Results 211 to 220 of about 151,242 (304)

Current Research on Aloe-Derived Extracellular Vesicles in Injury Repair. [PDF]

Int J Nanomedicine
Mu Y, Zhang H.
europepmc   +1 more source

Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis

Interdisciplinary Medicine, EarlyView.
Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis. Abstract Interstitial fibrosis is the best indicator of irreversible or ongoing renal injury after kidney transplantation and faces considerable diagnostic challenges.
Wenxuan Zhao, Yang Xu, Yuewen Wang, Shihao Jin, Wenhui Wang, Zeming Yu, Yanwen Zhang, Yuxin Zhang, Deling Kong, Bing Wang, Zhenzhou Wu, Jie Zhao, Yuebing Wang   +12 more
wiley   +1 more source

Standardized sample preparation of paediatric bronchoalveolar lavage fluid for mass spectrometry based proteomic analysis. [PDF]

Mol Cell Pediatr
Freitag N, Schramm D, Stefanski A, Schroeter CB, Stühler K, Poschmann G, Driessen MD.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Plasma Extracellular Vesicles as Liquid Biopsies for Glioblastoma: Biomarkers, Subpopulation Enrichment, and Clinical Translation. [PDF]

Int J Mol Sci
Aibaidula A, Gharibi Loron A, Bouchal SM, Bauman MMJ, You HB, Lucien F, Parney IF.   +6 more
europepmc   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Extracellular vesicles as biomarkers for endometrial cancer - A systematic review. [PDF]

Transl Oncol
Baxter E, Nair S, West Z, Salomon C, Obermair A.   +4 more
europepmc   +1 more source

Capture of adeno‐associated viruses from clarified lysate by continuous flow ultracentrifugation: a comparative study of iodixanol and sucrose gradients

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Adeno‐Associated Virus vectors are widely used in gene therapy due to their safety and efficacy. Despite the interest in their therapeutical application, AAV purification remains a significant challenge. Density gradient ultracentrifugation using cesium chloride, sucrose, or iodixanol gradients are common methods for AAV ...
Sabrina Leigheb, Maral Rahimzadeh, Nikolaus Virgolini, Aida Tleuova, Mahbod Mousavian, Astrid Dürauer, Patricia Pereira Aguilar   +6 more
wiley   +1 more source

Evaluating Outer Membrane Vesicle Isolation Techniques for <i>Borrelia burgdorferi</i> and Their Impact on Vesicle Composition, Gene Expression Profile and Uptake. [PDF]

Antibiotics (Basel)
Jathan J, Pandya JM, Jain M, Kaithalapuram T, Cherukuri D, Sapi E.   +5 more
europepmc   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo, Shih‐Hao Huang, Ting‐Hsuan Dai, Shun‐Cheng Wu, Cheng‐Jung Ho, Cheng‐Chang Lu   +5 more
wiley   +1 more source