Results 81 to 90 of about 121,766 (195)

Quantile Regression for biomarkers in the UK Biobank

, 2023
AbstractGenome-wide association studies (GWAS) for biomarkers important for clinical phenotypes can lead to clinically relevant discoveries. GWAS for quantitative traits are based on simplified regression models modeling the conditional mean of a phenotype as a linear function of genotype.
Wang, Chen, Wang, Tianying, Wei, Ying, Aschard, Hugues, Ionita-Laza, Iuliana   +4 more
openaire   +2 more sources

Anxiety and Depression in People with Eczema or Psoriasis: A Comparison of Associations in UK Biobank and Linked Primary Care Data

Clinical Epidemiology, 2023
Julian Matthewman,1 Kathryn E Mansfield,1 Joseph F Hayes,2 Elizabeth I Adesanya,1 Catherine H Smith,3 Amanda Roberts,1 Sinéad M Langan,1 Alasdair D Henderson1 1Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical ...
Matthewman J, Mansfield KE, Hayes JF, Adesanya EI, Smith CH, Roberts A, Langan SM, Henderson AD   +7 more
doaj  

Epidemiology of Cholesteatoma in the UK Biobank

Clinical Otolaryngology
ABSTRACT Objectives To identify factors associated with cholesteatoma in a large UK cohort. Although some risk factors are frequently reported (male sex, history of chronic otitis media), other associations require further evidence (deprivation, smoking).
Emma Wilson, Barbara Anne Jennings, Mizanur Khondoker, Carl M. Philpott, Peter Prinsley, Daniel S. Brewer   +5 more
openaire   +4 more sources

Age and cognitive decline in the UK Biobank

PLOS ONE, 2019
Age-related cognitive decline is a well-known phenomenon after age 65 but little is known about earlier changes and prior studies are based on relatively small samples. We investigated the impact of age on cognitive decline in the largest population sample to date including young to old adults.Between 100,352 and 468,534 participants aged 38-73 years ...
Marilyn C. Cornelis, Yamin Wang, Thomas Holland, Puja Agarwal, Sandra Weintraub, Martha Clare Morris   +5 more
openaire   +4 more sources

Mental Health in UK Biobank Revised [PDF]

, 2019
Background\ud UK Biobank is a well-characterised cohort of over 500 000 participants including genetics, environmental data and imaging. An online mental health questionnaire was designed for UK Biobank participants to expand its potential.\ud \ud Aims\ud Describe the development, implementation and results of this questionnaire.\ud \ud Method\ud An ...
Davis, Katrina A S, Coleman, Jonathan R.I., Adams, Mark, Allen, Naomi, Breen, Gerome, Cullen, Breda, Dickens, Chris M, Fox, Elaine, Graham, Nicholas, Holliday, Joanne, Howard, Louise M, John, Ann, Lee, William, McCabe, Rose, McIntosh, Andrew M, Pearsall, Robert, Smith, Daniel J, Sudlow, Cathie, Ward, Joey, Zammit, Stan, Hotopf, Matthew   +20 more
openaire   +2 more sources

Increased risk of hospitalization for various disorders after COVID-19 infection: A Cohort study of the UK biobank spanning over a hundred disease categories

Journal of Microbiology, Immunology and Infection
Background: COVID-19 is one of the most pressing public health issues worldwide. The sequelae of COVID-19 however remains unclear. We performed a systematic assessment of sequelae across all body systems, focusing on whether COVID-19 is associated with ...
Yong Xiang, Ruoyu Zhang, Jinghong Qiu, Hon-Cheong So   +3 more
doaj   +1 more source

UK Biobank — a new era in genomic medicine [PDF]

Nature Reviews Genetics, 2018
Two studies in Nature describe the full data set of the UK Biobank resource, which contains genome-wide genetic data, clinical measurements and health records for ~500,000 individuals, and reveal insights into the brain’s genetic architecture.
openaire   +2 more sources

CryoArks – The UK's first zoological biobank

, 2022
Abstract of conference oral presentation on CryoArks – The UK's first zoological biobank by Principal Curator Of Vertebrates Andrew Kitchener of Principal Curator Of Vertebrates National Museums of Scotland Edinburgh United Kingdom for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
openaire   +1 more source

Bidirectional Mendelian randomization reveals associations between telomere length and autoimmune diseases

Trials
Background Autoimmune diseases are a group of complex chronic illnesses that affect multiple organs or body systems. These diseases are characterized by tissue damage, impaired organ function, and increased risk of malignancies, and elevated mortality ...
Qin Jiang, Chenxi Yu, Shiben Zhu, Yang Liu, Min Ye   +4 more
doaj   +1 more source

Social determinants of health, accelerated biological aging, and long-term health outcomes

Nature Communications
Social determinants of health (SDHs) are the primary drivers of health inequalities, but whether biological aging plays a role in linking SDHs to health outcomes remains unclear.
Jiang Li, Jie Li, Xiaoqin Xu, Wenqi Shen, Ying Sun, Yanqi Fu, Xiao Tan, Ningjian Wang, Lu Qi, Bin Wang, Yingli Lu   +10 more
doaj   +1 more source