Results 111 to 120 of about 67,993 (297)
Muscle Biopsy Sample Preparation and Proteomics Analysis Based on UHPLC-MS/MS
Bio-ProtocolProteomics analysis is crucial for understanding the molecular mechanisms underlying muscle adaptations to different types of exercise, such as concentric and eccentric training.
Jiawei Du +3 more
doaj +1 more source
A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing
Advanced Science, EarlyView.A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu +12 more
wiley +1 more source
Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis
Advanced Science, EarlyView.Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing +9 more
wiley +1 more source
Phenolic compounds in apple juices - Method of quantification by UHPLC-UV and UHPLC-MS/MS [PDF]
, 2012 An UPHLC-UV/MS/MS method was developed for separation and quantification of major polyphenolic compounds present in apple juice. The main classes of polyphenols studied here are monomeric or polymeric flavan-3-ols, phenolic acids, flavonols and ...
Freuze, Ingrid +12 more
core
Advanced Science, EarlyView.Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An +11 more
wiley +1 more source
BMC Research Notes, 2019 Objective Short-chain triacylglycerols (TAGs) in lipid extracts of biological samples are not sufficiently resolved using conventional reversed-phase separation on two C18 columns in series, or using a two-dimensional chromatographic separation with a ...
William Craig Byrdwell
doaj +1 more source
Rapid analytical method for lentil soyasaponins quantification by using UHPLC-MS/MS. [PDF]
, 2013 Lentils (Lens Culinaris Medik) belonging to the family of leguminosae, contain a rich variety of nutraceutical compounds, among them saponins, mainly soyasaponins I and βg, which have multiple health-promoting properties such as lowering plasma ...
Paolo Conti +8 more
core
Advanced Science, EarlyView.Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li +8 more
wiley +1 more source
Chemometric Optimization of UHPLC Separation of Multiclass Pesticides of Environmental Interest
Applied SciencesPesticides constitute a critical class of anthropogenic contaminants whose pervasive occurrence in surface waters, groundwater, and drinking water distribution systems poses substantial ecological and public health risks.
Fabrizio Ruggieri +5 more
doaj +1 more source
NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis
Advanced Science, EarlyView.In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu +11 more
wiley +1 more source