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Encyclopaedic dictionary on archaeology of Tatarstan:conceptual problems

Поволжская археология, 2015
Theoretical and methodological problems of creation the glossary for the preparation of encyclopedic dictionary, which is related to the Republic of Tatarstan archaeology are considered in this article.
Abdullin Khalim M., Izmaylov Iskander L., Sitdikov Ayrat G., Khuzin Fayaz Sh.   +3 more
doaj  

Benchmarking the negatives: Effect of negative data generation on the classification of miRNA-mRNA interactions.

PLoS Computational Biology
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally. In animals, this regulation is achieved via base-pairing with partially complementary sequences on mainly 3' UTR region of messenger RNAs (mRNAs ...
Efrat Cohen-Davidi, Isana Veksler-Lublinsky   +1 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Comparison of Different Methodological Approaches to Simulate Geo-Referenced Populations to Be Used in a Cluster Analysis of Childhood Leukaemia Cases in Germany

Epidemiology, Biostatistics and Public Health
Introduction A key methodological challenge in epidemiological studies using a cluster analysis approach is the choice of an appropriate set of controls.
Rossana Di Staso , Emilio Gianicolo
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Measuring Business Ownership Across Countries and Over Time: Extending the COMPENDIA Data Base [PDF]

Since several years EIM Business and Policy Research maintains a data base on business ownership rates across OECD countries, called COMPENDIA (COMParative ENtrepreneurship Data for International Analysis).
André van Stel, Chantal Hartog, J. Cieslik Cieslik   +2 more
core  

Examining collusion and voting biases between countries during the Eurovision song contest since 1957

, 2017
The Eurovision Song Contest (ESC) is an annual event which attracts millions of viewers. It is an interesting activity to examine since the participants of the competition represent a particular country's musical performance that will be awarded a set of
Hopkins, Alexander D., Mantzaris, Alexander V., Rein, Samuel R.   +2 more
core   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

Methodological approaches to differential detection of EBV1/EBV2 and HHV6A/HHV6B in saliva

Инфекция и иммунитет, 2019
Epstein-Barr virus (EBV) and human herpesviruses 6A and 6B (HHV6A and HHV6B) are ubiquitous, infecting all social groups. In Russia, information on the genetic heterogeneity of EBV, even at the level of the main types (EBV1 and EBV2), as well as HHV6A ...
Mariia Igorevna Popkova, Oleg Vladimirovich Utkin, Daria Alekseevna Bryzgalova, Anna Olegovna Senatskaia, Evgeniya Andreevna Soboleva, Nikolai Aleksandrovich Sakharnov, Elena Nikolaevna Filatova, Ekaterina Aleksandrovna Kulova   +7 more
doaj  

A Formal Treatment of Sequential Ignorability

, 2013
Taking a rigorous formal approach, we consider sequential decision problems involving observable variables, unobservable variables, and action variables. We can typically assume the property of extended stability, which allows identification (by means of
Constantinou, Panayiota, Dawid, A. Philip   +1 more
core   +1 more source