Results 41 to 50 of about 14,737 (217)

Application of heterocyclic aldehydes as components in Ugi–Smiles couplings

Beilstein Journal of Organic Chemistry, 2016
Efficient one-pot Ugi–Smiles couplings are reported for the use of furyl-substituted aldehyde components. In the presence of these heterocyclic aldehydes, reactions tolerated variations in amine components and led to either isolated N-arylamide Ugi ...
Katelynn M. Mason, Michael S. Meyers, Abbie M. Fox, Sarah B. Luesse   +3 more
doaj   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

UGI surgery (DRAFT)

, 2018
The upper gastrointestinal (UGI) tract comprises of the oesophagus, stomach, and duodenum. Although some emergency management of UGI pathology may fall to the remit of the gastroenterologists, this chapter focuses specifically on surgical management of ...
Roger Ackroyd, Corinne Owers
core   +1 more source

Impact of urban green infrastructure on ecosystem services: A systematic review

Ecological Indicators
Urban green infrastructure (UGI) plays a key role in providing various ecosystem services (ES), which contribute to urban residents’ well-being and sustainable city management.
Yunong Yao, Hua Zheng, Zhiyun Ouyang, Cheng Gong, Jian Zhang, Lingxiao Ying, Zhi Wen   +6 more
doaj   +1 more source

The effectiveness of urban green infrastructure in reducing surface urban heat island

Ain Shams Engineering Journal, 2022
In the era of the devastating impacts of climate change, many cities around the world make strenuous efforts to find suitable and sustainable adaptation strategies to address the climatic dangers.
Maryam F. Abdulateef, Hoda A. S. Al-Alwan   +1 more
doaj   +1 more source

Direct synthesis of the arylboronic acid analogues of phenylglycine via microwave-assisted four-component Ugi reaction

, 2014
A four-component Ugi reaction (Ugi-4CR) utilizing formylphenyl boronic acids under mild condition was developed for the synthesis of arylboronic acid analogs.
Lian, Ru-Ching; Lin, Meng-Hsuan; Liao, Pin-Hsuan; Fu, Jia-Jie; Wu, Meng-Ju; Wu, Yang-Chang; Chang, Fang-Rong; Wu, Chin-Chung; Pan, Po-Shen, Pan, Po-Shen   +1 more
core   +1 more source

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

Biotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal, Catarina Domingos, André Nascimento, José Mendes, Afonso B. Ruiz, Ana Margarida Gonçalves Carvalho Dias, Luisa M. Ferreira, Cristina Peixoto, Ana Cecília Afonso Roque   +8 more
wiley   +1 more source

Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry

Bulletin of the Korean Chemical Society, EarlyView.
Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah, Amirreza Mottafegh, Su‐Hyun Yoo, Jongwoon Kim, Minseon Byeon, Juhwan Noh, Yea‐Lee Lee, Jin Suk Myung, Gwang‐Noh Ahn   +8 more
wiley   +1 more source

Total synthesis of natural products with Ugi reactions [PDF]

, 2015
Die Ugi-4-Komponentenreaktion stellt heutzutage eine der effizientesten Verfahren zur Gewinnung von komplexen und vielfältigen chemischen Strukturen dar. Unter Beachtung der hohen chemischen Effizienz und geringen Anzahl an Edukten, weist sie ein enormes
Neves Filho, Ricardo Antonio Wanderley
core   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

Bulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon, Hyemin Yoon, Kang Ju Lee, Hyun Jin Kim   +3 more
wiley   +1 more source