Results 91 to 100 of about 298 (115)
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Baicalin and berberine ultradeformable vesicles as potential adjuvant in vitiligo therapy
Colloids and Surfaces B: Biointerfaces, 20190.5-1% of the world's population is affected by vitiligo, a disease characterized by a gradual depigmentation of the skin. Baicalin and berberine are natural compounds with beneficial activities, such as antioxidant, anti-inflammatory and proliferative effects. These polyphenols could be useful for the treatment of vitiligo symptoms, and their efficacy
Silvia Mir-Palomo +2 more
exaly +3 more sources
Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles
Journal of Controlled Release, 2012The potentiality of ultradeformable vesicles as a possible topical delivery system for asiaticoside, a natural compound obtained from Centella asiatica was evaluated, because this compound exhibits collagen biosynthesis promoting activity. Ultradeformable vesicles were prepared by the extrusion technique; these vesicles were composed of Phospholipon ...
Donatella Paolino +2 more
exaly +4 more sources
In vitro and in vivo topical delivery studies of tretinoin-loaded ultradeformable vesicles
European Journal of Pharmaceutics and Biopharmaceutics, 2014Ultradeformable vesicles are highly promising tools to enhance the percutaneous transport of different drugs such as tretinoin across the skin barrier and also to increase the formulation stability at absorption site and reduce the drug induced irritation.Topical delivery of tretinoin-loaded ultradeformable vesicles (tretinoin-UDV) was evaluated ...
Andreia Ascenso +2 more
exaly +3 more sources
Enhancing Gene Therapy through Ultradeformable Vesicles for Efficient siRNA Delivery
Pharmaceutical NanotechnologyGene therapy is a revolutionary approach aimed at treating various diseases by manipulating the expression of specific genes. The composition and formulation of ultra-deformable vesicles play a crucial role in determining their properties and performance as siRNA delivery vectors.
Chintan Aundhia +2 more
exaly +3 more sources
International Journal of Pharmaceutics, 2010
Transfersomes are highly efficient edge activator (EA)-based ultraflexible vesicles capable of, non-invasively, trespassing skin by virtue of their high, self-optimizing deformability. This investigation presents different approaches for the optimization of Transfersomes for enhanced transepidermal delivery of Diclofenac sodium (DS).
Ghada M El Zaafarany +2 more
exaly +3 more sources
Transfersomes are highly efficient edge activator (EA)-based ultraflexible vesicles capable of, non-invasively, trespassing skin by virtue of their high, self-optimizing deformability. This investigation presents different approaches for the optimization of Transfersomes for enhanced transepidermal delivery of Diclofenac sodium (DS).
Ghada M El Zaafarany +2 more
exaly +3 more sources
Journal of Drug Delivery Science and Technology, 2023
Chintankumar V Patel +2 more
exaly +2 more sources
Chintankumar V Patel +2 more
exaly +2 more sources
Therapeutic Delivery, 2023
Aim: Present research work aimed to explore intravaginal route for the drug delivery for treatment of endometrial cancer (EC). Material & methods: Carboplatin (CBP)-loaded ultradeformable vesicle (CBP-UDV) was prepared and characterized for in vitro quality attributes and evaluated for its efficacy in rabbits using ultrasound imaging after intravaginal
Chintankumar Patel +2 more
openaire +2 more sources
Aim: Present research work aimed to explore intravaginal route for the drug delivery for treatment of endometrial cancer (EC). Material & methods: Carboplatin (CBP)-loaded ultradeformable vesicle (CBP-UDV) was prepared and characterized for in vitro quality attributes and evaluated for its efficacy in rabbits using ultrasound imaging after intravaginal
Chintankumar Patel +2 more
openaire +2 more sources
Planta Medica, 2016
Elastic and ultradeformable liposomes were synthesized and physicochemically characterized to make suitable topical formulations for delivering the anti-inflammatory and anticancer compound 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans-propenoic acid. The average sizes of elastic and ultradeformable liposomes are below 300 nm, while the size distribution ...
Di Francesco, M +8 more
openaire +3 more sources
Elastic and ultradeformable liposomes were synthesized and physicochemically characterized to make suitable topical formulations for delivering the anti-inflammatory and anticancer compound 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans-propenoic acid. The average sizes of elastic and ultradeformable liposomes are below 300 nm, while the size distribution ...
Di Francesco, M +8 more
openaire +3 more sources
Current Drug Targets, 2014
Administration of drugs through skin via transdermal route is a non-invasive approach and applicable for systemic delivery but it is not suitable for drugs having higher molecular weight. Various approaches have been used to improve the efficacy of transdermal route such as vesicular system, iontophoresis, microneedles, use of permeation enhancers, etc.
Karunanidhi, Priyanka, Sanjay, Singh
openaire +2 more sources
Administration of drugs through skin via transdermal route is a non-invasive approach and applicable for systemic delivery but it is not suitable for drugs having higher molecular weight. Various approaches have been used to improve the efficacy of transdermal route such as vesicular system, iontophoresis, microneedles, use of permeation enhancers, etc.
Karunanidhi, Priyanka, Sanjay, Singh
openaire +2 more sources
Current Drug Therapy, 2023
Background: After almost 30 years of study, it is a scientific fact that inflammation is the root cause of arthritis. Objective: Guggul has a beneficial role in arthritis because of its ability to neutralize the NF-kappa factor. A topical drug delivery system is beneficial to overcome the problems associated with oral drug delivery and offers ...
Vineet Mittal +5 more
openaire +1 more source
Background: After almost 30 years of study, it is a scientific fact that inflammation is the root cause of arthritis. Objective: Guggul has a beneficial role in arthritis because of its ability to neutralize the NF-kappa factor. A topical drug delivery system is beneficial to overcome the problems associated with oral drug delivery and offers ...
Vineet Mittal +5 more
openaire +1 more source