Results 171 to 180 of about 14,273 (226)
Unilamellar liposomes covalently coupled on silica gel for liquid chromatography
Silica gel was used as a support for the covalent coupling of liposomes, which could overcome drawbacks of soft gel beads in column efficiency and separation speed. The influences of the concentration of added dimethylaminopyridine and reaction time on the chloroformate activation reaction of silica gel were investigated.
Xiqin, Mao +4 more
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The encapsulation of acid (AD) and sodium diclofenac (SD) in small unilamellar liposomes (SUV) as well as the interactions of the drug with the bilayer was studied. SUV was prepared by sonication from multilamellar liposomes containing soya phosphatidylcholine and diclofenac at various proportions.
Lopes, L. B. +5 more
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Diffusion and Catalysis Processes in Unilamellar Liposomes
Journal of Liposome Research, 1992AbstractThis research concerns the study of enzyme loaded unilamellar vesicles as bioreactors. The plant enzyme Ascorbic Acid Oxidase (AAO) was entrapped in unilamellar liposomes.Kinetic study shows that the enzyme activity is largely criptic and that the enzyme in liposomes is partially protected against proteolysis.
ANNESINI MC +4 more
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Unilamellar Liposomes with Enhanced Boron Content
Bioconjugate Chemistry, 2005A new type of boron-rich, DSPC-free, unilamellar liposomes was formed using the novel dual-chain, ionic, nido-carborane lipid, K[nido-7-(C16H33OCH2)2CHOCH2-7,8-C2B9H11] (DAC-16), and cholesterol for encapsulation of an aqueous buffer core. Since DSPC was not necessary for the formation of stable DAC-16 liposomes, the boron concentration of these ...
Tiejun, Li +2 more
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Preparation of drug-loaded small unilamellar liposomes and evaluation of their potential for the treatment of chronic respiratory diseases [PDF]
The aim of the present investigation was to evaluate the influence of liposome formulation on the ability of vesicles to penetrate a pathological mucus model obtained from COPD affected patients in order to assess the potential of such vesicles for the
Vincenzo de Leo +2 more
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Extemporaneous preparation of large unilamellar liposomes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1985Direct contact between lipids solubilized by octyl glucoside and Amberlite XAD-2 beads yielded large liposomes (240 nm diameter) with no residual detergent molecules, in less than 10 min. This extemporaneous preparation of liposomes was prepared with a detergent/bead ratio no higher than 0.12 (mumol/mg) and a phosphatidylcholine/phosphatidylserine ...
J R, Philippot +2 more
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Reduction of doxyl stearates by ascorbate in unilamellar liposomes
Archives of Biochemistry and Biophysics, 1990The effects of the position in the membrane of the doxyl group on the rate of reduction by external ascorbate were studied in large unilamellar liposomes. The key factor increasing the rate of reduction was the degree of partitioning of the nitroxide into the aqueous phase; the doxyl group's proximity to the surface of the membrane was not a major ...
M, Sentjurc, G, Bacic, H M, Swartz
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Aggregation of unilamellar lecithin liposomes induced by cyclosporin
Journal of Microencapsulation, 1986Small unilamellar [14C]lecithin liposomes prepared in the presence of cyclosporin sedimented at 12,000 g. Sepharose 4B gel filtration of the resuspended pellet and supernatant yielded identical peaks consisting of small unilamellar liposomes containing cyclosporin. The column retained 40-50 per cent of 14C-labelled liposomes prepared in the presence of
L, Stuhne-Sekalec +2 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1986
We investigated the intrahepatic distribution of small unilamellar liposomes injected intravenously into rats at a dose of 0.10 mmol of lipid per kg body weight. Sonicated liposomes consisting of cholesterol/sphingomyelin (1:1), (A); cholesterol/egg phosphatidylcholine (1:1), (B); cholesterol/sphingomyelin/phosphatidylserine (5:4:1), (C) or cholesterol/
SPANJER, HH +4 more
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We investigated the intrahepatic distribution of small unilamellar liposomes injected intravenously into rats at a dose of 0.10 mmol of lipid per kg body weight. Sonicated liposomes consisting of cholesterol/sphingomyelin (1:1), (A); cholesterol/egg phosphatidylcholine (1:1), (B); cholesterol/sphingomyelin/phosphatidylserine (5:4:1), (C) or cholesterol/
SPANJER, HH +4 more
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Temperature-dependent permeability of large unilamellar liposomes
Chemistry and Physics of Lipids, 1984The temperature-dependent drug leakage from liposomes composed of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol (4:1, by weight) was studied. Experiments were performed in Hepes buffer and 50% fetal calf serum. Large unilamellar liposomes were formed by the reverse phase evaporation process and extruded through a series of ...
R L, Magin, M R, Niesman
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