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Undifferentiated primate spermatogonia and their endocrine control [PDF]

open access: yesTrends in Endocrinology and Metabolism, 2010
The biology of spermatogonial stem cells is currently an area of intensive research and contemporary studies in primates are emerging. Quantitative regulation of sperm output by the primate testis seems to be exerted primarily on the transition from undifferentiated to differentiating spermatogonia.
Tony M Plant
exaly   +3 more sources
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THY1 as a reliable marker for enrichment of undifferentiated spermatogonia in the goat

Theriogenology, 2013
Spermatogonial stem cells are unique cells of testes that can restore fertility upon transplantation into recipient testes. However, use of suitable markers for enrichment of these cells have important potential application. THY1, is an established conserved marker of spermatogonial stem cells in bovine, rodents, and primates, but there is no ...
Mojtaba Tahmoorespur   +2 more
exaly   +3 more sources

Analysis of putative biomarkers of undifferentiated spermatogonia in dog testis

Animal Reproduction Science, 2017
Spermatogenesis begins after puberty and continues throughout a male's life, and is regulated by spermatogonial stem cells in the seminiferous tubules. Markers of male germ cells, including undifferentiated spermatogonia to fully developed spermatozoa have been identified in rodents, but not in dogs.
Hyun-Jung Park   +2 more
exaly   +3 more sources

Regulation of the density of spermatogonia in the seminiferous epithelium of the Chinese hamster: I. Undifferentiated spermatogonia

The Anatomical Record, 1987
AbstractThe topographical arrangement of the clones of Asingle, Apaired, and Aaligned (As, Apr, and Aal) spermatogonia on the basement membrane of seminiferous tubules of the Chinese hamster was studied. It was found that at least some of these clones are not distributed at random as clones of similar cell number were often seen in clusters. Areas were
de rooij, D. G., Janssen, J. M.
openaire   +2 more sources

Regulation of the Differentiation of the Undifferentiated Spermatogonia

2000
In the seminiferous epithelium of adult nonprimate mammals, so-called A-single (As) spermatogonia are the stem cells of spermatogenesis (1–3). Upon division of the As spermatogonia, the daughter cells either migrate away from each other and become two new stem cells, or the cells stay together becoming A-paired (Apr) spermatogonia connected by an ...
de Rooij, D.G.   +6 more
openaire   +2 more sources

Morphology, proliferation, and differentiation of undifferentiated spermatogonia in the chinese hamster and the ram

The Anatomical Record, 1982
AbstractThe population of undifferentiated spermatogonia was studied in whole mounted seminiferous tubules of the Chinese hamster and the ram. The morphology of the differentiating spermatogonia in the ram is also described.The nuclear morphology of the undifferentiated spermatogonia was found to vary considerably.
Dirk G de Rooij
exaly   +4 more sources

Lentiviral vector-mediated transduction of goat undifferentiated spermatogonia

Animal Reproduction Science, 2015
Recent studies show that spermatogonial stem cells (SSCs) are able to colonize and form mature spermatozoa following transplantation into germ cell depleted testes of recipient males. Therefore, efficient ways for enrichment and gene transfer into SSCs provides a powerful tool for production of transgenic animals.
Hassan, Abbasi   +7 more
openaire   +2 more sources

A Vasculature-Associated Niche for Undifferentiated Spermatogonia in the Mouse Testis

Science, 2007
Mammalian spermatogenesis produces numerous sperm for a long period based on a highly potent stem cell system, which relies on a special microenvironment, or niche, that has not yet been identified. In this study, using time-lapse imaging of green fluorescent protein–labeled undifferentiated spermatogonia (A ...
Shosei, Yoshida   +2 more
openaire   +2 more sources

Dysregulated genes in undifferentiated spermatogonia and Sertoli cells are associated with the spermatogenic arrest in cattleyak

Molecular Reproduction and Development, 2022
AbstractHybrid male sterility (HMS) is a reproductive isolation mechanism limiting the formation of fertile offspring through interspecific fertilization. Cattleyak is the interspecific hybrid presenting significant heterosis in several economic traits, but HMS restricted its wide reproduction in cettleyak breeding.
Peng, Zhang   +9 more
openaire   +2 more sources

Peritubular macrophages phagocyte remains of undifferentiated spermatogonia in mouse testis

2022
Abstract The cells involved in spermatogenesis are germ-cells, called spermatogonia, classified as: type A-undifferentiated, type A-intermediate and type B. During the spermatogenesis, more than 75% of the germ-cells undergo apoptosis and most of them are phagocyted by Sertoli cells.
María Fernanda Marra   +5 more
openaire   +1 more source

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