Results 81 to 90 of about 558,447 (316)

South African Media and Politics: Is the Three Models Approach Still Valid After Two Decades?

open access: yesMedia and Communication
When Hallin and Mancini (2004) produced their watershed three models theory, South Africa was a new democracy barely a decade old. Even then, along with other countries of the Global South, the experience of a young democracy posed certain critical ...
Bernadine Jones, Adrian Hadland
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Playing the game: a study of public relations, politics and the construction of Islam in the UK public sphere. [PDF]

open access: yes, 2015
This doctoral thesis explores the relationship between politics, Islam and the news media in the UK. Using the theory of mediatisation as a framework for understanding media power, it argues that the relationship between politics and the media cannot be ...
Forbes, Claire
core  

The Media and the UK Supreme Court

open access: yesCambridge Journal of International and Comparative Law, 2012
The Supreme Court is understandably pleased with the “close relationship with media organisations”1 that its five-person communications team has built up over the past couple of years. In the Court’s annual report for 2010/11, it describes two television documentaries broadcast on minority channels as the “highlight of this year”.2 These programmes ...
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

British media coverage of the Kosovo conflict [PDF]

open access: yes, 2005
New Labour presented Nato's Kosovo campaign in 1999 as Britain's first war fought for purely humanitarian reasons, and this framing of the Nato campaign seemed to become the dominant image of the conflict in the British media.
Latham, Marc Lynton
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Computerized Interactive Gaming via Supporting Vector Machines

open access: yesInternational Journal of Computer Games Technology, 2008
Computerized interactive gaming requires automatic processing of large volume of random data produced by players on spot, such as shooting, football kicking, and boxing.
Y. Jiang, J. Jiang, I. J. Palmer
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Urinal or conduit? Institutional information flow between the UK intelligence services and the news media [PDF]

open access: yes, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ Sage Publications 2013.Since the 1990s, the Secret Intelligence Service (MI6) and the Security Service (MI5) have developed formal links ...
Paul Lashmar (16224212)   +2 more
core   +1 more source

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