The mitochondrial protein PGAM5 suppresses energy consumption in brown adipocytes by repressing expression of uncoupling protein 1. [PDF]
Sugawara S +9 more
europepmc +1 more source
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner +10 more
wiley +1 more source
Human adipose tissue expression of uncoupling protein 1 in response to intravenous administration of B-type natriuretic peptide hormone: Results from a randomized controlled crossover study. [PDF]
Bachmann KN +4 more
europepmc +1 more source
Expression of uncoupling proteins-1, -2 and -3 mRNA is induced by an adenocarcinoma-derived lipid-mobilizing factor [PDF]
Bing Chen +7 more
openalex +1 more source
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Effect of the beta-3 adrenergic receptor Trp64Arg and uncoupling protein 1–3826 A > G genotypes on lipid and apolipoprotein levels in overweight/obese and non-obese Chinese subjects [PDF]
Yihong Chen +8 more
openalex +1 more source
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
UNCOUPLING PROTEIN 1 EXPRESSION IN LIPOMA TISSUE AND LIPOMA-DERIVED STEM CELLS [PDF]
Sanja Stojanović +3 more
openalex +1 more source
Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Gabriella Cooper +12 more
wiley +1 more source

