Results 81 to 90 of about 868,219 (267)

From Non-Maleficence to Beneficence: Expanded Ethical Computing in the Era of Large Language Models

open access: yesSocieties
As modern society grows increasingly complex, access to essential services such as healthcare, legal aid, tailored education, and psychological support remains heavily gated by socio-economic, neurological, and systemic barriers.
Evi Togia   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

The Incidence of Sport-Related Anterior Cruciate Ligament Injuries: An Overview of Systematic Reviews Including 51 Meta-Analyses

open access: yesJournal of Functional Morphology and Kinesiology
Background/Objectives: The number of systematic reviews evaluating the incidence of anterior cruciate ligament (ACL) injuries in sports is increasing. To synthesize pooled incidence and prevalence rates of sport-related ACL injuries based on published ...
Javier Martinez-Calderon   +5 more
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Optimal Power Procurement for Green Cellular Wireless Networks Under Uncertainty and Chance Constraints

open access: yesEntropy
Given the increasing global emphasis on sustainable energy usage and the rising energy demands of cellular wireless networks, this work seeks an optimal short-term, continuous-time power-procurement schedule to minimize operating expenditure and the ...
Nadhir Ben Rached   +2 more
doaj   +1 more source

Analyzing Axial Stress and Deformation of Tubular for Steam Injection Process in Deviated Wells Based on the Varied (T,P) Fields

open access: yesThe Scientific World Journal, 2013
The axial stress and deformation of high temperature high pressure deviated gas wells are studied. A new model is multiple nonlinear equation systems by comprehensive consideration of axial load of tubular string, internal and external fluid pressure ...
Yunqiang Liu   +3 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Can Narratives, Conceived as the ‘Currency of Thought’, Open the Black Box?

open access: yesLSE Public Policy Review
Economics has no theory as to how people act when no probabilities are available to judge the successful outcome of their actions, as in radical uncertainty.
David Tuckett
doaj   +1 more source

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