Results 81 to 90 of about 7,704,969 (300)

Baseline characteristics of UK Biobank (all), Welsh UK Biobank participants (with UK Biobank, primary and secondary care data linkage), and CPRD (primary and secondary care data linkage).

, 2016
Baseline characteristics of UK Biobank (all), Welsh UK Biobank participants (with UK Biobank, primary and secondary care data linkage), and CPRD (primary and secondary care data linkage).
Sinead Brophy (40627), Mark Atkinson (165217), Nishi Chaturvedi (130777), Rohini Mathur (3122613), Naomi Allen (140094), Sophie V Eastwood (3122607), Simon de Lusignan (2416), Cathie Sudlow (259959), Robin Flaig (3122610)   +8 more
core   +1 more source

Macular thickness varies with age-related macular degeneration genetic risk variants in the UK Biobank cohort

, 2021
To evaluate the influence AMD risk genomic variants have on macular thickness in the normal population. UK Biobank participants with no significant ocular history were included using the UK Biobank Resource (project 2112).
Hysi, Pirro, UK Biobank Eye and Vision Consortium, Patasova, Karina, Lotery, Andrew, Patel, Praveen J., Kaye, Rebecca   +5 more
core   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Demographics of lipoprotein(a) and stroke: The UK biobank

American Journal of Preventive Cardiology
Lipoprotein(a) [Lp(a)] is associated with ischemic stroke, but the strength of association based on demographic differences remains unclear. We aimed to investigate the association between Lp(a)>125 nmol/L and stroke by age, sex, and racial/ethnic subgroups.Using data from the UK Biobank, we included 353,309 participants with an Lp(a) measurement ...
Andrew S. Kao, Jonathan Kermanshahchi, Shamim Khosrowjerdi, Alexander C. Razavi, Jacqueline Levene, Mikaila Reyes, Parveen Garg, W.T. Longstreth, Kristiina Rannikmae, Cathie Sudlow, Michael Tsai, Sotirios Tsimikas, Anum Saeed, Harpreet S. Bhatia   +13 more
openaire   +4 more sources

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Association of sugar intake from different sources with incident dementia in the prospective cohort of UK Biobank participants

Nutrition Journal, 2023
Background Dementia is a common disease with around 55 million cases worldwide. Therefore, dietary changes and lifestyle interventions are important approaches to delay the progress of a decline in cognitive function.
Sylva M. Schaefer, Anna Kaiser, Gerrit Eichner, Mathias Fasshauer   +3 more
doaj   +1 more source

Phenome-wide Heritability Analysis of the UK Biobank

PLOS Genetics, 2016
Heritability estimation provides important information about the relative contribution of genetic and environmental factors to phenotypic variation, and provides an upper bound for the utility of genetic risk prediction models. Recent technological and statistical advances have enabled the estimation of additive heritability attributable to common ...
Tian Ge, Chia-Yen Chen, Benjamin M. Neale, Mert R. Sabuncu, Jordan W. Smoller   +4 more
openaire   +7 more sources

UK Biobank Asthma Phenotype

, 2019
UK Biobank Asthma ...
Kenan Direk (4588036)
core   +1 more source

Multimodal population brain imaging in the UK Biobank prospective epidemiological study [PDF]

, 2016
Medical imaging has enormous potential for early disease prediction, but is impeded by the difficulty and expense of acquiring data sets before symptom onset.
Andersson, JLR, Hudson, S, Andreas J Bartsch, Andersson, Jesper L., Hudson, Sarah, Jbabdi, Saad, Andersson, Jesper L.R., Junqian Xu, Smith, SM, Douaud, Gwenaëlle, Smith, Stephen M., Gwenaëlle Douaud, Sarah Hudson, Xu, J, Matthews, PM, Bangerter, NK, Andersson, JL, Iulius Dragonu, Alfaro-Almagro, Fidel, David L Thomas, Thomas W Okell, Neal K Bangerter, Steve Garratt, Rory Collins, Jenkinson, Mark, Xu, Junqian, Douaud, Gwanaelle, Yacoub, E, Collins, Rory, Miller, KL, Bartsch, AJ, Okell, TW, Jesper L R Andersson, Griffanti, L, Jbabdi, S, Alfaro-Almagro, F, Collins, R, Miller, Karla, Okell, Thomas W., Thomas, David L., Stephen M Smith, Douaud, Gwena�lle, Griffanti, Ludovica, Saad Jbabdi, Karla L Miller, Stamatios N Sotiropoulos, Sotiropoulos, Stamaios N., Jenkinson, M, Bangerter, Neal K., Garratt, Steve, Mark Jenkinson, Ludovica Griffanti, Peter Weale, Paul M Matthews, Thomas, DL, Douaud, G, Miller, Karla L., Dragonu, Iulius, Smith, Stephen, Dragonu, J, Weale, Peter, Sotiropoulos, SN, Garratt, S, Dragonu, I, Matthews, Paul M., Weale, P, Yacoub, Essa, Sotiropoulos, Stamatios N., Fidel Alfaro-Almagro, Essa Yacoub, Bartsch, Andreas J.   +70 more
core   +1 more source