Results 81 to 90 of about 35,778 (326)

Dispersible formulation of artemether/lumefantrine: specifically developed for infants and young children. [PDF]

, 2009
Infants and children under five years of age are the most vulnerable to malaria with over 1,700 deaths per day from malaria in this group. However, until recently, there were no WHO-endorsed paediatric anti-malarial formulations available.
Salim Abdulla, Issaka Sagara, A Teklehaimanot, EA Juma, M Makanga, P Piola, Novartis Drug Regulatory Affairs, S Winnick, S Abdulla   +8 more
core   +2 more sources

Advancing Pharmacometrics in Africa: Insights and Perspectives From the 2025 Pharmacometrics Africa Conference

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacometrics (PMX) in Africa has transitioned from foundational capacity‐building to job creation, scientific leadership, regulatory influence, and health innovation. To accelerate this progress, the 2025 Pharmacometrics Africa Conference (PMXAC‐2025) convened key stakeholders to consolidate the continental PMX community, review progress in local ...
Babatunde Ayodeji Adeagbo, Innocent Gerald Asiimwe, Linda Chaba, Aida N. Kawuma, Francis Williams Ojara, Ochuko Maureen Orherhe, Simon Peter Asiimwe, Veshni Pillay‐Fuentes Lorente, Sharon Sawe, Cassius M. Phogole, Catriona Waitt, Samer Mouksassi, Goonaseelan (Colin) Pillai   +12 more
wiley   +1 more source

Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections [PDF]

, 2013
Background: Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man and whether antimalarial ...
Cox Singh, Janet, Daneshvar, Cyrus, Davis, Timothy M. E., Divis, Paul C. S., Rafa'ee, Mohammad Z., Singh, Balbir, Zakaria, Siti K.   +6 more
core   +1 more source

Filtering Trust: Disclosing the Role of Artificial Intelligence Decreases Trust in Technology, but Does Not Prevent Harm to Body Image After Viewing AI‐Generated Content

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objectives Despite the rapid growth of generative artificial intelligence (AI), virtually no research exists examining the psychological impacts of viewing or interacting with AI‐generated images of people. Additionally, it remains relatively unknown whether informing viewers when images are AI‐generated is an effective way to lessen harm or ...
Brooke L. Bennett, Alexis Lamere, Anastasia Kopan, Ellena Wood, Radha Hari, Evan Wright   +5 more
wiley   +1 more source

Adherence to artemether/lumefantrine treatment in children under real-life situations in rural Tanzania. [PDF]

, 2012
A follow-up study was conducted to determine the magnitude of and factors related to adherence to artemether/lumefantrine (ALu) treatment in rural settings in Tanzania.
Gustafsson, Lars L, Kakoko, Deodatus, Mahindi, Margarita, Petzold, Max, Premji, Zul, Simba, Daudi O, Tomson, Goran   +6 more
core   +2 more sources

Oral quinine for the treatment of uncomplicated malaria

BMJ, 2009
Is ineffective in outpatients and should be used only in rare cases Artemisinin combination therapy is the first line treatment for uncomplicated malaria in nearly all malaria endemic countries in sub-Saharan Africa. This treatment is relatively expensive, but it kills parasites faster than any other method and has few adverse effects.1 The ...
Reyburn, Hugh, Mtove, George, Hendriksen, Ilse, von Seidlein, Lorenz   +3 more
openaire   +1 more source

Human Gene Expression in UncomplicatedPlasmodium falciparumMalaria [PDF]

Journal of Immunology Research, 2015
To examine human gene expression during uncomplicatedP. falciparummalaria, we obtained three samples (acute illness, treatment, and recovery) from 10 subjects and utilized each subject’s recovery sample as their baseline. At the time of acute illness (day 1), subjects had upregulation of innate immune response, cytokine, and inflammation-related genes (
Colborn, J.M., Ylöstalo, J.H., Koita, O.A., Cissé, O.H., Krogstad, D.J.   +4 more
openaire   +4 more sources

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Audit of failure rate of sulfadoxine/pyrimetham combined with chloroquine to treat falciparum malaria at single fourteen-day follow-up

South African Family Practice, 2002
Objective: To assess the failure rate of the present first line treatment regime for uncomplicated falciparum malaria of sulfadoxine/pyrimethamine combined with chloroquine. Design: A before-after study. Setting: Ndumo Clinic, Ingwavuma District, South
C.H. Vaughan Williams, C. La Cock, G.F.J. Henry, A.J. Ross   +3 more
doaj   +1 more source