Results 101 to 110 of about 298 (115)
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Journal of Microencapsulation, 2008
Superoxide dismutase (SOD) and catalase (CAT) are active scavengers of reactive oxygen species and were incorporated into ultradeformable vesicles with the aim of increasing enzyme bioavailability (skin delivery). These special very adaptable vesicles have been formulated and optimized for enzyme transport in order to penetrate into or across the ...
Simoes, Sandra +3 more
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Superoxide dismutase (SOD) and catalase (CAT) are active scavengers of reactive oxygen species and were incorporated into ultradeformable vesicles with the aim of increasing enzyme bioavailability (skin delivery). These special very adaptable vesicles have been formulated and optimized for enzyme transport in order to penetrate into or across the ...
Simoes, Sandra +3 more
openaire +3 more sources
Langmuir, 2003
We studied lipid aggregate penetration through nanoporous, semipermeable barriers by direct transport measurements in vitro and with the confocal laser scanning microscopy of the skin in vivo. We found that it is necessary to use mixed lipid bilayers with a low resistance to permeabilization and high flexibility to overcome narrow, normally confining ...
Gregor Cevc +3 more
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We studied lipid aggregate penetration through nanoporous, semipermeable barriers by direct transport measurements in vitro and with the confocal laser scanning microscopy of the skin in vivo. We found that it is necessary to use mixed lipid bilayers with a low resistance to permeabilization and high flexibility to overcome narrow, normally confining ...
Gregor Cevc +3 more
openaire +1 more source
Ultradeformable Vesicles as Skin Drug Delivery Systems: Mechanisms of Action
2016Ultradeformable vesicles are liposomes made of phosphatidylcholine with a surfactant being included to impart the deformability. They were shown to enhance the transdermal delivery of drugs. The proposed mechanisms of their action include the possibility for vesicle adsorption, adhesion and may be fusion to the skin surface.
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2009
Abstract Appropriate mixtures of phospholipid and surfactant were found to produce ultradeformable vesicles which were claimed to pass through nanometer pores of the stratum corneum (SC), allowing transdermal drug delivery. However, the precise in vivo fate of encapsulated drug and whether ultradeformable vesicles pass intact through the SC and can ...
Ana Paula Corrêa Oliveira Bahia +4 more
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Abstract Appropriate mixtures of phospholipid and surfactant were found to produce ultradeformable vesicles which were claimed to pass through nanometer pores of the stratum corneum (SC), allowing transdermal drug delivery. However, the precise in vivo fate of encapsulated drug and whether ultradeformable vesicles pass intact through the SC and can ...
Ana Paula Corrêa Oliveira Bahia +4 more
openaire +1 more source
Pharmaceutical Nanotechnology
Objective: The study aimed to address the limitations of oral delivery and enhance the bioavailability of Cilnidipine (often prescribed as antihypertensive drug) (CND) through the development of transdermal patches containing ultra-deformable transferosomes.
Dagada Maheswara Reddy, Mothilal Mohan
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Objective: The study aimed to address the limitations of oral delivery and enhance the bioavailability of Cilnidipine (often prescribed as antihypertensive drug) (CND) through the development of transdermal patches containing ultra-deformable transferosomes.
Dagada Maheswara Reddy, Mothilal Mohan
openaire +2 more sources