Results 61 to 70 of about 14,737 (217)

Molecular Basis for Uracil‐DNA‐Glycosylase to Identify DNA Damage in the Nucleosome

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The DNA base‐excision repair (BER) pathway is initiated by a glycosylase, such as uracil‐DNA‐glycosylase (UDG), which identifies and removes a wrong base incorporated in the DNA sequence. The very early steps in the identification of the DNA damage are crucial to the correct initiation of the repair chain, and become even more complex when ...
Safwen Ghediri, Ralf Blossey, Fabrizio Cleri   +2 more
wiley   +1 more source

Use of a coupled transcriptional system for consistent overexpression and purification of UDG-Ugi complex and Ugi from Escherichia coli

, 1998
We have designed a novel coupled transcriptional construct whereinEscherichia coliuracil DNA glycosylase (UDG) andBacillus subtilisphage PBS-2 encoded uracil DNA glycosylase inhibitor protein (Ugi) genes were cloned in tandem, downstream of an inducible ...
Varshney, Umesh, Boyanapalli, Madanamohan, Roy, Sudipta, Purnapatre, Kedar, Handa, Priya   +4 more
core   +2 more sources

Value of performing routine postoperative liquid contrast swallow studies following robot-assisted Roux-en-Y gastric bypass1

Swiss Medical Weekly, 2012
QUESTIONS UNDER STUDY/PRINCIPLES: In most centers, Upper Gastrointestinal series (UGI) following Roux-en-Y Gastric Bypass (RYGB) is performed to rule out GJ anastomotic leak.
Nicolas C. Buchs, Pascal Bucher, François Pugin, Monika Hagen, Gilles Chassot, Pascale Koutny-Fong, Philippe Morel   +6 more
doaj   +1 more source

Síntesis de un nuevo sistema bis-tetrazol-benzofurano mediante los procesos: reducción/RMC Ugi-azida/oxidación/RMC Ugi-azida

, 2023
Facultad de Químico Farmacobiología. Licenciatura como Químico FarmacobiólogoIn this thesis work, we describe a novel synthesis strategy to obtain a new hybrid system of the bis-tetrazole 1,5-disubstituted-benzofuran type under an operationally simple ...
Mitzi Nohemi Piña Gordillo
core  

From Plot to Block: Participatory Land Use for Climate‐Resilient Detached Housing in Finland

Sustainable Development, EarlyView.
ABSTRACT This study investigates how urban planning in Finland is adapting to climate change, focusing on the practical challenges planners face in single‐family housing areas. It draws on participatory workshops with municipal planners in Pori and Joensuu, where three planning tools—green factor metrics, impermeable surface limits, and the 3–30‐300 ...
Hossam Hewidy
wiley   +1 more source

Structural and biophysical analysis of interactions between cod and human uracil-DNA N-glycosylase (UNG) and UNG inhibitor (Ugi) [PDF]

, 2014
Uracil-DNA N-glycosylase from Atlantic cod (cUNG) shows cold-adapted features such as high catalytic efficiency, a low temperature optimum for activity and reduced thermal stability compared with its mesophilic homologue human UNG (hUNG).
Willassen, Nils Peder, Johnson, Kenneth, Moe, Elin, Niiranen, Laila, Leiros, Hanna-Kirsti S., Smalås, Arne O., Assefa, Netsanet Gizaw   +6 more
core   +1 more source

Dynamical refinement against 3D‐ED data in Olex2–AutoChem using the N‐Beam approach

Journal of Applied Crystallography, EarlyView.
Dynamical diffraction effects in electron diffraction can now be modelled directly within Olex2–AutoChem using data processed with CrysAlisPro, enabled by a new N‐Beam refinement method based on the Bloch‐wave formalism. This workflow allows dynamical refinement of integrated rotation electron diffraction intensities, improving structural models and ...
Oleg Dolomanov, Grzegorz Próchniak, Przemysław Steć, Mathias Meyer, Horst Puschmann   +4 more
wiley   +1 more source

Impact of Upper Gastrointestinal Involvement on Clinical Outcomes in Paediatric Inflammatory Bowel Disease

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to assess the clinical implications of upper gastrointestinal (UGI) involvement in paediatric inflammatory bowel disease (IBD). Methods This retrospective cohort study included children diagnosed with IBD between 2010 and 2023, who underwent a UGI endoscopic evaluation at diagnosis and were followed for at least ...
Ofek Aloni, Adi Anafy, Hadar Moran‐Lev, Achiya Amir, Alma Ziv, Reut Doyev, Tut Galai, Shlomi Cohen, Anat Yerushalmy‐Feler   +8 more
wiley   +1 more source

Using Triazolobenzodiazepine as the Cyclic Imine in Various Types of Joullié–Ugi Reactions

The triazolobenzodiazepine as a cyclic imine was employed in a variety of Joullié–Ugi reactions, and three new families of unique triazolobenzodiazepine connected to carboxamide and tetrazole products were synthesized via a three-component reaction of ...
Maryam Ghasemi (12366706), Ahmad Shaabani (1821601), Mohammad Taghi Nazeri (16966224), Masoomeh Ahmadi (16966227), Behrouz Notash (691974)   +4 more
core   +2 more sources

The Elements of Chiral Brønsted Acids for Stereoselective Transformations

Asian Journal of Organic Chemistry, Volume 15, Issue 11, November 2026.
This review focuses on chiral Brønsted acids (CBAs), examining how each structural component influences the stereochemical outcome. For each element—scaffold, acidic site, substituents—we identify advantages and disadvantages relevant to the catalyst design and selection.
Diego A. Cruz‐Aguilar, Margarita Cantú‐Reyes, David A. Contreras‐Cruz, Eddy I. Jiménez   +3 more
wiley   +1 more source