Results 161 to 170 of about 14,737 (217)

Planar Chirality Directs Enantiospecific Diastereoselectivity in Isocyanide-Based Multicomponent Reactions. [PDF]

open access: yesACS Org Inorg Au
Kapsalis M   +7 more
europepmc   +1 more source

Analysis of real-world clinical outcomes of perioperative chemotherapy compared to preoperative chemoradiotherapy in esophagogastric adenocarcinoma. [PDF]

open access: yesCancer
Oyenuga M   +10 more
europepmc   +1 more source

Dietary management and feeding considerations of pediatric aerodigestive and upper gastrointestinal motility disorders. [PDF]

open access: yesJ Pediatr Gastroenterol Nutr
El-Chammas K   +8 more
europepmc   +1 more source

Cyclic Imines in Ugi and Ugi-Type Reactions

ACS Combinatorial Science, 2020
Ugi four-component reactions (U-4CRs) are widely recognized as being highly efficient for the synthesis of pseudopeptides. However, the products of these reactions are not so interesting as drug candidates because they are not conformationally restricted enough for a potent interaction with biological targets.
Ahmad Shaabani   +2 more
exaly   +3 more sources

Insight into the Mechanisms of the Multicomponent Ugi and Ugi–Smiles Reactions by ESI‐MS(/MS)

open access: yesEuropean Journal of Organic Chemistry, 2014
AbstractThe mechanisms of the Ugi and Ugi–Smiles reactions were investigated by using finely selected reaction conditions that allowed all of the intermediates to be “fish‐out” and characterized by ESI‐MS/MS. New insight into the Ugi and Ugi–Smiles reaction mechanisms is provided without using charge‐tagged reagents.
IACOBUCCI, CLAUDIO   +3 more
openaire   +2 more sources

A Diastereoselective Synthesis of Pseudopeptidic Hydantoins by an Ugi/Cyclization/Ugi Sequence

Tetrahedron, 2012
Abstract A diastereoselective synthesis of helix-forming pseudopeptidic hydantoins by an Ugi 4CC/cyclization/reduction/Ugi 4CC sequence of reactions, giving mainly the l -adduct when benzoic acids were used, is described.
María García-Valverde   +2 more
exaly   +2 more sources

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