Results 171 to 180 of about 14,273 (226)

Unilamellar liposomes covalently coupled on silica gel for liquid chromatography

open access: yesAnalytical and Bioanalytical Chemistry, 2003
Silica gel was used as a support for the covalent coupling of liposomes, which could overcome drawbacks of soft gel beads in column efficiency and separation speed. The influences of the concentration of added dimethylaminopyridine and reaction time on the chloroformate activation reaction of silica gel were investigated.
Xiqin, Mao   +4 more
openaire   +3 more sources

Studies on the encapsulation of diclofenac in small unilamellar liposomes of soya phosphatidylcholine

open access: yesColloids and Surfaces B: Biointerfaces, 2004
The encapsulation of acid (AD) and sodium diclofenac (SD) in small unilamellar liposomes (SUV) as well as the interactions of the drug with the bilayer was studied. SUV was prepared by sonication from multilamellar liposomes containing soya phosphatidylcholine and diclofenac at various proportions.
Lopes, L. B.   +5 more
openaire   +4 more sources

Diffusion and Catalysis Processes in Unilamellar Liposomes

Journal of Liposome Research, 1992
AbstractThis research concerns the study of enzyme loaded unilamellar vesicles as bioreactors. The plant enzyme Ascorbic Acid Oxidase (AAO) was entrapped in unilamellar liposomes.Kinetic study shows that the enzyme activity is largely criptic and that the enzyme in liposomes is partially protected against proteolysis.
ANNESINI MC   +4 more
openaire   +2 more sources

Unilamellar Liposomes with Enhanced Boron Content

Bioconjugate Chemistry, 2005
A new type of boron-rich, DSPC-free, unilamellar liposomes was formed using the novel dual-chain, ionic, nido-carborane lipid, K[nido-7-(C16H33OCH2)2CHOCH2-7,8-C2B9H11] (DAC-16), and cholesterol for encapsulation of an aqueous buffer core. Since DSPC was not necessary for the formation of stable DAC-16 liposomes, the boron concentration of these ...
Tiejun, Li   +2 more
openaire   +2 more sources

Preparation of drug-loaded small unilamellar liposomes and evaluation of their potential for the treatment of chronic respiratory diseases [PDF]

open access: yesInternational Journal of Pharmaceutics, 2018
The aim of the present investigation was to evaluate the influence of liposome formulation on the ability of vesicles to penetrate a pathological mucus model obtained from COPD affected patients in order to assess the potential of such vesicles for the
Vincenzo de Leo   +2 more
exaly   +2 more sources

Extemporaneous preparation of large unilamellar liposomes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1985
Direct contact between lipids solubilized by octyl glucoside and Amberlite XAD-2 beads yielded large liposomes (240 nm diameter) with no residual detergent molecules, in less than 10 min. This extemporaneous preparation of liposomes was prepared with a detergent/bead ratio no higher than 0.12 (mumol/mg) and a phosphatidylcholine/phosphatidylserine ...
J R, Philippot   +2 more
openaire   +2 more sources

Reduction of doxyl stearates by ascorbate in unilamellar liposomes

Archives of Biochemistry and Biophysics, 1990
The effects of the position in the membrane of the doxyl group on the rate of reduction by external ascorbate were studied in large unilamellar liposomes. The key factor increasing the rate of reduction was the degree of partitioning of the nitroxide into the aqueous phase; the doxyl group's proximity to the surface of the membrane was not a major ...
M, Sentjurc, G, Bacic, H M, Swartz
openaire   +2 more sources

Aggregation of unilamellar lecithin liposomes induced by cyclosporin

Journal of Microencapsulation, 1986
Small unilamellar [14C]lecithin liposomes prepared in the presence of cyclosporin sedimented at 12,000 g. Sepharose 4B gel filtration of the resuspended pellet and supernatant yielded identical peaks consisting of small unilamellar liposomes containing cyclosporin. The column retained 40-50 per cent of 14C-labelled liposomes prepared in the presence of
L, Stuhne-Sekalec   +2 more
openaire   +2 more sources

Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1986
We investigated the intrahepatic distribution of small unilamellar liposomes injected intravenously into rats at a dose of 0.10 mmol of lipid per kg body weight. Sonicated liposomes consisting of cholesterol/sphingomyelin (1:1), (A); cholesterol/egg phosphatidylcholine (1:1), (B); cholesterol/sphingomyelin/phosphatidylserine (5:4:1), (C) or cholesterol/
SPANJER, HH   +4 more
openaire   +3 more sources

Temperature-dependent permeability of large unilamellar liposomes

Chemistry and Physics of Lipids, 1984
The temperature-dependent drug leakage from liposomes composed of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol (4:1, by weight) was studied. Experiments were performed in Hepes buffer and 50% fetal calf serum. Large unilamellar liposomes were formed by the reverse phase evaporation process and extruded through a series of ...
R L, Magin, M R, Niesman
openaire   +2 more sources

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