.
Vatsala, Malik, Gary W, Black
openaire   +2 more sources

UDP-glycosyltransferases contribute to the tolerance of parasitoid wasps towards insecticides

Pesticide Biochemistry and Physiology, 2021
Meteorus pulchricornis (Wesmael) (Hymenoptera: Braconidae) is a predominant endoparasitoid of lepidopteran pests in mulberry fields. Extensive application of insecticides puts natural enemies under threat. UDP-glycosyltransferases (UGTs), as important detoxification enzymes, potentially contribute to the detoxification of pesticides in insects.
Meng-Wen, Yan, Xiao-Rong, Xing, Fu-An, Wu, Jun, Wang, Sheng, Sheng   +4 more
openaire   +2 more sources