Results 1 to 10 of about 51,777 (142)
UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosis [PDF]
Scientific ReportsThe diagnosis of Lyme neuroborreliosis (LNB) requires the demonstration of intrathecal synthesis of Borrelia antibodies in a patient’s cerebrospinal fluid (CSF), which involves the invasive procedure of a lumbar puncture.
Ilari Kuukkanen +8 more
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Development and Validation of a UHPLC-MS/MS Method for Ciprofol Detection in Plasma: Application in Clinical Pharmacokinetic Studies [PDF]
Drug Design, Development and TherapyJiaxi Zhu,1,2,* Ying Cao,2,* Xingan Zhang,2 Bo Xu2 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, People’s Republic of China; 2Department of Anesthesiology, General Hospital of Southern ...
Zhu J, Cao Y, Zhang X, Xu B
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Muscle Biopsy Sample Preparation and Proteomics Analysis Based on UHPLC-MS/MS [PDF]
Bio-ProtocolProteomics analysis is crucial for understanding the molecular mechanisms underlying muscle adaptations to different types of exercise, such as concentric and eccentric training.
Jiawei Du +3 more
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Development of a novel UHPLC-MS/MS method for quantitative analysis of pirtobrutinib in rat plasma: application to pharmacokinetic study [PDF]
BMC ChemistryBruton’s tyrosine kinase (BTK) inhibitors play a critical role in the treatment of mantle cell lymphoma (MCL). pirtobrutinib, a new, highly selective, non-covalent BTK inhibitor, was approved by the FDA for the treatment of MCL, chronic lymphocytic ...
Meijuan Zhang +5 more
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Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS
Frontiers in Plant Science, 2023 Glucosinolates (GSLs) and their degradation products in radish confer plant defense, promote human health, and generate pungent flavor. However, the intact GSLs in radish have not been investigated comprehensively yet.
Chenghuan Yan +14 more
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Molecules, 2022 Plantago asiatica L. (PAL) as a medicinal and edible plant is rich in chemical compounds, which makes the systematic and comprehensive characterization of its components challenging.
Hongxue Gao +5 more
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Grape Lipidomics: An Extensive Profiling thorough UHPLC-MS/MS Method
Metabolites, 2021 Lipids play many essential roles in living organisms, which accounts for the great diversity of these amphiphilic molecules within the individual lipid classes, while their composition depends on intrinsic and extrinsic factors.
Domenico Masuero +7 more
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Marine Drugs, 2021 Butyrolactone I (BTL-I) is a butanolide isolated from the deep-sea-derived fungus, Aspergillus sp. It provides a potential new target for the prevention and treatment of food allergies.
Liang Wu +3 more
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Frontiers in Molecular Biosciences, 2021 Metabolomics has emerged as a powerful discipline to study complex biological systems from a small molecule perspective. The success of metabolomics hinges upon reliable annotations of spectral features obtained from MS and/or NMR. In spite of tremendous
Rajarshi Ghosh +11 more
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Molecules, 2021 Two new ultra-high performance liquid chromatography (UHPLC) methods for analyzing 21 selected antivirals and their metabolites were optimized, including sample preparation step, LC separation conditions, and tandem mass spectrometry detection.
Luboš Fical +8 more
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