Results 31 to 40 of about 65,761 (163)

Synthesis of 5 H -Pyrrolo[3,4- b ]Pyridin-5-Ones via a Cerium Chloride Catalyzed Multicomponent Cascade Process: A One-Pot Approach Incorporating Ugi-Zhu 3CR, Aza Diels–Alder, N -Acylation, and Aromatization Reactions

Polycyclic Aromatic Compounds
We have synthesized α-isocyano-β-phenylpropionamides 5 (a–c) using a two-step process and then created a new series of poly-substituted 5H-pyrrolo[3,4-b]pyridin-5-ones 12 (a–o) via a multi-component reaction. Most of the reported literature used scandium triflate and either benzene or toluene as solvents, which are not good for the environment. We have
Ramasamy Duraisamy, M. B. Madhusudana Reddy, I. V. Asharani, Dhakshanamurthy Thirumalai   +3 more
openaire   +2 more sources

Diastereoselective three-component synthesis of beta-amino carbonyl compounds using diazo compounds, boranes, and acyl imines under catalyst-free conditions [PDF]

, 2014
Diazo compounds, boranes, and acyl imines undergo a three-component Mannich condensation reaction under catalyst-free conditions to give the anti β-amino carbonyl compounds in high diastereoselectivity.
Luan, Yi, Schaus, Scott E., Wang, Ge, Yu, Jie, Zhang, Xiaowei   +4 more
core   +1 more source

Silver(I) triflate-catalyzed protocol for the post-ugi synthesis of spiroindolines

, 2019
A silver(I) triflate-catalyzed protocol for the post-Ugi synthesis of tetracyclic spiroindolines has been developed. The protocol worked best for indole-3-carbaldehyde-derived Ugi adducts obtained using anilines and 3-aryl propiolic acids.
Hasan, Muhammad, Pereshivko, Olga P., Peshkov, Anatoly A., Peshkov, Vsevolod A., Van der Eycken, Erik V., Van Hecke, Kristof, Zaman, Manzoor   +6 more
core   +1 more source

7,7′-(1,4-Phenylene)bis(2-benzyl-3-(3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one)

Molbank
The multicomponent synthesis of a novel and highly symmetric polyheterocycle based on the pyrrolo[3,4-b]pyridin-5-one core incorporating the privileged tetrahydroisoquinoline moiety is described.
Roberto E. Blanco-Carapia, Alejandro Islas-Jácome, Eduardo González-Zamora   +2 more
doaj   +1 more source

Ionic-Liquid-Supported Synthesis of Amines and Derivatives [PDF]

, 2006
International audienceAmine precursors such as glycines protected at nitrogen with a Boc or formyl group were grafted by esterification on the hydroxylated arms of 1-(2-hydroxyethyl)-3-methylimidazolium hexafluorophosphates or tetrafluoroborates.
Bazureau, J.P., Debdab, Mansour, Mongin, Florence   +2 more
core   +4 more sources

Studies on the Synthesis of DMAP Derivatives by Diastereoselective Ugi Reactions [PDF]

, 2011
Diastereoselective Ugi reactions of DMAP-based aldehydes with α-amino acids and tert-butyl isocyanide were examined. The reactions of 4-(dimethylamino)-2-pyridine-carboxaldehyde with various α-amino acids afforded 2-substituted DMAP derivatives with low ...
Irie, Shunsuke, Mandai, Hiroki, Mitsudo, Koichi, Suga, Seiji   +3 more
core   +3 more sources

Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides [PDF]

, 2014
Catalytic asymmetric 1,3-dipolar cycloadditions of azomethine ylides have turned out to be one of the most efficient methods for the preparation of enantioenriched pyrrolidines.
Adrio, Javier, Carretero, Juan C.
core   +2 more sources

Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles

, 2011
International audiencePyrazolidinones were prepared in a two-step sequence starting from a-hydrazonocarboxylic acids. After a four-component Ugi coupling, the resulting hydrazone was engaged in a copper triggered [3 + 2] cycloaddition/aerobic oxidation ...
dos Santos, Aurélie, El Kaim, Laurent, Grimaud, Laurence, Ronsseray, Caroline   +3 more
core   +5 more sources

Synthesis of Boron-Containing Primary Amines [PDF]

, 2013
[[abstract]]In this study, boron-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the first step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl
Baxter, Bódis, Chia-Hua Tsai, Hara, Po-Shen Pan, Qian-Yu Hu, Sheng-Hsuan Chung, Ting-Ju Lin, Tripathi   +8 more
core   +2 more sources

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

BMEMat, Volume 3, Issue 4, December 2025.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang, Yefei Dai, Yujun Hou, Joshua Stein, Shichen Steven Lin, Chaochen Zhou, Yannan Hou, Rongrong Zhu, Ki‐Bum Lee, Letao Yang   +9 more
wiley   +1 more source