Results 51 to 60 of about 65,761 (163)

UEG Week 2023 Poster Presentations

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 535-1498, October 2023.
wiley   +1 more source

Enantioselective main group catalysis: modern catalysts for organic transformations [PDF]

, 2016
This review highlights a number of recent developments in the field of main group enantioselective catalysis. Many essential transformations can be effected catalytically such as hydrosilylation, hydroamination and hydrogenation reactions, amongst others,
Melen, Rebecca L., Wilkins, Lewis C.
core   +1 more source

Total Synthesis of Discobahamin A and Putative Structure of Discobahamin B via an Isocyanide‐based Macrocyclization Reaction

Angewandte Chemie International Edition, Volume 64, Issue 10, March 3, 2025.
An isocyanide‐based macrocyclization, involving the formation of a C(sp3)‐C(sp2) bond and the concurrent generation of an α‐acyloxy amide functional group, has been developed and successfully applied to the total synthesis of discobahamin A, a 24‐membered macrocyclopeptide. Abstract We report in this paper the first total synthesis of discobahamin A, a
Baochao Yang, Qian Wang, Jieping Zhu
wiley   +1 more source

Recent Applications of Sulfonium Salts in Synthesis and Catalysis

Chemistry – A European Journal, Volume 30, Issue 70, December 13, 2024.
This review summarizes the recent developments on the synthetic applications of sulfonium salts with an emphasis on the description of the operating mechanistic pathways. Abstract The use of sulfonium salts in organic synthesis has experienced a dramatic increase during the last years that can arguably be attributed to three main factors; the ...
Sven Timmann, Zeyu Feng, Manuel Alcarazo
wiley   +1 more source

Genome-editing based engineering of CESA3 dual cellulose-inhibitor resistant plants [PDF]

, 2019
The rapid appearance of herbicide-resistant weeds combined with a lack of novel herbicides being brought to market reduces crop production, thereby threatening food security worldwide.
D'Haeyer, Sam, De Veylder, Lieven, Decaestecker, Ward, Hu, Zhubing, Höfer, René, Jacobs, Thomas, Karimi, Mansour, Rombaut, Debbie, Vercauteren, Ilse, Xing, Aiming, Zhang, Teng   +10 more
core   +1 more source

Isonitrile Photochemistry: A Functional Group Class Coming in from the Cold

Chemistry – A European Journal, Volume 30, Issue 64, November 15, 2024.
Isonitriles, often neglected for their unpleasant smell, have fascinated many generations of chemists thanks to unique reactivity modes. The present concept article, by retracing the seeds of isonitrile photochemistry, points out the hidden opportunities offered by visible light photo(redox) catalysis to promote key advancements in the field.
Mariateresa Giustiniano
wiley   +1 more source

Designing helical peptide inhibitors of protein–protein interactions [PDF]

, 2018
Short helical peptides combine characteristics of small molecules and large proteins and provide an exciting area of opportunity in protein design. A growing number of studies report novel helical peptide inhibitors of protein-protein interactions.
Keating, Amy E., Rezaei Araghi, Raheleh
core   +1 more source

The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma. [PDF]

, 2014
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously.
Anandan C., Arbes S. J., Asokananthan N., Billson J., Boyd M. J., Brown A., Brown A. D., Chan W. C., Chen J. C., Clive Robinson, Comoy E. E., David R. Garrod, Fattouh R., Gary K. Newton, Gelber L. E., Gough L., Jahnsen F. L., Jie Chen, Jihui Zhang, Jonathan P. Richardson, Kerry Jenkins, King C., Liu H., Marcaccini S., Mark R. Stewart, Meriel R. Major, Milan D. S., Moffatt M. F., Möller G. M., Nicola J. Francis-Newton, Peat J. K., Peat J. K., Pei Lai, Pichavant M., Platts-Mills T. A., Platts-Mills T. A., Platts-Mills T. A. E., Platts-Mills T. A. E., Prefontaine D., Purello-D’Ambrosia F., Rebekah E. Key, Robinson C., Silvestri M., Smith J. M., Sporik R., Squillace S. P., Steven M. Lloyd, Stewart G. A., Stuart Firth-Clark, Takai T., Trevor R. Perrior, Wan H., Ying S., Zhang J., Zhang J., Zhang J., Zhang J.   +56 more
core   +2 more sources

A modular, one-pot, four-component synthesis of polysubstituted 1,3-oxazolidines [PDF]

, 2005
4 pages, 1 figure, 1 table, 1 scheme.-- PMID: 15675866 [PubMed].-- Printed version published Feb 4, 2005.Supporting information available: Spectroscopic and analytical data for compounds 3c-j.-- Available at: http://pubs.acs.org/doi/suppl/10.1021 ...
García-Tellado, Fernando, González-Cruz, David, Marrero-Tellado, José Juan, Santos-Expósito, Alicia, Tejedor, David   +4 more
core   +1 more source

Expanding plant genome editing scope and profiles with CRISPR‐FrCas9 systems targeting palindromic TA sites

Plant Biotechnology Journal, Volume 22, Issue 9, Page 2488-2503, September 2024.
Summary CRISPR‐Cas9 is widely used for genome editing, but its PAM sequence requirements limit its efficiency. In this study, we explore Faecalibaculum rodentium Cas9 (FrCas9) for plant genome editing, especially in rice. FrCas9 recognizes a concise 5′‐NNTA‐3′ PAM, targeting more abundant palindromic TA sites in plant genomes than the 5′‐NGG‐3′ PAM ...
Yao He, Yangshuo Han, Yanqin Ma, Shishi Liu, Tingting Fan, Yanling Liang, Xu Tang, Xuelian Zheng, Yuechao Wu, Tao Zhang, Yiping Qi, Yong Zhang   +11 more
wiley   +1 more source