Results 81 to 90 of about 60,978 (228)

Integrated proteomic and metabolomic analysis reveals that rhodomyrtone reduces the capsule in Streptococcus pneumoniae

Scientific Reports, 2017
The emergence of antibiotic-resistant pathogenic bacteria is a healthcare problem worldwide. We evaluated the antimicrobial activity of rhodomyrtone, an acylphloroglucinol present in Rhodomyrtus tomentosa leaves, against the human Gram-positive pathogen ...
Watcharapong Mitsuwan, Alfonso Olaya-Abril, Mónica Calderón-Santiago, Irene Jiménez-Munguía, José Antonio González-Reyes, Feliciano Priego-Capote, Supayang P. Voravuthikunchai, Manuel J. Rodríguez-Ortega   +7 more
doaj   +1 more source

Engineering of the Flavone Rutinoside Biosynthetic Pathway Enables Production of Diosmin, a Venoactive Compound in Solanum lycopersicum and Nicotiana tabacum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Diosmin is often used as a dietary supplement, and it is sometimes used to make phlebotropic drugs for venous diseases. Traditionally, diosmin is obtained by the dehydrogenation of the flavanone glycoside hesperidin through chemical semisynthesis.
Qianle Zhang, Qingwen Wu, Wenjing Shi, Yinai Deng, Ruoting Zhan, Dongming Ma   +5 more
wiley   +1 more source

Genome and Single‐Cell Transcriptome Reveal the Evolution of Holoparasitic Plants: A Case Study of Cistanche deserticola

Plant Biotechnology Journal, EarlyView.
ABSTRACT The Orobanchaceae family, the largest group of parasitic plants, spans a complete spectrum from autotrophic to holoparasitic species. As a typical endangered holoparasitic species within this family, Cistanche deserticola is a parasitic plant that is widely harvested for traditional medicine in desertic regions, and of growing importance as a ...
Xinke Zhang, Yujing Miao, Yuanyuan Xing, Guoshuai Zhang, Meiqiao Zhang, Chris J. Thorogood, Shilin Chen, Linfang Huang   +7 more
wiley   +1 more source

Phylogenetic Analysis of the UDP-glycosyltransferase Multigene Family of Arabidopsis thaliana [PDF]

Journal of Biological Chemistry, 2001
A class of UDP-glycosyltransferases (UGTs) defined by the presence of a C-terminal consensus sequence is found throughout the plant and animal kingdoms. Whereas mammalian enzymes use UDP-glucuronic acid, the plant enzymes typically use UDP-glucose in the transfer reactions. A diverse array of aglycones can be glucosylated by these UGTs.
Y, Li, S, Baldauf, E K, Lim, D J, Bowles
openaire   +2 more sources

Identification of a Flavonoid Glucosyltransferase Involved in 7-OH Site Glycosylation in Tea plants (Camellia sinensis)

Scientific Reports, 2017
Flavonol glycosides, which are often converted from aglycones in a process catalyzed by UDP-glycosyltransferases (UGTs), play an important role for the health of plants and animals.
Xinlong Dai, Juhua Zhuang, Yingling Wu, Peiqiang Wang, Guifu Zhao, Yajun Liu, Xiaolan Jiang, Liping Gao, Tao Xia   +8 more
doaj   +1 more source

Functional Differentiation of Duplicated Flavonoid 3-O-Glycosyltransferases in the Flavonol and Anthocyanin Biosynthesis of Freesia hybrida

Frontiers in Plant Science, 2019
Flavonols and anthocyanins are two widely distributed groups of flavonoids that occurred apart during plant evolution and biosynthesized by shared specific enzymes involved in flavonoid metabolism.
Xiangyu Meng, Yueqing Li, Tongtong Zhou, Wei Sun, Wei Sun, Xiaotong Shan, Xiang Gao, Xiang Gao, Li Wang   +8 more
doaj   +1 more source

Convergent Evolution and De Novo Reconstitution of Apiin Biosynthesis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Apiin, an active flavonoid apioside, occurs in phylogenetically distant plants, such as parsley and chilli pepper (Capsicum annuum L.). Its sporadic distribution suggests the existence of convergent apiin biosynthesis; however, the molecular mechanisms underlying this convergence remain unclear.
Zhen Xu, Zheng‐Shuang Zhu, Hai‐Zhu Jia, Jian‐Qiang Kong   +3 more
wiley   +1 more source

UGT85A84 Catalyzes the Glycosylation of Aromatic Monoterpenes in Osmanthus fragrans Lour. Flowers

Frontiers in Plant Science, 2019
The monoterpenes linalool and its oxides are the key aroma-active compounds in Osmanthus fragrans Lour. flowers. The glycosides of these monoterpenes accumulate throughout flowering, leading to considerable storage of potential aroma constituents that ...
Riru Zheng, Riru Zheng, Zhenyin Zhu, Zhenyin Zhu, Yanli Wang, Yanli Wang, Shiyang Hu, Shiyang Hu, Wan Xi, Wan Xi, Wei Xiao, Wei Xiao, Xiaolu Qu, Xiaolu Qu, Linlin Zhong, Linlin Zhong, Qiang Fu, Qiang Fu, Caiyun Wang, Caiyun Wang   +19 more
doaj   +1 more source

Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim, Keunhwa Kim, Jung Heo, Seung Mo Seo, Sungjun Choung, Hyeonjin Kim, Yuri Choi, Kyungsun Park, Hyejung Yun, Dongha Kim, Eun Song Lee, Junwoo Lee, Smita Mirsyad Warsadiharja, Saet Buyl Lee, Sunkyu Han, Soon Ju Park, Sang‐Gyu Kim   +16 more
wiley   +1 more source

Human Proteoglycan Linkage Region Glycosyltransferases are Dimeric and Show Unexpected Specificities

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Non‐canonical glycopeptides of the proteoglycan linkage region are accessible by the enzymes B3GalT6 and GlcAT‐1 confirming a recently discovered rescue mode in glycosaminoglycan (GAG) biosynthesis. The crystal structure of B3GalT6 revealed a covalent dimer linked by a disulfide. Abstract We selected the N,O‐glycosylated proteoglycan bikunin as a model
Sascha Weidler, Ole Bundgaard, Markus Hessefort, Marisa Rädisch, Christopher Günther Franz Graf, Kevin Lam, Vanessa J. Neubauer, Johanna Eisenreich, Leonhard Köhler, Kelley W. Moremen, Catharina Steentoft, Henrik Clausen, Teng‐Yi Huang, Shang‐Cheng Hung, Clemens Steegborn, Michael Weyand, Carlo Unverzagt   +16 more
wiley   +2 more sources