Results 171 to 180 of about 12,810 (206)

Diffusion and Catalysis Processes in Unilamellar Liposomes

Journal of Liposome Research, 1992
AbstractThis research concerns the study of enzyme loaded unilamellar vesicles as bioreactors. The plant enzyme Ascorbic Acid Oxidase (AAO) was entrapped in unilamellar liposomes.Kinetic study shows that the enzyme activity is largely criptic and that the enzyme in liposomes is partially protected against proteolysis.
ANNESINI MC, DI GIULIO, Antonio, DI MARZIO L, FINAZZI AGRO' A, MOSSA G.   +4 more
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Unilamellar Liposomes with Enhanced Boron Content

Bioconjugate Chemistry, 2005
A new type of boron-rich, DSPC-free, unilamellar liposomes was formed using the novel dual-chain, ionic, nido-carborane lipid, K[nido-7-(C16H33OCH2)2CHOCH2-7,8-C2B9H11] (DAC-16), and cholesterol for encapsulation of an aqueous buffer core. Since DSPC was not necessary for the formation of stable DAC-16 liposomes, the boron concentration of these ...
Tiejun, Li, Julie, Hamdi, M Frederick, Hawthorne   +2 more
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Extemporaneous preparation of large unilamellar liposomes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1985
Direct contact between lipids solubilized by octyl glucoside and Amberlite XAD-2 beads yielded large liposomes (240 nm diameter) with no residual detergent molecules, in less than 10 min. This extemporaneous preparation of liposomes was prepared with a detergent/bead ratio no higher than 0.12 (mumol/mg) and a phosphatidylcholine/phosphatidylserine ...
J R, Philippot, S, Mutaftschiev, J P, Liautard   +2 more
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Reduction of doxyl stearates by ascorbate in unilamellar liposomes

Archives of Biochemistry and Biophysics, 1990
The effects of the position in the membrane of the doxyl group on the rate of reduction by external ascorbate were studied in large unilamellar liposomes. The key factor increasing the rate of reduction was the degree of partitioning of the nitroxide into the aqueous phase; the doxyl group's proximity to the surface of the membrane was not a major ...
M, Sentjurc, G, Bacic, H M, Swartz
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Aggregation of unilamellar lecithin liposomes induced by cyclosporin

Journal of Microencapsulation, 1986
Small unilamellar [14C]lecithin liposomes prepared in the presence of cyclosporin sedimented at 12,000 g. Sepharose 4B gel filtration of the resuspended pellet and supernatant yielded identical peaks consisting of small unilamellar liposomes containing cyclosporin. The column retained 40-50 per cent of 14C-labelled liposomes prepared in the presence of
L, Stuhne-Sekalec, J, Chudzik, N Z, Stanacev   +2 more
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Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1986
We investigated the intrahepatic distribution of small unilamellar liposomes injected intravenously into rats at a dose of 0.10 mmol of lipid per kg body weight. Sonicated liposomes consisting of cholesterol/sphingomyelin (1:1), (A); cholesterol/egg phosphatidylcholine (1:1), (B); cholesterol/sphingomyelin/phosphatidylserine (5:4:1), (C) or cholesterol/
SPANJER, HH, VANGALEN, M, ROERDINK, FH, REGTS, J, SCHERPHOF, GL   +4 more
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Temperature-dependent permeability of large unilamellar liposomes

Chemistry and Physics of Lipids, 1984
The temperature-dependent drug leakage from liposomes composed of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol (4:1, by weight) was studied. Experiments were performed in Hepes buffer and 50% fetal calf serum. Large unilamellar liposomes were formed by the reverse phase evaporation process and extruded through a series of ...
R L, Magin, M R, Niesman
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Making Unilamellar Liposomes Using Focused Ultrasound

Langmuir, 2011
Several techniques are available for making large unilamellar vesicles (LUV) with an average diameter of approximately 100 nm, widely employed as model biomembranes as well as vehicles for drug delivery. Here we describe the use of adaptive focused ultrasound (AFU) for the preparation of LUV from multilamellar vesicles (MLV) and studied the effects of ...
Tejera-Garcia, Roberto, Ranjan, Sanjeev, Zamotin, Vladimir, Sood, Rohit, Kinnunen, Paavo, K.J.   +5 more
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Predicting hydrophilic drug encapsulation inside unilamellar liposomes

International Journal of Pharmaceutics, 2012
A mathematical model has been developed to predict the encapsulation efficiency of hydrophilic drugs in unilamellar liposomes, and will be useful in formulation development to rapidly achieve optimized formulations. This model can also be used to compare drug encapsulation efficiencies of liposomes prepared via different methods, and will assist in the
Xiaoming, Xu, Mansoor A, Khan, Diane J, Burgess   +2 more
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The effects of charge and size on the interaction of unilamellar liposomes with macrophages

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1984
The effect of the positive surface charge of unilamellar liposomes on the kinetics of their interaction with rat peritoneal macrophages was investigated using three sizes of liposomes: small unilamellar vesicles (approx. 25 nm diameter), prepared by sonication, and large unilamellar vesicles (100 nm and 160 nm diameter), prepared by the Lipoprep ...
R A, Schwendener, P A, Lagocki, Y E, Rahman   +2 more
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