Results 101 to 110 of about 8,179,520 (254)

Categorical Features from Question Answers in UK Biobank data fields.

, 2022
Categorical Features from Question Answers in UK Biobank data fields.
Ruoqing Zhu (724776), Bruce Schatz (13988704), Anita Ung (13988701), Haowen Zhou (368727)   +3 more
core   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Association between physical activity and all-cause mortality in rheumatoid arthritis: evidence from NHANES and UK Biobank cohort studies

Arthritis Research & Therapy
Importance Rheumatoid arthritis (RA), a chronic autoimmune disease linked to higher mortality, benefits from physical activity (PA), which has been shown to reduce disease activity and improve physical function.
Haodong Zheng, Yunfeng Dai, Jiaye Fang, Shaowei Lin, Fei Gao, Junping Wen, Zhihan Chen   +6 more
doaj   +1 more source

Observed and expected LTC counts in UK Biobank.

, 2022
The grey bars show the observed LTC counts in UK Biobank. The blue line shows the expected LTC counts in UK Biobank based on the age and sex adjusted regression models fitted in SAIL. The red line shows the expected LTC counts in UK Biobank based on age,
David A. McAllister (9548352), Peter Hanlon (3498404), Bhautesh D. Jani (9262384), Barbara Nicholl (6574187), Jim Lewsey (9548349), Frances S. Mair (7784447)   +5 more
core   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

The Potential of Microbiota-Modulating Dietary Strategies in Gallstone Prevention: Evidence from 2 Large Population- Based Cohorts

The Turkish Journal of Gastroenterology
Background/Aims: Gut–microbiota dysbiosis has been implicated in gallstone formation through alterations in bile acid and cholesterol metabolism, but whether adherence to a microbiota-supportive diet is associated with gallstone disease at the population
Hongyan He, Luohong Li, Xiaoli Yang
doaj   +1 more source

Summary statistics of the UK Biobank participants in our sample.

, 2021
Summary statistics of the UK Biobank participants in our sample.
Tom R. Gaunt (7747922), Louise A. C. Millard (6288416), David Carslake (313427), Deborah A. Lawlor (4694008), Kate Tilling (213507)   +4 more
core   +1 more source

AI Powered Biobanks From Static Archives to Dynamic Discovery Engines

Advanced Intelligent Discovery, EarlyView.
Large language models (LLMs) provide a potential framework for transforming biobanks from static data repositories into intelligent discovery engines. By enabling unified representation and analysis of multimodal biomedical data, LLM‐based systems facilitate dynamic risk prediction, biomarker identification, and mechanistic interpretation, thereby ...
Wenzhen Yin, Yutian Feng, Wenrui Ma, Yuxin Su, Li Min, Juan Liu   +5 more
wiley   +1 more source

Combined social determinants of health contributed to adverse health outcomes among depression: evidence from two national cohorts

Epidemiology and Psychiatric Sciences
Aims Social determinants of health (SDHs) exert a significant influence on various health outcomes and disparities. This study aimed to explore the associations between combined SDHs and mortality, as well as adverse health outcomes among adults with ...
Xin Qi, Li Liu, Jin Yang, Chuyu Pan, Jingcan Hao, Wenming Wei, Shiqiang Cheng, Yifan Gou, Boyue Zhao, Yan Wen, Bolun Cheng, Feng Zhang   +11 more
doaj   +1 more source

Invitation and recruitment to UK Biobank.

, 2013
Invitation and recruitment to UK Biobank.
Nick Craddock (170215), Jill P. Pell (238644), Zia Ul-Haq (489584), Daniel J. Smith (388567), Jonathan Evans (489585), Barbara I. Nicholl (489582), Ian Deary (489588), Daniel Mackay (489587), Beverly Roberts (489586), Matthew Hotopf (51508), Jason M. R. Gill (206415), Breda Cullen (489583), Daniel Martin (101430), John Gallacher (196569)   +13 more
core   +1 more source