Results 241 to 250 of about 2,976,642 (307)

UHPLC-MS-Based Analysis of Fluvoxamine in Rabbit Aqueous Humour and Serum: Method Development and Validation. [PDF]

Pharmaceuticals (Basel)
Guba A, Takácsi-Nagy A, Das S, Szokol B, Timea M, Vajna M, Kalló G, Fekete A, Hodrea J, Csősz É.   +9 more
europepmc   +1 more source

Seasonal and Regional Dietary Heterogeneity Is Associated With Gut Microbiota Differentiation in Przewalski's Gazelle (Procapra przewalskii)

Integrative Zoology, EarlyView.
Seasonal and regional dietary variation in Przewalski's gazelle was linked to coordinated changes in gut microbiota, functional pathways, and fecal metabolites. Winter diets featured Poaceae, Cyperaceae, and Iridaceae, whereas summer diets shifted toward forb families.
Jingjie Zhang, Chengbo Liang, Feng Jiang, Xin Zhao, Tongzuo Zhang   +4 more
wiley   +1 more source

Development and Validation of a Cannabinoid Quantification Method in Oil and Marijuana by UHPLC-MS. [PDF]

ACS Omega
de Almeida JVM, Conceição NS, Pereira AR, Lyrio MVV, Ortiz RS, Dos Santos NA, Romão W.   +6 more
europepmc   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

Allergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan, Xufeng Qu, Carmen Camarena, Araba Abaidoo‐Myles, Parth Naik, Jeremy Allegood, Ankit Kumar, Mihir Pokhriyal, Joseph C. Lownik, Matthew P. Zellner, Grayson W. Way, Jinze Liu, Lauren Ashley Cowart, Stephanie C. Eisenbarth, Joseph W. Landry, Daniel H. Conrad, Rebecca K. Martin   +16 more
wiley   +1 more source

GC-Ms, UHPLC-MS/MSⁿ Phytoconstituents Characterization and Physio-pharmacological Investigation of Silene colorata subsp. amphorina (Pomel) Batt. From Northeastern Algeria. [PDF]

Chem Biodivers
Bensaad MS, Allaoua Z, Kahoul MA, Pinto DCGA, Bensouici C, Akkal S.   +5 more
europepmc   +1 more source

Plasma and colostrum concentrations of fentanyl in clinical practice: Intravenous versus epidural administration for labor analgesia

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Midwife‐administered intravenous fentanyl may be considered a feasible option for labor analgesia. Abstract Introduction Pain relief during labor is essential. Systemic opioids for labor analgesia have been used for decades as a less invasive alternative to epidural analgesia (EA).
Benedicte Sandhaug Nygaard, Ragnhild Bergene Skråstad, Olav Spigset, Tonje Gottenberg Skaalvik, Are Hugo Pripp, Janne Rossen   +5 more
wiley   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier, Sandra Szu‐Wei Hwang, Anthony F. Rullo   +2 more
wiley   +1 more source

Cylindrospermopsin toxicokinetics: in silico ADMET modeling, rat and human liver microsome metabolism, and UHPLC-MS/MS metabolite characterization. [PDF]

Arch Toxicol
Cascajosa-Lira A, Guzmán-Guillén R, Cameán AM, Jos A, Prieto AI.   +4 more
europepmc   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

ZrO₂-Assisted QuEChERS-UHPLC-MS/MS for Simultaneous Determination of Four Aflatoxins in Cereals and Soybean Matrices. [PDF]

Toxins (Basel)
Liu S, Zheng X, Zhang S, Guo N, Zhang H, Shi J.   +5 more
europepmc   +1 more source