Results 141 to 150 of about 3,589 (156)

A novel undifferentiated spermatogonia-specific surface protein 1 (USSP1) in neonatal mice

Science Bulletin, 2019
Mammalian spermatogenesis is maintained by a rare population of spermatogonial stem cells (SSCs), which are important for male fertility. SSCs remain a subset of undifferentiated spermatogonia, which can be isolated by a combination of surface markers. Specific markers to identify and isolate undifferentiated spermatogonia are lacking.
Zhuoheng, Lin, Puping, Liang, Zhaokai, Yao, Yuxi, Chen, Xiya, Zhang, Rui, Huang, Zhen, Zhang, Minyan, Li, Wenbin, Ma, Haiyan, Zheng, Shanbo, Cao, Guang, Shi, Xiaoyang, Zhao, Zhou, Songyang, Junjiu, Huang   +14 more
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ARHGEF15 is expressed in undifferentiated spermatogonia but is not required for spermatogenesis in mice

Reproductive Biology, 2023
Spermatogenesis is a continual process that relies on the activities of undifferentiated spermatogonia, which contain spermatogonial stem cells (SSCs) that serve as the basis of spermatogenesis. The gene expression pattern and molecular control of fate decisions of undifferentiated spermatogonia are not well understood.
Yu-Jun, Wang, Shuang, Li, Hai-Ping, Tao, Xiao-Na, Zhang, You-Gui, Fang, Qi-En, Yang   +5 more
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THY1 as a reliable marker for enrichment of undifferentiated spermatogonia in the goat

Theriogenology, 2013
Spermatogonial stem cells are unique cells of testes that can restore fertility upon transplantation into recipient testes. However, use of suitable markers for enrichment of these cells have important potential application. THY1, is an established conserved marker of spermatogonial stem cells in bovine, rodents, and primates, but there is no ...
Hassan, Abbasi, Mojtaba, Tahmoorespur, Sayyed Morteza, Hosseini, Zahra, Nasiri, Mehrnoosh, Bahadorani, Mahdi, Hajian, Mohammad Reza, Nasiri, Mohammad Hossein, Nasr-Esfahani   +7 more
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Morphology, proliferation, and differentiation of undifferentiated spermatogonia in the chinese hamster and the ram

The Anatomical Record, 1982
AbstractThe population of undifferentiated spermatogonia was studied in whole mounted seminiferous tubules of the Chinese hamster and the ram. The morphology of the differentiating spermatogonia in the ram is also described.The nuclear morphology of the undifferentiated spermatogonia was found to vary considerably.
Lok, D., Weenk, D., de rooij, D. G.
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GFRα‐1 is a reliable marker of bovine gonocytes/undifferentiated spermatogonia: A mini‐review

Anatomia, Histologia, Embryologia, 2020
AbstractIdentification of the specific biomarkers is of great importance to enrich and expand the gonocytes or spermatogonial stem cells (SSCs) in livestock. The glial cell line‐derived neurotrophic factor (GDNF) family receptor alpha‐1 (GFRα‐1) is a conserved marker of the gonocytes/SSCs in multiple species including rodents, primates and human ...
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Identifying undifferentiated spermatogonia in patients with Klinefelter syndrome

Nature Reviews Urology, 2022
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CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes.

Biology of reproduction, 2007
In the mammalian testis, spermatogenesis is initiated from a subset of stem cells belonging to undifferentiated type A spermatogonia. In spite of the biologic significance of undifferentiated type A spermatogonia, little is known about their behavior and properties because of a lack of specific cell surface markers.
Masutaka, Tokuda, Yuzo, Kadokawa, Hiroki, Kurahashi, Tohru, Marunouchi   +3 more
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PLZF protein forms a complex with protein TET1 to target TCF7L2 in undifferentiated spermatogonia

Theriogenology
The transcription factor promyelocytic leukemia zinc finger (PLZF, also known as ZBTB16) is critical for the self-renewal of spermatogonial stem cells (SSCs). However, the function of PLZF in SSCs is not clear. Here, we found that PLZF acted as an epigenetic regulator of stem cell maintenance and self-renewal of germ cells.
Xiaomin Du, Donghui Yang, Xiuwei Yu, Yudong Wei, Wenbo Chen, Yuanxin Zhai, Fanglin Ma, Mengfei Zhang, Shicheng Wan, Yunxiang Li, Xinchun Yang, Aili Aierken, Ning Zhang, Wenjing Xu, Yuan Meng, Na Li, Mingzhi Liao, Xiaole Yuan, Haijing Zhu, Lei Qu, Na Zhou, Xue Bai, Sha Peng, Fan Yang, Jinlian Hua   +24 more
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Overexpression of TAF4B Promoted the Proliferation of Undifferentiated Spermatogonia in Cattleyak In Vitro

Reproduction in Domestic Animals
ABSTRACTAs the hybrid between cattle and yak, cattleyak is a typical male sterile mammal, and the underlying mechanism for its spermatogenic arrest is still unclear. In this study, the coding region of cattleyak TAF4B gene was cloned by RT‐PCR and analysed by bioinformatics.
Yuan Tian, Peng Zhang, Kemin Jing, Yuqian Li, Binglin Yue, Zhijuan Wu, Wenjing Dong, Jincheng Zhong, Xin Cai   +8 more
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Spermatogonial multiplication in the Chinese hamster. II. Cell cycle properties of undifferentiated spermatogonia.

Cell and tissue kinetics, 1983
The cell cycle properties of undifferentiated spermatogonia in the Chinese hamster were analysed by the fraction of labelled mitoses technique (FLM) in whole mounted seminiferous tubules. The minimum cell cycle time (Tc) was found to be c. 90 hr for the As and 87 hr for the Apr and Aal spermatogonia, which is appreciably longer than for the ...
Lok, D., Jansen, M. T., de rooij, D. G.
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