Results 51 to 60 of about 85,222 (279)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

ADITU: A mesh-free formulation for the solution of Helmholtz equation in bounded and unbounded domains

open access: yesSoftwareX, 2022
This work describes a mesh-free collocation formulation for the acoustic fluid–fluid coupling among non-homogeneous bounded and unbounded fluid domains.
Gorka Garate   +2 more
doaj   +1 more source

A family of steady two-phase generalized Forchheimer flows and their linear stability analysis

open access: yes, 2013
We model multi-dimensional two-phase flows of incompressible fluids in porous media using generalized Forchheimer equations and the capillary pressure.
Hoang, Luan T.   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Decay of Strong Solutions for 4D Navier-Stokes Equations Posed on Lipschitz Domains

open access: yesAdvances in Mathematical Physics, 2018
Initial-boundary value problems for 4D Navier-Stokes equations posed on bounded and unbounded 4D parallelepipeds were considered. The existence and uniqueness of regular global solutions on bounded parallelepipeds and their exponential decay as well as ...
N. A. Larkin
doaj   +1 more source

Unbounded Hölder Domains

open access: yesThe Journal of Geometric Analysis
Abstract Motivated by the classical bounded Hölder domains, we introduce the notion of an unbounded simply connected Hölder domain. We prove analytic and geometric characterizations of these domains with the aid of the spherical metric and the hyperbolic metric.
openaire   +1 more source

Defining functions for unbounded $C^m$ domains

open access: yesRevista Matemática Iberoamericana, 2013
For a domain \Omega\subset\mathbb{R}^n , we introduce the concept of a uniformly C^m defining function. We characterize uniformly C^m defining functions in terms of the signed ...
Harrington, Phillip, Raich, Andrew
openaire   +4 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Exponential decay for the damped wave equation in unbounded domains

open access: yes, 2015
We study the decay of the semigroup generated by the damped wave equation in an unbounded domain. We first prove under the natural geometric control condition the exponential decay of the semigroup.
Alinhac S.   +12 more
core   +2 more sources

Nonlinear p-Laplacian Problems on Unbounded Domains [PDF]

open access: yesProceedings of the American Mathematical Society, 1992
We consider the p p -Laplacian problem \[ − d i v ( a ( x ) | ∇ u | p − 2 ∇ u ) + b
openaire   +2 more sources

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