Results 21 to 30 of about 151,911 (185)

High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein [PDF]

, 1994
Characterization of the assembly of lipoprotein(a) [Lp(a)] is of fundamental importance to understanding the biosynthesis and metabolism of this atherogenic lipoprotein. Since no established cell lines exist that express Lp(a) or apolipoprotein(a) [apo(a)
Azrolan N., Boerwinkle E., Brunner C., Chiesa G., Chung B. Y., Cotten M., Deutscher S. L., Deutscher S. L., Dieplinger H., Edelberg J. M., Green S., Griffiths G., Guevara J., Jr., Huby T., Ichinose A., Kamboh M. I., Koschinsky M. L., Koschinsky M. L., Koschinsky M. L., Kostner G. M., Kraft H- G., Kraft H. G., Krempler F., Krempler F., Lackner C., Linton M. F., Malgaretti N., McGregor G. R., McLean J. W., Menzel H. J., Phillips M. L., Rader D. J., Sambrook J., Sandholzer C., Scanu A. M., Selden R. F., Sommer A., Stanley P., Trieu V. N., Utermann G., Utermann G., Utermann G., Wagner E., White A. L., Zatloukal K., Zechner R„   +45 more
core   +1 more source

Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography

Journal of Extracellular Vesicles, 2021
The molecular characterization of extracellular vesicles (EVs) has revealed a great heterogeneity in their composition at a cellular and tissue level.
Juan A. Martínez‐Greene, Karina Hernández‐Ortega, Ricardo Quiroz‐Baez, Osbaldo Resendis‐Antonio, Israel Pichardo‐Casas, David A. Sinclair, Bogdan Budnik, Alfredo Hidalgo‐Miranda, Eileen Uribe‐Querol, María del Pilar Ramos‐Godínez, Eduardo Martínez‐Martínez   +10 more
doaj   +1 more source

Optimization of Methods for Determination of the Encapsulation Efficiency of Doxorubicin in the Nanoparticles Based on Poly(lactic-co-glycolic acid) (PLGA)

Разработка и регистрация лекарственных средств, 2020
Introduction. Drug encapsulation efficiency (EE) is the important parameter of the nanoparticle-based drug formulations. Generally, the methods for evaluation of the EE are based on separation of the free and NP-bound fractions of the drug; however ...
T. S. Kovshova, N. S. Osipova, A. S. Fortuna, Yu. V. Ermolenko, O. O. Maksimenko, V. Yu. Balabanyan, S. E. Gelperina   +6 more
doaj   +1 more source

1Progress, applications, challenges and prospects of protein purification technology

Frontiers in Bioengineering and Biotechnology, 2022
Protein is one of the most important biological macromolecules in life, which plays a vital role in cell growth, development, movement, heredity, reproduction and other life activities.
Miao Du, Zhuru Hou, Ling Liu, Ling Liu, Yan Xuan, Xiaocong Chen, Lei Fan, Zhuoxi Li, Benjin Xu, Benjin Xu   +9 more
doaj   +1 more source

Cholesterol nucleation time in gallbladder bile of patients with solitary or multiple cholesterol gallstones [PDF]

, 1992
Patients with multiple cholesterol gallbladder stones have been found to be at a higher risk for the recurrence of gallstones after successful nonsurgical treatment than those with a solitary stone.
Abell, Admirand, Carey, Carey, Christoph von Ritter, Dieter Jüngst, Ekkehard Pratschke, Fiske, Gollish, Groen, Gustav Paumgartner, Holan, Lanzini, O'Donnel, Pattinson, Pomeranz, Sackmann, Schriever, Sedaghat, Shiffman, Smallwood, Spengler, Talalay, Tera, Thomas Lang, Van Erpecum, Villanova, Whiting   +27 more
core   +1 more source

The effect of cerebrospinal fluid-derived exosomes on neural differentiation of adipose mesenchymal stem cells in alginate hydrogel scaffold

یافته‌های نوین در علوم زیستی, 2022
Nowadays, researchers have made extensive efforts to find new treatments for nerve damage. Meanwhile, the role of exosomes in cell-cell communication is considered to be a new mechanism. Exosomes can act as suitable differentiating agents.
Mojtaba Cheravi, Javad Baharara, Parichehreh Yaghmaei, Nasim Hayati Roudbari   +3 more
doaj  

Biophysical evidence for intrinsic disorder in the C-terminal tails of the epidermal growth factor receptor (EGFR) and HER3 receptor tyrosine kinases [PDF]

, 2016
The epidermal growth factor receptor (EGFR)/ErbB family of receptor tyrosine kinases includes oncogenes important in the progression of breast and other cancers, and they are targets for many drug development strategies.
Bose, Ron, Keppel, Theodore R, Monsey, John, Murray, Elisa M, Sarpong, Kwabena, Zhu, Jian   +5 more
core   +2 more sources

Production- and Purification-Relevant Properties of Human and Murine Cytomegalovirus

Viruses, 2021
There is a large unmet need for a prophylactic vaccine against human cytomegalovirus (HCMV) to combat the ubiquitous infection that is ongoing with this pathogen.
Sanda Ravlić, Marija Brgles, Lea Hiršl, Stipan Jonjić, Beata Halassy   +4 more
doaj   +1 more source

A simple method to assess the oxidative susceptibility of low density lipoproteins [PDF]

, 2001
BACKGROUND: Oxidative modification of low density lipoproteins (LDL) is recognized as one of the major processes involved in atherogenesis. The in vitro standardized measurement of LDL oxidative susceptibility could thus be of clinical significance.
A Lavy, B Guerci, B Wallin, C Coudray, CJ Schwartz, D Steinberg, D Steinbergt, H Esterbauer, H Esterbauer, H Ohkawa, JA Buege, JM Brun, M El-Saadani, M Taus, MA Moss, MAQ Arshad, MM Bradford, N Rifai, PN Demacker, TJ Lyons   +19 more
core   +4 more sources

Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

Journal of Extracellular Vesicles, 2018
As a complex biological fluid, human synovial fluid (SF) presents challenges for extracellular vesicle (EV) enrichment using standard methods. In this study of human SF, a size exclusion chromatography (SEC)-based method of EV enrichment is shown to ...
Andrew D. Foers, Simon Chatfield, Laura F. Dagley, Benjamin J. Scicluna, Andrew I. Webb, Lesley Cheng, Andrew F. Hill, Ian P. Wicks, Ken C. Pang   +8 more
doaj   +1 more source