Results 41 to 50 of about 7,285 (139)

Ugi Four-Component Reactions Using Alternative Reactants

Molecules, 2023
The Ugi four-component reaction (Ugi-4CR) undoubtedly is the most prominent multicomponent reaction (MCRs) that has sparked organic chemists’ interest in the field.
Seyyed Emad Hooshmand, Wei Zhang
doaj   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

Biotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal, Catarina Domingos, André Nascimento, José Mendes, Afonso B. Ruiz, Ana Margarida Gonçalves Carvalho Dias, Luisa M. Ferreira, Cristina Peixoto, Ana Cecília Afonso Roque   +8 more
wiley   +1 more source

Design, Synthesis, and Photophysical Studies of Functionalized Polyaromatic Isonitriles as Visible Light Photoredox Catalysts

European Journal of Organic Chemistry, EarlyView.
A new series of structurally rich polyaromatic isonitriles is presented as photoredox catalysts. Their photophysical properties are investigated by UV–Vis absorption and fluorescence measurements, combined with experimental and theoretical studies to evaluate both ground‐ and excited‐state redox properties.
Cristina Martini, Camilla Russo, Jussara Amato, Carmine Volpe, Francesca Brunelli, Laurence Grimaud, Maxime R. Vitale, Greta Donati, Andrea Basso, Mariateresa Giustiniano   +9 more
wiley   +1 more source

Synthesis of Oxazolyl‐Piperidines Bearing a Quaternary Stereocenter Through a Multicomponent Reaction Involving α‐Isocyanoacetates and Piperidones

European Journal of Organic Chemistry, EarlyView.
Straightforward access to oxazole‐containing piperidines through a multicomponent reaction from α‐isocyanoacetates is described. By expanding the reactivity of these a‐isocyanoacetates from aldehydes to ketones, this process efficiently delivers oxazolyl‐piperidines bearing a quaternary stereocenter as valuable scaffolds relevant to drug discovery. The
Roshan Chandrakant Kajare, Gilles Argouarch, Nicolas Gouault, Claudia Lalli   +3 more
wiley   +1 more source

Urban green infrastructure: bridging biodiversity conservation and sustainable urban development through adaptive management approach

Frontiers in Ecology and Evolution
Urban green infrastructure (UGI) is pivotal in reconciling biodiversity conservation with sustainable urban development through adaptive management approaches.
Dong Wang, Pei-Yuan Xu, Bo-Wen An, Qiu-Ping Guo   +3 more
doaj   +1 more source

Associated factors of atrophic gastritis diagnosed by double-contrast upper gastrointestinal barium X-ray radiography: a cross-sectional study analyzing 6,901 healthy subjects in Japan. [PDF]

PLoS ONE, 2014
Double-contrast upper gastrointestinal barium X-ray radiography (UGI-XR) is one of the most widely conducted gastric cancer screening methods. It has been executed to find gastric cancer, but has not been usually executed to detect premalignant atrophic ...
Nobutake Yamamichi, Chigaya Hirano, Takeshi Shimamoto, Chihiro Minatsuki, Yu Takahashi, Chiemi Nakayama, Rie Matsuda, Mitsuhiro Fujishiro, Maki Konno-Shimizu, Jun Kato, Shinya Kodashima, Satoshi Ono, Keiko Niimi, Satoshi Mochizuki, Yosuke Tsuji, Yoshiki Sakaguchi, Itsuko Asada-Hirayama, Chihiro Takeuchi, Seiichi Yakabi, Hikaru Kakimoto, Ryoichi Wada, Toru Mitsushima, Masao Ichinose, Kazuhiko Koike   +23 more
doaj   +1 more source

Helicobacter pylori infection a risk for upper gastrointestinal diseases among patients in North Central Nigeria

Nigerian Journal of Medicine, 2021
Background: Since the discovery of the Upper Gastrointestinal (UGI) fiber optic endoscope machine in 1868 and following the discovery of Helicobacter pylori (H- Pylori) infection and its association with most gastroduodenal diseases in 1983 by Robin ...
Kefas P Zawaya, Jacob A Dunga, Yakubu Adamu, Sule J Bathnna, Haruna U Liman, Jafiada J Musa, Sulaiman Y Yusuf, Innocent Vakkai, Ruth Adabe, E N Okeke, E I Agaba   +10 more
doaj   +1 more source

Predictive Value of Nutrition Indices in Advanced Hepatocellular Carcinoma Patients Treated With Lenvatinib

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prognostic nutritional index (PNI) and geriatric nutritional risk index (GNRI) are simple markers that reflect immune and nutritional status. This retrospective study evaluated their prognostic significance in 276 patients with advanced hepatocellular carcinoma (HCC) who received first‐line lenvatinib. PNI and GNRI were calculated based on
Cheng‐Wei Kuo, Wei‐Chen Tai, Yen‐Hao Chen, Ming‐Chao Tsai, Jing‐Houng Wang, Sheng‐Nan Lu, Tsung‐Hui Hu, Chao‐Hung Hung, Chien‐Hung Chen, Yuan‐Hung Kuo   +9 more
wiley   +1 more source

Paradigm shift in Etiology of Upper Gastrointestinal Bleed in Emergency Department

Journal of Renal and Hepatic Disorders, 2021
Background and Aims: Acute upper gastrointestinal (UGI) bleed is an emergency requiring immediate intervention. Recent data have shown peptic ulcer disease (PUD) to be commonest cause of UGI bleed. We aimed to evaluate all patients of UGI bleed reporting
Tarana Gupta, Sandeep Goyal
doaj   +1 more source