Results 91 to 100 of about 193,599 (260)

Logics for Conceptual Data Modelling: A Review [PDF]

Transactions on Graph Data and Knowledge
Information modelling for databases and object-oriented information systems avails of conceptual data modelling languages such as EER and UML Class Diagrams.
Fillottrani, Pablo R., Keet, C. Maria
doaj   +1 more source

UML Deficiencies from the perspective of Automatic Performance Model Generation [PDF]

, 1999
A discussion surrounding the use of UML for distributed system ...
Akehurst, David H., Waters, A. Gill
core  

Highly Sensitive Electrochemical Biosensor Based on Hairy Particles with Controllable High Enzyme Loading and Activity

Advanced Functional Materials, EarlyView.
For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin, Anila Antony, Hongtao Cai, Antonia Debevc, Ceyda Topal, Anne Linhardt, Alla Synytska, Leonid Ionov   +7 more
wiley   +1 more source

A Formal ORM-to -UML Mapping Algorithm [PDF]

The object-role model (ORM) data structure can be represented in the unified modeling language (UML) using the five fact encoding constructs: class attribute, association, association class, sub-class and the association qualifier.
Bollen,Peter
core   +1 more source

One‐Step Coordinated Multi‐Kinetic 4D Printing of Human Vascularized Cardiac Tissues with Selective Fast‐Shrinking Capillaries

Advanced Materials, EarlyView.
This study presents a novel 4D bioprinting technique for fabricating cardiac tissues with complex microvasculature. Unlike traditional 3D printing, it enables capillary‐scale structure formation via selective post‐printing shrinkage. This approach overcomes resolution limits of printing cell‐laden hydrogels, allowing the creation of functional ...
Ester Sapir Baruch, Roni Cohen, Eric Silberman, Michael Namestnikov, Itai Cabilly, Assaf Shapira, Tal Dvir   +6 more
wiley   +1 more source

QuantUM: Quantitative Safety Analysis of UML Models

, 2011
When developing a safety-critical system it is essential to obtain an assessment of different design alternatives. In particular, an early safety assessment of the architectural design of a system is desirable.
A. Aziz, A. Hinton, Adnan Aziz, Christel Baier, D. Latella, David Nicolaas Jansen, E. M. Clarke, Florian Leitner-Fischer, Florian Leitner-Fischer, Gethin Norman, H. Aljazzar, H. Boudali, Husain Aljazzar, Husain Aljazzar, I. Majzik, J.Y. Halpern, Lars Grunske, Lars Grunske, Leslie Lamport, M. Ajmone Marsan, Mieke Massink, S. Bernardi, Stefan Leue, V.G. Kulkarni   +23 more
core   +2 more sources

Advanced Stem Cell Therapy: 3D‐Bioprinted Brain‐Like Transplants for Alzheimer's Disease‐Like Dementia

Advanced Science, EarlyView.
A tri‐component biomimetic bioink(gelatin/alginate/fibrinogen) is developed to protect cells in critical pathological environments in AD. Using this bioink, a 3D‐printed NPC construct optimized for hippocampal transplantation is provided to improve cell retention and differentiation in an AD‐like model. This approach enhances memory recovery and offers
Ke Gai, Yu Song, Dawen Gao, Qingning Nie, Xiao Luo, Caizhe Xu, Changhao Cai, Austin Smith, Xiang Li, Wei Shi, Lei Zhang, Wei Sun, Feng Lin   +12 more
wiley   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Development of an Interaction Model of the Protein–Nanocluster Interface by Machine Learning–Assisted Clustering of Amino Acids

Aggregate, EarlyView.
An interaction model for the interface between ligand‐protected gold nanoclusters and proteins is developed using unsupervised machine learning techniques and validated by molecular dynamics simulations and density functional theory calculations. ABSTRACT The interactions that occur in the interface of proteins and ligand‐stabilised metal nanoclusters ...
Brenda Ferrari, Zohreh Fallah, Maya Khatun, Hannu Häkkinen   +3 more
wiley   +1 more source