Results 71 to 80 of about 4,271,942 (321)
Vibration, 2023 To detect human survivors trapped in buildings after earthquakes by using structure-borne sound it is necessary to have knowledge of vibration transmission in collapsed and fragmented reinforced-concrete buildings.
Marios Filippoupolitis, Carl Hopkins
doaj +1 more source
Fluctuations in Uncertainty [PDF]
SSRN Electronic Journal, 2013 In this essay, the author addresses four questions about uncertainty. First, what are some facts and patterns about economic uncertainty? Both macro and micro uncertainty appear to rise sharply in recessions and fall in booms. Uncertainty also varies heavily across countries - developing countries appear to have about one-third more macro uncertainty ...
openaire +8 more sources
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Ageing transitions in a network of Rulkov neurons
Scientific Reports, 2022 The phenomenon of ageing transitions (AT) in a Erdős–Rényi network of coupled Rulkov neurons is studied with respect to parameters modelling network connectivity, coupling strength and the fractional ratio of inactive neurons in the network.
Dhrubajyoti Biswas, Sayan Gupta
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, 2013 We discuss the problem of runtime verification of an instrumented program that misses to emit and to monitor some events. These gaps can occur when a monitoring overhead control mechanism is introduced to disable the monitor of an application with real ...
Bartocci, Ezio, Grosu, Radu
core +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
F1000ResearchBackground Monte Carlo (MC) is often used when trying to assess the consequences of uncertainty in agent-based models (ABMs). However, this approach is not appropriate when the uncertainty is epistemic rather than aleatory, that is, when it represents a ...
Scott Ferson, Vladimir Stepanov
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Uncertainty and Unemployment [PDF]
Econometrica, 2017 This paper studies the impact of time-varying idiosyncratic risk at the establishmentlevel on unemployment fluctuations over 1972–2009. I build a tractable directed searchmodel with firm dynamics and time-varying idiosyncratic volatility. The model allowsfor endogenous separations, entry and exit, and job-to-job transitions.
openaire +3 more sources
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source