Results 181 to 190 of about 44,652 (214)

UDP-glycosyltransferases contribute to spirotetramat resistance in Aphis gossypii Glover

Pesticide Biochemistry and Physiology, 2020
Uridine diphosphate (UDP)-glycosyltransferases (UGTs) catalyze the conjugation of small lipophilic endogenous and exogenous compounds with sugars to produce water-soluble glycosides, playing an important role in insect endobiotic regulation and xenobiotic detoxification. In this study, two UGT-inhibitors, sulfinpyrazone and 5-nitrouracil, significantly
Yiou, Pan, Shuyuan, Wen, Xuewei, Chen, Xiwu, Gao, Xiaochun, Zeng, Xuemei, Liu, Fayi, Tian, Qingli, Shang   +7 more
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Insect UDP-glycosyltransferases and xenobiotic metabolism

Pesticide Biochemistry and Physiology
UDP-glycosyltransferases (UGTs) are a superfamily of enzymes ubiquitously found in virtually all organisms. They catalyze the addition of sugars from UDP-sugar donors that greatly enhance the water solubility of molecules, facilitating excretion. There are 10-76 Ugts in different insect species, and the last decade has seen a remarkable increase in ...
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Contribution of UDP-glycosyltransferases to clothianidin resistance in Bradysia odoriphaga

Pesticide Biochemistry and Physiology
Uridine diphosphate glycosyltransferases (UGTs) play critical roles in xenobiotic detoxification and are involved in insecticide resistance. In this study, UGT inhibitors, sulfinpyrazone and 5-nitrouracil, exhibited significant synergistic effects on clothianidin in the clothianidin-resistant strain (CL-R) of Bradysia odoriphaga. UGT enzyme content was
Chunni, Zhang, Ruifang, Liu, Xianglong, Chen, Xianling, Du, Shiying, Tang, Wu, Dai   +5 more
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Perinatal Development of Bilirubin UDP-Glycosyltransferase Activities in Rat Liver

Biology of the Neonate, 2009
Bilirubin UDP-glucuronyltransferase and UDP-xylosyltransferase activity could already be demonstrated in rat liver from day 19 of fetal life onwards (4 days before birth). Bilirubin-glucuronide was present in hepatocytes of 21-day-old fetal liver strongly suggesting that the enzyme detected in vitro was really active in vivo.
J, Fevery, C, De Wolf-Peeters, R, De Vos, V, Desmet, K P, Heirwegh   +4 more
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Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

Pharmacogenetics and Genomics, 2005
Several novel UDP glycosyltransferase (UGT) genes, mainly UDP glucuronosyltransferases, have been identified in the human, mouse and rat genomes and in other mammalian species. This review provides an update of the UGT nomenclature to include these new genes and prevent the confusion that arises when the same gene is given different names.
Burchell, Brian, Guillemette, Chantal, Iyanagi, T, Miners, John Oliver, Owens, Ida S, Nerbert, Daniel W, Ikushiro, S, Mackenzie, Peter Ian, Bock, Karl Walter   +8 more
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Enzymatic synthesis of novel corylifol A glucosides via a UDP-glycosyltransferase

Carbohydrate Research, 2017
Corylifol A, a member of the isoflavone subclass of isoflavonoids, has long been considered to have various biological activities. Here, we sought to synthesize corylifol A glucosides by the in vitro glucosylation reaction using the UDP-glycosyltransferase YjiC from Bacillus licheniformis DSM 13, and obtained two novel glucosides: corylifol A-4',7-di-O-
Nan Li, Jian Miao, Jing Li, Yu-Ru Zhao, Hong-Mei Li, Yi-Qun Dai, Qiang Huo, Cheng-Zhu Wu, Tao Ma   +8 more
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Metabolic detoxification of capsaicin by UDP‐glycosyltransferase in three Helicoverpa species

Archives of Insect Biochemistry and Physiology, 2011
AbstractCapsaicin β‐glucoside was isolated from the feces of Helicoverpa armigera, Helicoverpa assulta, and Helicoverpa zea that fed on capsaicin‐supplemented artificial diet. The chemical structure was identified by NMR spectroscopic analysis as well as by enzymatic hydrolysis.
Ahn, S., Badenes-Pérez, F., Reichelt, M., Svatoš, A., Schneider, B., Gershenzon, J., Heckel, D.   +6 more
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Drosophila Cellular Immune System: Dorothy Encodes a UDP Glycosyltransferase

2001
Immune defense in Drosophila has humoral and cellular components that act effectively to control infectious organisms through the production of antimicrobial proteins and the phagocytosis and encapsulation of invading organisms (reviewed in 9). The main tissue of humoral immune defense is the fat body, which corresponds to the mammalian liver. Cellular
Z, Zhou, A, Rodriguez, C Y, Wu, D A, Kimbrell   +3 more
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Structure function relationships in plant UDP-glycosyltransferases

Industrial Crops and Products, 2022
Jinbo Yao, Xiaowen Xing, Luyao Yu, Yun Wang, Xinfeng Zhang, Lei Zhang   +5 more
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Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs

Drug Metabolism Reviews, 2022
Peter I Mackenzie, Ross A. McKinnon, Dong Gui Hu   +2 more
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