Results 151 to 160 of about 26,198 (189)

Anticoagulant activities of four unfractionated and fractionated heparins

Thrombosis Research, 1978
Abstract Four commercial heparins, two of bovine lung and two of porcine mucosal origin, have been fractionated by gel filtration (and one of them also by ion-exchange chromatography) to yield different fractions whose mean MWs lie in the MW range 7,000–26,000. Three plasma anticoagulant assays have been used to measure the specific activities of the
D A, Lane, I R, Macgregor, R, Michalski, V V, Kakkar   +3 more
openaire   +2 more sources

Subcutaneous unfractionated heparin for the treatment of venous thromboembolism

Current Opinion in Pulmonary Medicine, 2007
When unfractionated heparin is used to treat acute venous thromboembolism, it is usually given by intravenous infusion with dose adjustment in response to activated partial thromboplastin time measurements. These two requirements are a barrier to treatment of venous thromboembolism with unfractionated heparin, and it is uncertain if they are necessary ...
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Unfractionated heparin, time for a change?

Irish medical journal, 1999
In Ireland physician transfer to utilisation of Low Molecular Weight Heparin for Venous Thromboembolism has been slow, despite evidence of efficacy and concern about the level of anticoagulation achieved with Unfractionated Heparin.To examine the effectiveness of Unfractionated Heparin administration in a teaching hospital in Ireland.
P F, Ridgway, J, Crosbie, K A, Hinedi, W, Ghadban, A, Kelly, R, O'Donnell, J, Hollingsworth   +6 more
openaire   +1 more source

Cardiopulmonary bypass in humans: bypassing unfractionated heparin

The Annals of Thoracic Surgery, 2000
Seven anticoagulants besides unfractionated heparin have been used for human cardiopulmonary bypass (CPB), mainly in patients with heparin-induced thrombocytopenia. The collective experience with these alternative anticoagulants provides a perspective on current efforts aimed at improving CPB anticoagulation.
openaire   +2 more sources

Economics of Unfractionated Heparin: Beyond Acquisition Cost

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2004
Despite numerous clinical trials demonstrating advantages of new anticoagulants, unfractionated heparin (UFH) is still used by a number of clinicians in the United States. The reason for this continued use of UFH is not superior efficacy, improved safety, or convenience, but low acquisition cost.
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Standardisation of Unfractionated and Low-Molecular-Weight Heparin

2011
Unfractionated and low-molecular-weight heparins are complex biologicals. Standardisation and global harmonisation of units and methods of measurement are essential for safety and efficacy of this important class of anticoagulants. This chapter describes the traceability of the international unit and current status of the relationship between the ...
openaire   +2 more sources

Unfractionated Heparin

2012
Nektaria Xirouchaki, Dimitrios Georgopoulos, Keith Boniface, Venkatesh Bellamkonda-Athmaram, Lindsay E. Nicolle, Sean M. Bagshaw, Ambica Parmar, Rinaldo Bellomo, Thomas Langer, Franco Valenza, Pietro Caironi, Adam Romanovsky, Sean M. Bagshaw, Jason M. Phillips, Sean Primley, Fernando J. Kim, William H. Shoff, Catherine T. Shoff, David F. Gaieski, Suzanne M. Shepherd   +19 more
openaire   +1 more source

Issues With Monitoring of Unfractionated Heparin in Cirrhosis

Therapeutic Drug Monitoring, 2015
Potze, Wilma, Lisman, Ton
openaire   +3 more sources

Unfractionated Heparin and Low Molecular Weight Heparins

2022
openaire   +1 more source

Nomograms for the Administration of Unfractionated Heparin

Thrombosis and Haemostasis, 2001
A. G. Prentice, J. A. Copplestone, H. M. Kingman, J. Lovett, H. Grubb   +4 more
openaire   +1 more source