Results 101 to 110 of about 17,886 (241)
Interactions between mycotoxins and the rumen, their possible toxicological effects on the gastrointestinal tract and their intestinal absorption in dairy cattle : an in vitro approach [PDF]
, 2016 C
Croubels, Siska +6 more
core +1 more source
A method validation for simultaneous determination of phthalates and bisphenol A released from plastic water containers [PDF]
, 2019 Phthalates (or phthalate esters, PAEs) and bisphenol A (BPA) are widely used in various industries, particularly in the fields of cosmetics and packaging, and they increase the malleability and workability of materials.
Avino, P. +4 more
core +1 more source
Advanced Science, EarlyView.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS
Journal of Pharmaceutical Analysis, 2019 One of the most important tools used to evaluate kidney function in the context of chronic kidney disease or other renal function related pathologies is the exploration of glomerular filtration rate (GFR).
Valentin Ion +6 more
doaj +1 more source
Analytical Profiling of Airplane Wastewater - a New Matrix for Mapping Worldwide Patterns of Drug Use and Abuse [PDF]
, 2017 There is limited knowledge on the global prescription and consumption patterns of therapeutic (TD) and illicit drugs (ID). Pooled urine analysis and wastewater-based epidemiology (WBE) has been used for local-based drug screening.
Aarestrup, Frank Møller +5 more
core +2 more sources
Advanced Science, EarlyView.PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Angewandte Chemie, EarlyView.The thiocarbenium ion rearrangement of 3‐dihydrodisorhabdin B greatly increases the recovery of aleutianamine from Latrunculia spp., a pyrroloiminoquinone natural product with potent activity against drug‐resistant cancers, collected from the deep‐ocean along the Aleutian Islands.
Cody F. Dickinson +13 more
wiley +2 more sources
Advanced Science, EarlyView.Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng +7 more
wiley +1 more source
INTER-LABORATORY REPRODUCIBILITY OF BIOANALYTICAL UHPLC-MS/MS METHOD
International Journal "Advanced Quality", 2017 Method validation is a continuous process, as a part of a perpetual analytical method development and improvement. Requirements for full validation are defined by various guidelines. Nevertheless, partial validation and method transfer are not so clearly described and well defined.The aim of this study was to examine method transferability through full
Bojan D. Marković +2 more
openaire +1 more source
New Method for Simultaneous Determination of Microcystins and Cylindrospermopsin in Vegetable Matrices by SPE-UPLC-MS/MS [PDF]
, 2018 Cyanotoxins are a large group of noxious metabolites with different chemical structure and mechanisms of action, with a worldwide distribution, producing effects in animals, humans, and crop plants.
Cameán Fernández, Ana María +7 more
core +1 more source