Results 91 to 100 of about 19,796 (310)

Audit of failure rate of sulfadoxine/pyrimetham combined with chloroquine to treat falciparum malaria at single fourteen-day follow-up

South African Family Practice, 2002
Objective: To assess the failure rate of the present first line treatment regime for uncomplicated falciparum malaria of sulfadoxine/pyrimethamine combined with chloroquine. Design: A before-after study. Setting: Ndumo Clinic, Ingwavuma District, South
C.H. Vaughan Williams, C. La Cock, G.F.J. Henry, A.J. Ross   +3 more
doaj   +1 more source

A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda.

, 2006
Coartem is a fixed-dose combination of artemether-lumefantrine that, given in six doses, provides effective treatment for children with uncomplicated Plasmodium falciparum infection in areas with highly endemic and multidrug-resistant malaria.
Ngamije, D., D'Alessandro, U., Ngamije, D, Fanello, C. I., van Doren, W, van Doren, W., Karema, C., Van Overmeir, C, Fanello, CI, Van Overmeir, C., Van Overmeir, Chantal, D'Alessandro, U, Karema, C   +12 more
core   +1 more source

Effect of acute uncomplicated malaria on platelet counts

Nigerian Postgraduate Medical Journal, 2005
To determine the effect of uncomplicated malaria on platelet count.Adult Nigerians (residing in the Lagos metropolis) who were diagnosed as having uncomplicated malaria were treated with a standard regime of chloroquine. Platelet counts were obtained before treatment, Day 0, and again on day 14 when parasitaemia had been cleared in the patients.
M O, Kehinde, A E, Ohwovoriole, O J, Ekanem, K, Odusote, A T, Abegunde, A, Adeniji, A N, Okechukwu, A E, Esoimeme   +7 more
openaire   +2 more sources

Enantiospecific Acid‐Catalysed Hydroperoxidation of Scalemic Tertiary Benzylic Alcohols Facilitating a Concise Asymmetric Synthesis of Yingzhaosu C

European Journal of Organic Chemistry, EarlyView.
Asymmetric synthesis of antimalarial yingzhaosu C was achieved in 4–5 steps by asymmetric Grignard synthesis of (R)‐gossonorol followed by novel enantiospecific hydroperoxidation. We report a concise asymmetric synthesis of antimalarial yingzhaosu C in 59% ee.
Saranna E. Kavanagh, Claudio Monasterolo, Declan G. Gilheany   +2 more
wiley   +1 more source

Malaria drug shortages in Kenya: a major failure to provide access to effective treatment. [PDF]

, 2009
A key bench mark of successful therapeutic policy implementation, and thus effectiveness, is that the recommended drugs are available at the point of care.
Zurovac, D, Kangwana, Beth B, Snow, RW, Njogu, Julius, Kedenge, Sarah V, Kedenge, SV, Wasunna, B, Njogu, J, Snow, Robert, Kangwana, BB, Zurovac, Dejan, Memusi, Dorothy N, Goodman, Catherine A, Goodman, CA, Snow, Robert W, Wasunna, Beatrice, Memusi, DN   +16 more
core   +1 more source

Management of uncomplicated malaria

Continuing Medical Education, 2008
The key issues in the successful management of malaria are early and accurate diagnosis and urgent treatment with effective drugs. Disease presentation is, however, not specific – progression to complicated disease may be rapid in non-immune persons, particularly in young children and pregnant women, and parasite drug resistance significantly ...
Blumberg, Lucille, Frean, John, Barnes, Karen I.   +2 more
openaire   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Incidence of malaria and efficacy of combination antimalarial therapies over 4 years in an urban cohort of Ugandan children.

PLoS ONE, 2010
BackgroundCombination therapies are now recommended to treat uncomplicated malaria. We used a longitudinal design to assess the incidence of malaria and compare the efficacies of 3 combination regimens in Kampala, Uganda.Methodology/principal ...
Tamara D Clark, Denise Njama-Meya, Bridget Nzarubara, Catherine Maiteki-Sebuguzi, Bryan Greenhouse, Sarah G Staedke, Moses R Kamya, Grant Dorsey, Philip J Rosenthal   +8 more
doaj   +1 more source

Prescriber practices and patient adherence to artemisinin-based combination therapy for the treatment of uncomplicated malaria in Guinea, 2016

Malaria Journal, 2019
Background The World Health Organization recommends the use of artemisinin-based combination therapy (ACT) to treat uncomplicated malaria for the control of malaria across the world.
Alioune Camara, Leah F. Moriarty, Timothée Guilavogui, Papa Sambou Diakité, Joseph Souba Zoumanigui, Sidikiba Sidibé, Ibrahima Bah, Ibrahima Kaba, Djebory Kourouma, Koho Zoumanigui, Mateusz Plucinski   +10 more
doaj   +1 more source

Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin. [PDF]

PLoS ONE, 2013
BackgroundPlasmodium falciparum erythrocyte membrane protein-1 (PfEMP-1) is a highly polymorphic adherence receptor expressed on the surface of infected erythrocytes. Based on sequence homology PfEMP-1 variants have been grouped into three major groups A-
Gwladys I Bertin, Thomas Lavstsen, François Guillonneau, Justin Doritchamou, Christian W Wang, Jakob S Jespersen, Sem Ezimegnon, Nadine Fievet, Maroufou J Alao, Francis Lalya, Achille Massougbodji, Nicaise Tuikue Ndam, Thor G Theander, Philippe Deloron   +13 more
doaj   +1 more source