Results 11 to 20 of about 51,926 (282)
Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS
Journal of Pharmaceutical Analysis, 2019 One of the most important tools used to evaluate kidney function in the context of chronic kidney disease or other renal function related pathologies is the exploration of glomerular filtration rate (GFR).
Valentin Ion +6 more
doaj +4 more sources
Quantitative Lipidomic Analysis of Osteosarcoma Cell-Derived Products by UHPLC-MS/MS [PDF]
Biomolecules, 2020 Changes in lipid metabolism are involved in several pathological conditions, such as cancer. Among lipids, eicosanoids are potent inflammatory mediators, synthesized from polyunsaturated fatty acids (PUFAs), which coexist with other lipid-derived ones ...
Sara Casati +10 more
doaj +3 more sources
Determination of lesinurad in rat plasma by a UHPLC–MS/MS assay [PDF]
Chemistry Central Journal, 2017 Lesinurad is an oral inhibitor of urate-anion exchanger transporter 1 and has been approved by the US Food and Drug Administration for combination therapy with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with refractory ...
Xiao-Yang Zhou +6 more
doaj +3 more sources
UHPLC-MS/MS-based untargeted lipidomics analysis of septic patients
Clinica Chimica Acta, 2023 Lipids take part in many pathophysiological processes of sepsis, thus, the variation of lipid composition may have clue on the severity and pathogen to sepsis. The objective of our study is to expand the profile of lipid compositions and screen potential biomarkers in intensive care unit (ICU) patients with sepsis.Patients admitted to the ICU clearly ...
Jifang, Liang +8 more
openaire +2 more sources
Characterization of URB Series Synthetic Cannabinoids by HRMS and UHPLC–MS/MS
Pharmaceuticals, 2023 A large number of synthetic cannabinoids are included in new psychoactive substances (NPS) and constitute an open research area in analytical pharmaceutical and toxicology when methods are needed to unambiguously identify these substances and their ...
Marco Agostini +4 more
doaj +1 more source
INTER-LABORATORY REPRODUCIBILITY OF BIOANALYTICAL UHPLC-MS/MS METHOD
International Journal "Advanced Quality", 2017 Method validation is a continuous process, as a part of a perpetual analytical method development and improvement. Requirements for full validation are defined by various guidelines. Nevertheless, partial validation and method transfer are not so clearly described and well defined.The aim of this study was to examine method transferability through full
Biljana Tubić +2 more
openalex +2 more sources
Future Journal of Pharmaceutical Sciences, 2019 Background UHPLC-MS/MS is connected in various research facilities for the qualitative and quantitative investigation of a pharmaceutical substance, pharmaceutical items, and biological specimen.
Ravsaheb H. Rathod +3 more
doaj +1 more source
Chinese Medicine, 2022 Background Leonuri Herba (Yimucao) is a very common Chinese herbs for treating menstrual and maternal diseases for thousands of years in China. However, the herb collected in different origins was easily found in the markets which induce the unstable ...
Kelly Yinching Lam +5 more
doaj +1 more source
Determination of Paraquat in Arabidopsis Tissues and Protoplasts by UHPLC-MS/MS
Bio-Protocol, 2023 Paraquat is a cost-effective herbicide, widely used in many countries, that can induce severe oxidative stress in photosynthetic tissues. Studying plant herbicide resistance or antioxidant stress mechanisms requires determining the cellular paraquat ...
Mingming Zhao +5 more
doaj +1 more source
Molecules, 2013 Two bisbenzylisoquinoline alkaloids, two morphine alkaloids, one aporphine alkaloid, syringaresinol and aristolochic acid І were selected as marker compounds and simultaneously analyzed using an ultra-high pressure liquid chromatography-diode array ...
Kang Ro Lee +3 more
doaj +1 more source