Results 71 to 80 of about 38,024 (237)
Measurement-based quantum computation on cluster states [PDF]
We give a detailed account of the one-way quantum computer, a scheme of quantum computation that consists entirely of one-qubit measurements on a particular class of entangled states, the cluster states.
Briegel, HJ, Browne, DE, Raussendorf, R
core +1 more source
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson +6 more
wiley +1 more source
Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system. [PDF]
Precise genetic modifications in model animals are essential for biomedical research. Here, we report a programmable "base editing" system to induce precise base conversion with high efficiency in zebrafish. Using cytidine deaminase fused to Cas9 nickase,
Bai, Haipeng +7 more
core +1 more source
Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu +5 more
wiley +1 more source
Synthesis of Bis-Amides Employing a Plant-Derived Triterpenoid as Component in the Ugi Reaction [PDF]
Fidel Rodríguez-López +2 more
openalex +1 more source
CRISPR Assays for Protein Detection
This review summarizes recent advances in CRISPR–Cas–based strategies for protein detection. Particular focus is placed on recognition element–based approaches, in which antibodies, aptamers, or DNAzymes convert protein binding into CRISPR‐readable nucleic acid signals, and activity‐based strategies that exploit intrinsic protein functions to trigger ...
Luca Capelli +5 more
wiley +1 more source
The rapid urbanization process means that even moderate-sized cities can quickly become part of larger urban agglomerations, creating new urban zones.
Cheng Gong +4 more
doaj +1 more source
We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno +6 more
wiley +1 more source
Optimizing Benefits‐Harms of H. pylori Screen‐and‐Treat Programs Tailored to the Regional Settings
ABSTRACT This article outlines how decision modeling can be used to optimize the cost‐effectiveness of H. pylori screen‐and‐treat programs. Decision models enable the translation of data from pilot studies into locally tailored strategies by adapting test modalities, treatment options, and the need to retest specific to the local setting.
Duco T. Mülder +5 more
wiley +1 more source
The Logic of Consciencism [PDF]
According to Kwame Nkrumah, the conscience of the African society is plagued with three strands of influences which have competing and conflicting ideologies: “African society has one segment which comprises our traditional way of life; it has a second ...
Kwesi, Richmond
core

