Results 31 to 40 of about 7,468 (177)
Терапевтический архив, 2020 Introduction.Upper gastrointestinal (UGI) bleeding is a common complication of antiplatelet therapy. Data from real clinical practice that characterize the range of risk factors for UGI bleeding, prophylactic proton pump inhibitors (PPIs) therapy ...
O. O. Shakhmatova +6 more
doaj +1 more source
Diverse Isoquinoline Scaffolds by Ugi/Pomeranz–Fritsch and Ugi/Schlittler–Müller Reactions [PDF]
Organic Letters, 2019 The Pomeranz-Fritsch reaction and its Schlittler-Müller modification were successfully applied in the Ugi postcyclization strategy by using orthogonally protected aminoacetaldehyde diethyl acetal and complementary electron rich building blocks. Several scaffolds, including isoquinolines, carboline, alkaloid-like tetrazole-fused tetracyclic compounds ...
Yuanze Wang +4 more
openaire +3 more sources
Ecological IndicatorsUrban green infrastructure (UGI) that provides diverse ecosystem services are crucial components of a city. Achieving appropriate density and equitable distribution of UGI is highly significant for urban planning to ensure sustainable and high-quality ...
Wei Hou, Xinpeng Li
doaj +1 more source
Applications of the Ugi reaction with ketones [PDF]
Tetrahedron Letters, 2008 A convenient synthesis of highly functionalized, α,α-disubstituted amino acid amide derivatives has been accomplished by using cyclic and acyclic ketones as the carbonyl inputs in the Ugi multicomponent reaction. An application of this extension of the Ugi reaction to the synthesis of α,α-divinyl amino acids that may be cyclized via ring-closing ...
Suvi T M, Simila, Stephen F, Martin
openaire +2 more sources
, 2014 A four-component Ugi reaction (Ugi-4CR) utilizing formylphenyl boronic acids under mild condition was developed for the synthesis of arylboronic acid analogs.
Lian, Ru-Ching; Lin, Meng-Hsuan; Liao, Pin-Hsuan; Fu, Jia-Jie; Wu, Meng-Ju; Wu, Yang-Chang; Chang, Fang-Rong; Wu, Chin-Chung; Pan, Po-Shen +1 more
core +1 more source
Hydrazine in the Ugi Tetrazole Reaction [PDF]
Synthesis, 2016 We describe the hitherto unknown use of N-Boc-protected hydrazine in the Ugi tetrazole reaction to access a library of highly substituted 5-(hydrazinomethyl)-1-methyl-1H-tetrazoles. The reaction is very versatile and good to high yielding. A one-pot, two-step procedure is given.
Patil +5 more
openaire +3 more sources
Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo
Advanced Science, EarlyView.As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao +12 more
wiley +1 more source
Nilai-Nilai Pendidikan dalam Élong Ugi Assimélléréng [PDF]
, 2020 Jenis penelitian adalah penelitian kualitatif. Data dalam peneltian ini adalah data tertulis berupa kalimat yang mengandung dengan nilai-nilai pendidikan moral dan pendidikan sosial yang terdapat di dalam élong.
Yusryana, Yusryana +2 more
core
Engineered Transformer Base Editor with Enhanced Editing Efficiency
Advanced Science, EarlyView.A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
Endoscopic features of cytomegalovirus disease of the upper gastrointestinal tract between transplant and non-transplant patients [PDF]
The Korean Journal of Internal MedicineBackground/Aims Cytomegalovirus (CMV) disease in the upper gastrointestinal (UGI) tract frequently occurs in immunocompromised patients. However, data regarding UGI CMV disease in non-transplant patients compared with those in transplant recipients are ...
Yuri Kim +10 more
doaj +1 more source