Results 31 to 40 of about 2,141 (127)

Association of UDP-galactose-4-epimerase with milk protein concentration in the Chinese Holstein population

Asian-Australasian Journal of Animal Sciences, 2020
Objective An initial RNA-Sequencing study revealed that UDP-galactose-4-epimerase (GALE) was one of the most promising candidates for milk protein concentration in Chinese Holstein cattle.
Cong Li, Wentao Cai, Shuli Liu, Chenghao Zhou, Mingyue Cao, H. Yin, D. Sun, Shengli Zhang, J. Loor   +8 more
semanticscholar   +1 more source

Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction

Journal of Biological Chemistry, 2020
UDP-glucuronic acid is converted to UDP-galacturonic acid en route to a variety of sugar-containing metabolites. This reaction is performed by a NAD+-dependent epimerase belonging to the short-chain dehydrogenase/reductase family. We present several high-
L. Iacovino, S. Savino, Annika J. E. Borg, C. Binda, B. Nidetzky, A. Mattevi   +5 more
semanticscholar   +1 more source

The structure-function relationships of maize starch synthase [PDF]

, 2001
This research was to study the structure-function relationships and catalytic mechanisms of maize starch synthase IIa (SSIIa). Chemical modification of maize SSIIa showed that pyridoxal-5-phosphate, which specifically modifies lysine residues ...
Gao, Zhong
core   +3 more sources

Genome-Wide Proteomics and Quantitative Analyses on Halophilic Archaea [PDF]

, 2008
The aerobic, haloalkaliphilic archaeon Natronomonas pharaonis is able to survive in salt-saturated lakes of pH 11. With genome-wide shotgun proteomics, 886 soluble proteins (929 proteins in total) of the theoretical Natronomonas pharaonis soluble ...
Konstantinidis, Konstantinos
core  

A Bifunctional UDP-Sugar 4-Epimerase Supports Biosynthesis of Multiple Cell Surface Polysaccharides in Sinorhizobium meliloti

Journal of Bacteriology, 2019
Bacterial extracellular polysaccharides serve important cell protective, structural, and signaling roles. They have particularly attracted attention as adhesives and matrix components promoting biofilm formation, which significantly contributes to ...
Simon Schäper, H. Wendt, Jan Bamberger, V. Sieber, J. Schmid, A. Becker   +5 more
semanticscholar   +1 more source

Developing the WCRF International/University of Bristol methodology for identifying and carrying out systematic reviews of mechanisms of exposure-cancer associations [PDF]

, 2017
Background: Human, animal, and cell experimental studies; human biomarker studies; and genetic studies complement epidemiologic findings and can offer insights into biological plausibility and pathways between exposure and disease, but methods for ...
Borwick, Catherine, Emmett, Pauline, Gardner, Mike, Gaunt, Tom, Harrison, Sean, Higgins, Julian, Holly, Jeff M. P., Jeffreys, Mona, Lennon, Rosie, Lewis, Sarah, Martin, Richard, Mitrou, Giota, Northstone, Kate, Perks, Claire, Rinaldi, Sabina, Tan, Vanessa, Thomas, Steve, Thompson, Rachel, Turner, Suzanne, Wiseman, Martin   +19 more
core   +2 more sources

Integrating highly quantitative proteomics and genome-scale metabolic modeling to study pH adaptation in the human pathogen Enterococcus faecalis [PDF]

, 2016
Genome-scale metabolic models represent the entirety of metabolic reactions of an organism based on the annotation of the respective genome. These models commonly allow all reactions to proceed concurrently, disregarding the fact that at no point all ...
Aebersold, Ruedi, Bergmann, Frank, Collins, Ben C, Fiedler, Tomas, Großeholz, Ruth, Koh, Ching-Chiek, Kreikemeyer, Bernd, Kummer, Ursula, Olivier, Brett, Schubert, Olga T, Strauss, Madlen, Veith, Nadine   +11 more
core   +1 more source

IN SILICO ANALYSIS OF MOMORDICA CHARANTIA L. AS ANTIDIABETIC AGENTS THROUGH ACTIVATION OF HUMAN UDP-GALACTOSE 4-EPIMERASE RECEPTORS

Media Farmasi
This study investigates the antidiabetic potential of compounds found in Momordica charantia L., commonly known as bitter melon, through molecular docking and ADME (Absorption, Distribution, Metabolism, and Excretion) analysis.
Analisa In-Silico, Momordica charantia, L. Sebagai, Senyawa Antidiabetes, Melalui Aktivasi, Reseptor UDP-Galactose, 4-Epimerase Manusia, Asri Dwi, Endah Dewi Pramesthi, Aldo Pratama¹, Jamiatur Rasyidah¹, Endah Dewi, Wayan Surya, Rima Rasida   +13 more
semanticscholar   +1 more source

Spaceflight Enhances Cell Aggregation and Random Budding in Candida albicans [PDF]

, 2013
: This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen, Candida albicans, grown in spaceflight conditions. Microarray analysis revealed that C.

core   +1 more source

Interplay of structural preorganization and conformational sampling in UDP-glucuronic acid 4-epimerase catalysis

Nature Communications
Understanding enzyme catalysis as connected to protein motions is a major challenge. Here, based on temperature kinetic studies combined with isotope effect measurements, we obtain energetic description of C-H activation in NAD-dependent UDP-glucuronic ...
Christian Rapp, Annika J E Borg, Bernd Nidetzky   +2 more
semanticscholar   +1 more source