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CDH1 Is a Specific Marker for Undifferentiated Spermatogonia in Mouse Testes1 [PDF]
Masutaka Tokuda +3 more
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Akt mediates self-renewal division of mouse spermatogonial stem cells [PDF]
Inoue, Kimiko +9 more
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Lentiviral vector-mediated transduction of goat undifferentiated spermatogonia
Animal Reproduction Science, 2015Recent studies show that spermatogonial stem cells (SSCs) are able to colonize and form mature spermatozoa following transplantation into germ cell depleted testes of recipient males. Therefore, efficient ways for enrichment and gene transfer into SSCs provides a powerful tool for production of transgenic animals.
Hassan, Abbasi +7 more
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Isolation of Undifferentiated Spermatogonia from Adult and Developing Mouse Testes
2023In the mammalian testis, the mitotic complements of spermatogenic cells are spermatogonia, including spermatogonial stem cells (SSCs) which form the basis of life-long spermatogenesis and male fertility. Thus, investigating spermatogonia and subdivisions thereof is essential to increase our understanding of male germline development and infertility ...
Vera, van Melis +2 more
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Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF
Science, 2000The molecular control of self-renewal and differentiation of stem cells has remained enigmatic. Transgenic loss-of-function and overexpression models now show that the dosage of glial cell line–derived neurotrophic factor (GDNF), produced by Sertoli cells, regulates cell fate decisions of undifferentiated spermatogonial cells that include ...
Meng, X. +13 more
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Analysis of putative biomarkers of undifferentiated spermatogonia in dog testis
Animal Reproduction Science, 2017Spermatogenesis begins after puberty and continues throughout a male's life, and is regulated by spermatogonial stem cells in the seminiferous tubules. Markers of male germ cells, including undifferentiated spermatogonia to fully developed spermatozoa have been identified in rodents, but not in dogs.
Won-Young, Lee +6 more
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Regulation of the Differentiation of the Undifferentiated Spermatogonia
2000In the seminiferous epithelium of adult nonprimate mammals, so-called A-single (As) spermatogonia are the stem cells of spermatogenesis (1–3). Upon division of the As spermatogonia, the daughter cells either migrate away from each other and become two new stem cells, or the cells stay together becoming A-paired (Apr) spermatogonia connected by an ...
de Rooij, D.G. +6 more
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Peritubular macrophages phagocyte remains of undifferentiated spermatogonia in mouse testis
2022AbstractThe cells involved in spermatogenesis are germ-cells, called spermatogonia, classified as: type A-undifferentiated, type A-intermediate and type B. During the spermatogenesis, more than 75% of the germ-cells undergo apoptosis and most of them are phagocyted by Sertoli cells.
María Fernanda Marra +5 more
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A Vasculature-Associated Niche for Undifferentiated Spermatogonia in the Mouse Testis
Science, 2007Mammalian spermatogenesis produces numerous sperm for a long period based on a highly potent stem cell system, which relies on a special microenvironment, or niche, that has not yet been identified. In this study, using time-lapse imaging of green fluorescent protein–labeled undifferentiated spermatogonia (A ...
Shosei, Yoshida +2 more
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The Anatomical Record, 1987
AbstractThe topographical arrangement of the clones of Asingle, Apaired, and Aaligned (As, Apr, and Aal) spermatogonia on the basement membrane of seminiferous tubules of the Chinese hamster was studied. It was found that at least some of these clones are not distributed at random as clones of similar cell number were often seen in clusters. Areas were
de rooij, D. G., Janssen, J. M.
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AbstractThe topographical arrangement of the clones of Asingle, Apaired, and Aaligned (As, Apr, and Aal) spermatogonia on the basement membrane of seminiferous tubules of the Chinese hamster was studied. It was found that at least some of these clones are not distributed at random as clones of similar cell number were often seen in clusters. Areas were
de rooij, D. G., Janssen, J. M.
openaire +2 more sources

