Results 1 to 10 of about 108,565 (124)

UK Longitudinal Linkage Collaboration (UK LLC): The National Trusted Research Environment for Longitudinal Research [PDF]

International Journal of Population Data Science
Introduction The UK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment (TRE) for the UK's longitudinal research community, supporting the UK's unparalleled collection of Longitudinal Population Studies (LPS ...
Andy Boyd, Katharine Evans, Emma Turner, Robin Flaig, Jacqui Oakley, Kirsteen Campbell, Richard Thomas, Stela McLachlan, Matthew Crane, et al.   +9 more
doaj   +7 more sources

A novel protocol for a "Citizen Panel" for diverse Public and Participant Involvement in the review and development of the process to access data in the UK Longitudinal Linkage Collaboration Trusted Research Environment [PDF]

International Journal of Population Data Science
Background Researchers can apply to UK Longitudinal Linkage Collaboration (UK LLC) to access Longitudinal Population Study (LPS) data linked to health, non-health administrative and geo-environmental data.
Lidis Garbovan, Betty O. Idemudia, Robin Flaig, Kirsteen Campbell, Katharine Evans, Andy Boyd, Sarah Cunningham-Burley, Emma L. Turner   +7 more
doaj   +2 more sources

Experience-based co-design informed development of a toolbox to help optimise primary care support during transition from children’s hospice care: HOPSCOTCH study protocol [PDF]

BMJ Open
Introduction The HOPSCOTCH study ‘Helping Optimise Primary Care Support During Transition From Children’s Hospice Care’ aims to develop a toolbox to enable engagement of primary care services in the care of young people with life-limiting conditions (LLC)
George Peat, Sarah Mitchell, Lorna Katharine Fraser, Emma Chapman, Lucy Ziegler, Ben Morris, Joanna Elverson, Paul Carder, Josefine Magnusson, Jordanne Wozencroft, Tagore Charles, Katie Tallowin   +11 more
doaj   +2 more sources

How public and participant voices have influenced the UK Longitudinal Linkage Collaboration and its Trusted Research Environment.

International Journal of Population Data Science, 2022
Objectives UK longitudinal population studies have complex governance structures and participant safeguards. As a new Trusted Research Environment (TRE) for >20 longitudinal studies, the UK Longitudinal Linkage Collaboration (UK LLC) must ensure ...
Kirsteen Campbell, Rebecca Whitehorn, Andy Boyd, Robin Flaig, Stela McLachlan, Christie Levein, Jacqueline Oakley, Sarah Chave, Michael Gregg, Della Ogunleye   +9 more
doaj   +1 more source

UK Longitudinal Linkage Collaboration – and the challenges in creating a new Longitudinal Populations Studies linked data resource.

International Journal of Population Data Science, 2022
Objectives The UK Longitudinal Linkage Collaboration (UK LLC) is a new, unprecedented infrastructure enabling research into the COVID-19 pandemic.
Robin Flaig, Jacqui Oakley, Kirsteen Campbell, Katharine Evans, Stela McLachlan, Richard Thomas, Emma Turner, Andy Boyd   +7 more
doaj   +1 more source

The UK Longitudinal Linkage Collaboration: a trusted research environment for the longitudinal research community.

International Journal of Population Data Science, 2022
Objectives The COVID-19 Longitudinal Health and Wellbeing National Core Study utilises data from Longitudinal Population Studies (LPS) and whole-population NHS databases: yet no resource existed linking multiple LPS to COVID-19 records.
Andy Boyd, Robin Flaig, Jacqui Oakley, Kirsteen Campbell, Katharine Evans, Stella McLachlan, Richard Thomas, Emma Turner   +7 more
doaj   +1 more source

Cosmic-Ray neutron Sensor PYthon tool (crspy 1.2.1): an open-source tool for the processing of cosmic-ray neutron and soil moisture data [PDF]

Geoscientific Model Development, 2021
Understanding soil moisture dynamics at the sub-kilometre scale is increasingly important, especially with the continuous development of hyper-resolution land surface and hydrological models.
D. Power, M. A. Rico-Ramirez, S. Desilets, D. Desilets, R. Rosolem, R. Rosolem   +5 more
doaj   +1 more source

The challenges of developing an application process for a new linked data resource.

International Journal of Population Data Science, 2022
Objectives Developing a rigorous application process for COVID-19 linked data within the UK Longitudinal Linkage Collaboration’s Trusted Research Environment (TRE) included balancing the requirements of 20+ longitudinal studies and several data providers
Stela McLachlan, Samantha Berman, Katharine Evans, Christie Levein, Rebecca Whitehorn, Jacqueline Oakley, Kirsteen Campbell, Robin Flaig   +7 more
doaj   +1 more source

UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. IV. Comparative Studies of UK-2A with Antimycin A3 on Cytotoxic Activity and Reactive Oxygen Species Generation in LLC-PK1 Cells.

The Journal of Antibiotics, 1999
UK-2A, a novel antifungal antibiotic, is a structural relative of antimycin A3 (AA) and its mode of action is similar to that of AA which inhibits mitochondrial electron transport at complex III. In spite of their structural resemblance, AA had strong cytotoxicity while UK-2A had little cytotoxicity against LLC-PK1 cells as well as other types of ...
H, Takimoto, K, Machida, M, Ueki, T, Tanaka, M, Taniguchi   +4 more
  +9 more sources

CYTOCON: The manually curated database of human in vivo cell and molecule concentrations

CPT: Pharmacometrics & Systems Pharmacology, 2023
Cell and cYTOkine CONcentrations DataBase (CYTOCON DB) is a project undertaken by the InSysBio team and aimed at the development of a database that allows collecting, processing, and visualizing publicly available in vivo human data on baseline ...
Vladislav Leonov, Ekaterina Mogilevskaya, Elita Gerasimuk, Nail Gizzatkulov, Oleg Demin   +4 more
doaj   +1 more source