Results 201 to 210 of about 151,242 (304)

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Extracellular Vesicles Derived from Natural Biological Resources and Their Potential to Facilitate Skin Regeneration and Rejuvenation. [PDF]

Pharmaceutics
Yang Z, Li S, Zhang H, Sui Z, Li N.
europepmc   +1 more source

Production and Purification of Mesenchymal Stem Cell‐Derived Extracellular Vesicles Using Preferential Exclusion Chromatography

ELECTROPHORESIS, EarlyView.
A scalable purification strategy using hydroxyl (OH) monolithic chromatography enables efficient isolation and direct concentration of MSC‐EVs from adherent and microcarrier‐based upstreams. This approach supports process scale‐up while ensuring high purity suitable for therapeutic EV manufacturing.
Katja Vrabec, Andrej Raspor, Darja Božič, Nastja Bizjak Ternik, Ana Železnik, Valentina Novak, Ivana Petrović Koshmak, Maja Leskovec, Aleš Štrancar   +8 more
wiley   +1 more source

Surface markers on supermeres outperform extracellular vesicles in colorectal cancer diagnosis. [PDF]

Sci Rep
Kumar S, Sinclair JA, Shi T, Kim G, Zhu R, Gasper G, Wang Y, Higginbotham JN, Zhang Q, Jeppesen DK, Tutanov O, Hamilton M, Franklin JL, Charest A, Coffey RJ, Senapati S, Chang HC.   +16 more
europepmc   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

Impact of mare milk-derived small extracellular vesicles on proliferation, phagocytosis, and migration in RAW264.7 macrophage. [PDF]

Sci Rep
Wang S, Lan Q, Badama S, Nashun B, Wu Y, Bai Y, Xu R, Ta, Bao X, Fang J, He N, Byambaa T, Damba TA, Dalkh T, Si Q.   +14 more
europepmc   +1 more source

Comparison of Different Encapsulation Techniques in Exosomes Obtained from Goat and Bovine Milk. [PDF]

ACS Omega
de Oliveira MCTG, Costa HPS, Teixeira D, Sousa DOB, Gadelha CRF, Guedes MIF, van Tilburg MF.   +6 more
europepmc   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

A novel immune-isolation method for direct quantification of triglycerides associated with lipoprotein(a). [PDF]

J Lipid Res
Lin L, Su F, Yeang C, Tsimikas S.
europepmc   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

Interdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao, Yue Cao, Zhengting Wu, Yingqi Cao, Qi You, Yuanyuan Xia, Xuejun Tan, Dongxiao Li, Tianxin Qiu, Xiuping Cai, Zhaodi Guo, Lei Zheng, Kewei Zhao   +12 more
wiley   +1 more source